Use of clinical staging in amyotrophic lateral sclerosis for phase 3 clinical trials

Lithium in patients with amyotrophic lateral sclerosis (LiCALS): a phase 3 multicentre, randomised, double-blind, placebo-controlled trial

(2013)   LANCET NEUROLOGY

What is the relevance of percutaneous endoscopic gastrostomy on the survival of patients with amyotrophic lateral sclerosis?

(2012) Maria João Pena et al.   Amyotrophic Lateral Sclerosis

A proposed staging system for amyotrophic lateral sclerosis

(2012) J. C. Roche et al.   BRAIN

Protocol for a double-blind randomised placebo-controlled trial of lithium carbonate in patients with amyotrophic Lateral Sclerosis (LiCALS) [Eudract number: 2008-006891-31]

(2011) Ammar Al-Chalabi et al.   BMC Neurology

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Clinical diagnosis and management of amyotrophic lateral sclerosis

(2011) Orla Hardiman et al.   Nature Reviews Neurology

Some difficult decisions in ALS/MND

(2010) David J. Oliver et al.   Amyotrophic Lateral Sclerosis

Progression in ALS is not linear but is curvilinear

(2010) Paul H. Gordon et al.   JOURNAL OF NEUROLOGY

Alteration of nutritional status at diagnosis is a prognostic factor for survival of amyotrophic lateral sclerosis patients

(2010) B. Marin et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The natural history of ALS is changing: Improved survival

(2009) Muddasir Qureshi et al.   Amyotrophic Lateral Sclerosis

Practice Parameter update: The care of the patient with amyotrophic lateral sclerosis: Drug, nutritional, and respiratory therapies (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology

(2009) R. G. Miller et al.   NEUROLOGY

Therapy development for ALS: Lessons learned and path forward

(2008) Veena Lanka et al.   Amyotrophic Lateral Sclerosis