Article
Biology
Jens F. Schweihoff, Matvey Loshakov, Irina Pavlova, Laura Kueck, Laura A. Ewell, Martin K. Schwarz
Summary: DeepLabStream is a versatile closed-loop tool that provides real-time pose estimation and delivers posture-dependent stimulations. It has millisecond-range temporal resolution, can utilize different input and output devices, and can be customized for multiple experimental designs. The capabilities of this tool are highlighted in experiments involving freely moving mice and optogenetically labeling active neuronal ensembles.
COMMUNICATIONS BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Marta de Oliveira Barreiros, Felipe Gomes Barbosa, Diego de Oliveira Dantas, Daniel de Matos Luna dos Santos, Sidarta Ribeiro, Giselle Cutrim de Oliveira Santos, Allan Kardec Barros
Summary: Studies using zebrafish in neuro-behavioural research are increasing, with computational methods being one of the most efficient ways to measure fish behavior. The automated system allows for conditioning and assessment of zebrafish behavior, providing greater stability in experiments and individual fish analysis.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Gavin C. Jones, Christina A. Small, Dallin Z. Otteson, Caylor W. Hafen, Jacob T. Breinholt, Paul D. Flora, Matthew D. Burris, David W. Sant, Tysum R. Ruchti, Jordan T. Yorgason, Scott C. Steffensen, Kyle B. Bills
Summary: This study used a Wistar rat model to evaluate the effectiveness of whole-body vibration (WBV) as a preventative measure for the neuronal and behavioral effects of morphine withdrawal. The results showed that concurrent administration of WBV at 80 Hz with morphine significantly reduced adaptations in neuronal activity and dopamine release, as well as modulated the expression of δ-opioid receptors on cholinergic interneurons in the nucleus accumbens. WBV represents a promising adjunct to current intervention for opioid use disorder (OUD).
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Jian Ding, Zheng Ye, Fei Xu, Xiangmei Hu, Hao Yu, Shen Zhang, Yanni Tu, Qiuyu Zhang, Qingyan Sun, Tianmiao Hua, Zhong-Lin Lu
Summary: This study explores the relative contributions of higher-order and primary visual cortex to visual perception by modulating transcranial direct current stimulation. The findings suggest that suppressing top-down influence of the higher-order visual cortex reduces behavioral and neuronal contrast sensitivity and increases contrast thresholds. Additionally, the study indicates that the top-down influence increases contrast sensitivity by reducing internal additive noise and the impact of external noise.
Article
Engineering, Chemical
Yang Chen, Xing Wang, Chengji Deng, Chao Yu, Jun Ding, Hongxi Zhu
Summary: Si@SiC@Si3N4 composites with core-shell structure were synthesized using a catalytic nitridation method, investigating the effect of catalyst content on synthetic powders and proposing a possible formation mechanism of the core-shell structure.
Article
Chemistry, Multidisciplinary
Abdulaziz Almehmadi
Summary: This paper presents the Micro-behavioral Fingerprint Analysis System (MFAS), which records the micro-behavior of the user's fingertips during fingerprint placement to combat attacks on fingerprint verification systems. The experiment shows that the system achieves 100% accuracy in identifying malicious users and distinguishing voluntary from coerced fingerprint placement.
