Article
Ecology
Niels Jeroen Dingemanse, Yimen G. Araya-Ajoy, David F. Westneat
Summary: The study reveals that selection gradients based on traits measured only once may be attenuated, and deriving individual-mean trait values with few repeats per individual does not remove bias. The three evaluated solutions all require repeated measures for accurate estimates, with errors-in-variables models showing a preference for more precise estimates.
Article
Computer Science, Interdisciplinary Applications
Jose Matias, Johannes Jaeschke
Summary: This paper introduces a new method that can adapt the model structure online, estimate parameters, and optimize economically in the face of uncertain system changes.
COMPUTERS & CHEMICAL ENGINEERING
(2021)
Article
Engineering, Electrical & Electronic
Cheng Cheng, Songyong Liu, Ying Zhang
Summary: This article focuses on the AE localization problem in complex and unknown domains. By introducing schemes based on TR theorem and signal enhancement, two novel robust imaging methods R-DORT and R-TR-MUSIC are proposed, showing the effectiveness and superiority in locating AE sources under complex and uncertain circumstances.
IEEE SENSORS JOURNAL
(2021)
Article
Green & Sustainable Science & Technology
Albert Chukwunonso Diachi, Ayse Tansu, Oseyenbhin Sunday Osemeahon
Summary: Peer influence and self-disclosure have a positive impact on sustaining consumer engagement in social media fashion brand communities, with self-disclosure mediating the relationship between peer influence and sustaining consumer engagement. Ultimately, consumer engagement fosters loyalty to social media brand communities.
Article
Engineering, Chemical
Anwesh Reddy Gottu Mukkula, Sebastian Engell
Summary: This paper discusses the real-time optimization of chemical plants, focusing on addressing model inaccuracies and speeding up convergence by employing modifier adaptation and proactive perturbation schemes.
Article
Multidisciplinary Sciences
Kosuke Itoh, Naho Konoike, Masafumi Nejime, Haruhiko Iwaoki, Hironaka Igarashi, Satoshi Hirata, Katsuki Nakamura
Summary: An increase in the number of neurons in the brain is associated with enhanced cognitive abilities. This study confirmed that the increase in neural processing time accompanied human brain evolution, and quantified the extent of prolongation using noninvasive measurements of brain responses to sounds. The findings suggest that the longer time window for auditory cortical processing in humans is advantageous for analyzing time-varying acoustic stimuli.
SCIENTIFIC REPORTS
(2022)
Article
Business
Marco Bettiol, Mauro Capestro, Eleonora Di Maria, Roberto Ganau
Summary: Becoming an adopter of Industry 4.0 technology increases labor productivity by over 7% for Italian micro, small, and medium enterprises (MSME) in the manufacturing sector, according to new research based on original survey data. The study finds that newly adopting firms experience a labor productivity premium compared to non-adopting firms, which lasts for up to 2 years after adoption. However, the productivity returns show non-linearities based on the number and variety of technologies adopted. The results highlight the importance of industrial policies promoting the adoption of Industry 4.0 technologies by MSMEs, particularly in countries where MSMEs make up the majority of the national industrial system.
SMALL BUSINESS ECONOMICS
(2023)
Article
Multidisciplinary Sciences
Celina Lowen, Bilal Kchouri, Thorsten Lehnert
Summary: This study analyzed the flight to safety effect during the COVID-19 crisis, finding a stronger influence of the equity market on the oil market compared to the gold market. The causality between the equity and oil market was triggered by political factors and the economic impact of the crisis.
Article
Biochemical Research Methods
Robert M. Trout, Christian Viehland, Jianwei D. LI, William Raynor, Al-Hafeez Dhalla, Lejla Vajzovic, Anthony N. Kuo, Cynthia A. Toth, Joseph A. Izatt
Summary: 4D-microscope-integrated optical coherence tomography (4D-MIOCT) is a emerging multimodal imaging technology that combines real-time volumetric OCT (4D-OCT) with standard stereo color microscopy. 4D-OCT provides visual cues not available in standard microscopy, but it is challenging for surgeons to integrate cues from simultaneous-but-separate imaging in real-time. In this work, the fusion of data from each modality guided by segmented 3D features is demonstrated, presenting a more interpretable visualization that combines and registers important cues from both modalities to the surgeons.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Surgery
Stephen E. Thwaites, Stephen G. Holt, Ming K. Yii
Summary: AVF demonstrates superior patency rates throughout the life of the access compared to AVG, with significantly fewer interventions required per patient-year for AVF.
ANZ JOURNAL OF SURGERY
(2021)
Article
Green & Sustainable Science & Technology
Sulaiman O. Fadlallah, Djamal Eddine Benhadji Serradj, Delight M. Sedzro
Summary: This paper explores the viability of wind energy systems in Sudan from a strategic perspective, identifying optimal wind turbine systems and locations across 21 diverse sites. It reveals the potential for substantial pollution prevention and energy cost reduction by implementing wind farms.
Editorial Material
Oncology
Diandra N. Ayala-Peacock, Junzo P. Chino
Summary: This study evaluates the application of active bone marrow sparing defined by (99)mTc-single-photon emission computed tomography imaging in a recent prospective trial, comparing it with existing literature.
Review
Pharmacology & Pharmacy
Gonzalo de Gonzalo, Andres R. Alcantara, Pablo Dominguez de Maria, Jose Maria Sanchez-Montero
Summary: The use of biocatalysis in the synthesis of active pharmaceutical ingredients (APIs) is a powerful strategy, enabled by advancements in molecular biology techniques. This paper presents examples of various enzymes, including lipases, oxidoreductases, and transaminases, that can be integrated into complex pharmaceutical multi-step syntheses. The examples demonstrate high substrate loadings and excellent selectivity, making them promising for industrial applications.
EXPERT OPINION ON DRUG DISCOVERY
(2022)
Article
Business, Finance
Sarah Perret
Summary: This paper examines the experiences of OECD countries with wealth taxes, investigates the various factors leading to their repeal, and discusses whether the current situation may be different and the implications for tax policy.
Article
Development Studies
Amilcar Moreira, Rod Hick
Summary: This paper provides an overview of the initial crisis responses to the coronavirus pandemic and discusses whether and how the COVID-19 crisis and national responses differ from those seen during the Great Recession. The speed and scale of the crisis are indeed distinctive, but claims of symmetry-a crisis affecting all equally-are misplaced. The stimulus packages and employment supports introduced during the pandemic are novel in scope and scale, with a greater emphasis on housing compared to responses to the Great Recession.
SOCIAL POLICY & ADMINISTRATION
(2021)
Article
Medicine, General & Internal
Angela Dos Santos, Katherine Mohr, Martin Jude, Neil G. Simon, Mark Parsons, Sandra Eades, Luke Burchill, Stephen Davis, Geoffrey Donnan, Leonid Churliov, Candice Delcourt
Summary: This study found differences in stroke recognition, risk factors, treatment rates, and outcomes between indigenous and non-indigenous populations in Australia. Indigenous individuals with stroke were younger and had a higher prevalence of modifiable stroke risk factors. Delayed presentation to hospital was also more common among indigenous populations.
INTERNAL MEDICINE JOURNAL
(2022)
Article
Critical Care Medicine
Morgan E. McKeown, Ayush Prasad, Jessica Kobsa, Ilayda Top, Samuel B. Snider, Chelsea Kidwell, Bruce C. V. Campbell, Stephen M. Davis, Geoffrey A. Donnan, Michael Lev, Kevin N. Sheth, Nils Petersen, W. Taylor Kimberly, Matthew B. Bevers
Summary: The study found that a midline shift (MLS) greater than 3 mm is an important threshold for predicting poor outcomes in patients with acute stroke.