APPLIED SCIENCES-BASEL
(2022)
Article
Biochemistry & Molecular Biology
Michaela Shishmanova-Doseva, Dimitrinka Atanasova, Yordanka Uzunova, Lyubka Yoanidu, Lyudmil Peychev, Pencho Marinov, Jana Tchekalarova
Summary: In a model of TLE, chronic treatment with Lacosamide (LCM) reduced the number of spontaneous motor seizures, corrected the impact of comorbidities on motor activity, anxiety, and memory, and suppressed oxidative stress by increasing superoxide dismutase activity and glutathione levels while decreasing catalase activity and lipid peroxidation in the hippocampus. Additionally, LCM treatment mitigated neuroinflammation and exerted strong neuroprotection in key regions of the brain, suggesting its antioxidant, anti-inflammatory, and neuroprotective properties contribute to its anticonvulsant and beneficial effects on SE-induced behavioral comorbidities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nanoscience & Nanotechnology
Oleg Lupan, Nicolae Magariu, Rasoul Khaledialidusti, Abhishek Kumar Mishra, Sandra Hansen, Helge Krueger, Vasile Postica, Helge Heinrich, Bruno Viana, Luis Katsuya Ono, Beatriz Roldan Cuenya, Lee Chow, Rainer Adelung, Thierry Pauporte
Summary: A comparative investigation was conducted on the influence of post-electroplating treatments on the gas detecting performances of single ZnO nanorods/nanowires. Different treatments were found to enhance material properties, with higher temperature synthesis resulting in increased gas response to H-2 gas. Thermal annealing and hydrothermal treatment were shown to further increase sensor response, indicating potential for high-performance devices in flexible and wearable electronics.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Hematology
Felecia M. Marottoli, Hui Zhang, Eden Flores-Barrera, Emilce Artur de la Villarmois, Frederick C. Damen, Anabel M. M. Miguelez Fernandez, Hannah V. Blesson, Rohan Chaudhary, Anthony L. Nguyen, Amanda E. Nwokeji, Ruju Talati, Ashwin S. John, Kushi Madadakere, Sarah E. Lutz, Kejia Cai, Kuei Y. Tseng, Leon M. Tai
Summary: The loss of endothelial cell APOE3 expression leads to neurovascular dysfunction and abnormalities in neural function. This finding supports the importance of endothelial cell APOE3 in neurovascular regulation, neural circuit function, and behavior.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
(2023)
Article
Neurosciences
Maximilian E. Kirschhock, Helen M. Ditz, Andreas Nieder
Summary: Through experimental studies on crows, it was found that these animals can distinguish the empty set from other countable numerosities, and neurons in the specific region of the endbrain (NCL) show higher activity for the numerical zero. The study results suggest that corvid birds have cognitive abilities similar to human mathematical concepts.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Cassie J. Rowe, Mikayla Crowley-Perry, Elizabeth McCarthy, Terry L. Davidson, Victoria P. Connaughton
Summary: Neurodegenerative diseases are linked with age and incurable, and high blood sugar may impact memory and cognition. By adapting a cognitive task for zebrafish, researchers found that hyperglycemic fish exhibit cognitive deficits after 4 weeks of treatment and respond well to rewards.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
(2021)
Article
Chemistry, Physical
Canan Armutcu, Tunca Karasu, Sena Piskin, Erdogan Ozguer, Lokman Uzun
Summary: In this study, a Quartz Crystal Microbalance (QCM) sensor was used to monitor TNT in aqueous solution in real-time, and a method to detect TNT from vapor phase was also developed. The sensor achieved selective detection of TNT by attaching TNT peptide aptamer on the gold surface of QCM sensor. The results showed that the sensor had excellent selectivity and sensitivity.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Physical
Jianhua Liu, Peng Xu, Jiaxi Zheng, Xiangyu Liu, Xinyu Wang, Siyuan Wang, Tangzhen Guan, Guangming Xie, Minyi Xu
Summary: This article introduces a bio-inspired whisker sensor that uses triboelectric nanogenerators to perceive underwater environments and assist underwater robots in avoiding obstacles.
Article
Neurosciences
Adrian Portales, Pablo Chamero, Sandra Jurado
Summary: Normal and pathological aging have distinct effects on the neurogenic ability of the vomeronasal sensory epithelium, leading to deficiencies in the recognition of social cues and social behavior. Aging disrupts the processing of social olfactory cues, decreasing social odor exploration, discrimination, and habituation. This study reveals fundamental differences in the cellular processes by which natural and pathological aging disrupt the exploration of social information and social behavior.
MOLECULAR NEUROBIOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Kunshu Wang, Xiaofan Xia, Zehui Zhang, Tiegang Gao
Summary: This paper proposes an image detection system by extracting feature hashing of remote sensing images, which is generated from different perspectives like spatial and frequency domain, local and global. The system utilizes optimized Canny operator and compression sensing for edge features and employs gray-level co-occurrence matrix for global texture features. Pseudo-random numbers are used for enhancing security during cloud transmission. Experimental results on four different remote sensing datasets demonstrate the effectiveness and uniqueness of the proposed system, with an average detection accuracy of 99.96%.