NEUROCRITICAL CARE
(2022)
Article
Clinical Neurology
Amrou Sarraj, Mark Parsons, Andrew Bivard, Ameer E. Hassan, Michael G. Abraham, Teddy Wu, Timothy Kleinig, Longting Lin, Chushuang Chen, Christopher Levi, Qiang Dong, Xin Cheng, Ken S. Butcher, Philip Choi, Nawaf Yassi, Darshan Shah, Gagan Sharma, Deep Pujara, Faris Shaker, Spiros Blackburn, Helen Dewey, Vincent Thijs, Clark W. Sitton, Geoffrey A. Donnan, Peter J. Mitchell, Bernard Yan, James G. Grotta, Gregory W. Albers, Stephen M. Davis, Bruce Campbell
Summary: This study found that in patients with M2 occlusion, endovascular thrombectomy was associated with improved clinical outcomes compared to medical management, especially in patients with a perfusion mismatch profile and higher stroke severity.
ANNALS OF NEUROLOGY
(2022)
Article
Clinical Neurology
Nawaf Yassi, Henry Zhao, Leonid Churilov, Bruce C. Campbell, Teddy Wu, Henry Ma, Andrew Cheung, Timothy Kleinig, Helen Brown, Philip Choi, Jiann-Shing Jeng, Annemarei Ranta, Hao-Kuang Wang, Geoffrey C. Cloud, Rohan Grimley, Darshan Shah, Neil Spratt, Der-Yang Cho, Karim Mahawish, Lauren Sanders, John Worthington, Ben Clissold, Atte Meretoja, Vignan Yogendrakumar, Mai Duy Ton, Duc Phuc Dang, Nguyen Thai My Phuong, Huy-Thang Nguyen, Chung Y. Hsu, Gagan Sharma, Peter J. Mitchell, Bernard Yan, Mark W. Parsons, Christopher Levi, Geoffrey A. Donnan, Stephen M. Davis
Summary: The STOP-MSU trial aims to investigate the effectiveness of tranexamic acid in reducing hematoma growth in patients with intracerebral hemorrhage. The study will be conducted in mobile stroke units and emergency departments, with an expected sample size of 180 patients.
STROKE AND VASCULAR NEUROLOGY
(2022)
Article
Clinical Neurology
Peter J. Mitchell, Bernard Yan, Leonid Churilov, Richard J. Dowling, Steven Bush, Thang Nguyen, Bruce C. Campbell, Geoffrey A. Donnan, Zhongrong Miao, Stephen M. Davis
Summary: This study aims to compare the clinical outcomes of direct thrombectomy and bridging IV thrombolysis with thrombectomy in acute ischemic stroke patients with large vessel occlusion, providing unique information for patients with occlusion of large vessels, including the basilar artery, across different ethnic groups.
Article
Public, Environmental & Occupational Health
Mayowa O. Owolabi, Amanda G. Thrift, Ajay Mahal, Marie Ishida, Sheila Martins, Walter Johnson, Jeyaraj Pandian, Foad Abd-Allah, Joseph Yaria, Hoang T. Phan, Greg Roth, Seana L. Gall, Richard Beare, Thanh G. Phan, Robert Mikulik, Rufus O. Akinyemi, Bo Norrving, Michael Brainin, Valery L. Feigin
Summary: Stroke is a major global threat to life and disability, particularly in low- and middle-income countries that struggle to address its challenges. This article provides an overview of primary stroke prevention, estimating the cost and identifying deficiencies in guidelines and primary prevention approaches. Pragmatic solutions are offered, emphasizing the role of governments and population-wide strategies. Implementation of primary stroke prevention involves various stakeholders across the lifespan.
LANCET PUBLIC HEALTH
(2022)
Article
Clinical Neurology
Vignan Yogendrakumar, Teddy Y. Wu, Leonid Churilov, Turgut Tatlisumak, Daniel Strbian, Jiann-Shing Jeng, Timothy J. Kleinig, Gagan Sharma, Bruce C. Campbell, Henry Zhao, Chung Y. Hsu, Atte Meretoja, Geoffrey A. Donnan, Stephen M. Davis, Nawaf Yassi
Summary: This study evaluated the effect of tranexamic acid (TXA) on the growth of intraventricular hemorrhage (IVH) in acute intracerebral hemorrhage (ICH). The results showed that TXA may attenuate the development of IVH following ICH. However, larger studies are needed to further investigate this finding.