DIGITAL SIGNAL PROCESSING
(2023)
Article
Physics, Applied
Ehsan Kheradpezhouh, Julian M. C. Choy, Ehsan Arabzadeh, Vincent R. Daria
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2019)
Article
Neurosciences
Yadollah Ranjbar-Slamloo, Ehsan Arabzadeh
JOURNAL OF PHYSIOLOGY-LONDON
(2019)
Article
Multidisciplinary Sciences
Matthew F. Tang, Lucy Ford, Ehsan Arabzadeh, James T. Enns, Troy A. W. Visser, Jason B. Mattingley
NATURE COMMUNICATIONS
(2020)
Article
Multidisciplinary Sciences
Saba Gharaei, Suraj Honnuraiah, Ehsan Arabzadeh, Greg J. Stuart
NATURE COMMUNICATIONS
(2020)
Article
Cell Biology
Ehsan Kheradpezhouh, Matthew F. Tang, Jason B. Mattingley, Ehsan Arabzadeh
Article
Cell Biology
Conrad C. Y. Lee, Ehsan Kheradpezhouh, Mathew E. Diamond, Ehsan Arabzadeh
Article
Neurosciences
Mansoureh Sabzalizadeh, Mohammad Reza Afarinesh, Saeed Esmaeili-Mahani, Alireza Farsinejad, Ali Derakhshani, Ehsan Arabzadeh, Vahid Sheibani
Summary: The study investigated the effects of stem cell transplantation in the damaged somatosensory barrel cortex of rats and found that the therapy significantly improved sensory discrimination ability. The expression of neuronal markers was higher in the DPSCs group compared to the control group, while GFAP level was lower in the DPSCs group.
BRAIN RESEARCH BULLETIN
(2021)
Article
Neurosciences
Noorya Yasmin Ahmed, Yadollah Ranjbar-Slamloo, Alice Shaam Al Abed, Lingxiao Gao, Yovina Sontani, Alexandre RCom-H'Cheo-Gauthier, Ehsan Arabzadeh, Nathalie Dehorter
Summary: This study reveals that Er81 is expressed in CINs and its specific ablation leads to prominent changes in their molecular, morphologic, and electrophysiological features, particularly amplifying intrinsic delayed-rectifier and hyperpolarization-activated currents. The expression of Er81 is crucial for normal CIN pause and time-locked responses to sensorimotor inputs in awake mice.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Physiology
Sepideh Ghazvineh, Morteza Salimi, Milad Nazari, Mani Garousi, Farhad Tabasi, Kolsoum Dehdar, Alireza Salimi, Hamidreza Jamaati, Javad Mirnajafi-Zadeh, Ehsan Arabzadeh, Mohammad Reza Raoufy
Summary: The study suggests that reintroducing nasal airflow during mechanical ventilation can significantly improve working memory performance in rats. Air-puffs induced enhanced oscillatory activity in specific brain regions, leading to better cognitive outcomes. This non-invasive brain stimulation approach shows promise in alleviating neurological complications caused by prolonged mechanical ventilation.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2021)
Article
Neurosciences
Cong Wang, Teri M. Furlong, Peter G. Stratton, Conrad C. Y. Lee, Li Xu, Sam Merlin, Chris Nolan, Ehsan Arabzadeh, Roger Marek, Pankaj Sah
Summary: During recognition memory, coupled theta activity between the hippocampus and medial prefrontal cortex plays a key role in novelty discrimination, with monosynaptic connections identified as crucial for guiding behavior based on recognition memory.
JOURNAL OF NEUROSCIENCE
(2021)
Review
Neurosciences
Mehdi Adibi, Ilan Lampl
Summary: In the natural environment, organisms constantly adapt to sensory input through neuronal adaptation, which occurs at different processing stages from periphery to cortex. Sensory adaptation plays a crucial role in reducing noise, improving neural coding efficiency, and conserving energy.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Matthew F. Tang, Ehsan Kheradpezhouh, Conrad C. Y. Lee, J. Edwin Dickinson, Jason B. Mattingley, Ehsan Arabzadeh
Summary: The response of cortical neurons to sensory stimuli is influenced by past events and expectation of future events. In this study, researchers investigated how expectation affects orientation selectivity in the primary visual cortex of male mice. They found that neurons enhanced their response to unexpected stimuli, both in awake and anaesthetized mice. A computational model was used to show that trial-to-trial variability in neuronal responses was best characterized when adaptation and expectation effects were combined.
NATURE COMMUNICATIONS
(2023)
Article
Biochemical Research Methods
Ehsan Kheradpezhouh, Wricha Mishra, Ehsan Arabzadeh
Summary: This protocol allows for simultaneous recording and labeling of single cortical neurons in vivo under local application of a chemical, providing a useful tool to investigate the impact of chemicals on sensory information processing by cortical neurons. Juxtacellular labeling helps identify the cell type and morphology of recorded neurons, demonstrating pharmacological modulations in encoding of sensory stimuli. For full details, refer to Kheradpezhouh et al. (2020).
Review
Neurosciences
Mehdi Adibi
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2019)
Correction
Multidisciplinary Sciences
Ehsan Kheradpezhouh, Mehdi Adibi, Ehsan Arabzadeh
SCIENTIFIC REPORTS
(2019)