EUROPEAN STROKE JOURNAL
(2022)
Article
Clinical Neurology
Amrou Sarraj, Gregory W. Albers, Jordi Blasco, Juan F. Arenillas, Marc Ribo, Ameer E. Hassan, Natalia Perez de la Ossa, Teddy Yuan-Hao Wu, Pere Cardona Portela, Michael G. Abraham, Michael Chen, Laith Maali, Timothy J. Kleinig, Dennis Cordato, Adam Nathan Wallace, Joanna D. Schaafsma, Navdeep Sangha, Daniel P. Gibson, Spiros L. Blackburn, Mercedes De Lera Alfonso, Deep Pujara, Faris Shaker, Margy E. McCullough-Hicks, Javier Luis Moreno Negrete, Arturo Renu, James Beharry, Cecilia Cappelen-Smith, Luis Rodriguez-Esparragoza, Marta Olive-Gadea, Manuel Requena, Tareq Almaghrabi, Vitor Mendes Pereira, Clark Sitton, Sheryl Martin-Schild, Sarah Song, Henry Ma, Leonid Churilov, Peter J. Mitchell, Mark W. Parsons, Anthony Furlan, James C. Grotta, Geoffrey A. Donnan, Stephen M. Davis, Bruce C. V. Campbell
Summary: In patients with large vessel occlusion (LVO) and mild neurological deficits, stratified by perfusion imaging mismatch, endovascular thrombectomy (EVT) did not show improved clinical outcomes compared to medical management (MM). However, EVT was associated with increased functional independence in patients with target mismatch profile.
ANNALS OF NEUROLOGY
(2022)
Article
Clinical Neurology
Alexander C. Flint, Sheila L. Chan, Nancy J. Edwards, Vivek A. Rao, Jeffrey G. Klingman, Mai N. Nguyen-Huynh, Bernard Yan, Peter J. Mitchell, Stephen M. Davis, Bruce C. Campbell, Diederik W. Dippel, Yvo B. W. E. M. Roos, Wim H. van Zwam, Jeffrey L. Saver, Chelsea S. Kidwell, Michael D. Hill, Mayank Goyal, Andrew M. Demchuk, Serge Bracard, Martin Bendszus, Geoffrey A. Donnan
Summary: THRIVE-EVT can be combined with the original THRIVE-c calculation to improve outcome probability estimation for patients with acute ischemic stroke and model the potential improvement in outcomes with endovascular treatment based on variables available at initial presentation.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Clinical Neurology
Skye Coote, Elizabeth Mackey, Anne W. Alexandrov, Dominique A. Cadilhac, Andrei V. Alexandrov, Damien Easton, Henry Zhao, Francesca Langenberg, Andrew Bivard, Michael Stephenson, Mark W. Parsons, Bruce C. V. Campbell, Geoffrey A. Donnan, Stephen M. Davis, Sandy Middleton
Summary: Mobile stroke units (MSUs) provide faster stroke management through immediate assessment and onboard imaging. However, there is limited evidence about the expanded roles of nurses in these services. This study explored the roles and responsibilities of MSU nurses and described two international MSU services, highlighting the potential of a nurse-led telemedicine model for all MSUs.
JOURNAL OF NEUROSCIENCE NURSING
(2022)
Article
Geriatrics & Gerontology
Johannes Tobias Neumann, Le T. P. Thao, Anne M. Murray, Emily Callander, Prudence R. Carr, Mark R. Nelson, Rory Wolfe, Robyn L. Woods, Christopher M. Reid, Raj C. Shah, Anne B. Newman, Jeff D. Williamson, Andrew M. Tonkin, John J. McNeil
Summary: This study analyzed data from ASPREE and found that age, cognitive function, and gait speed were the strongest predictors of disability-free survival in healthy older people. Other factors, such as body mass index and smoking status, were also associated with a worse prognosis.
Article
Clinical Neurology
Fanny Quandt, Fabian Flottmann, Vince Madai, Anna Alegiani, Clemens Kuepper, Lars Kellert, Adam Hilbert, Dietmar Frey, Thomas Liebig, Jens Fiehler, Mayank Goyal, Jeffrey L. Saver, Christian Gerloff, Gotz Thomalla, Steffen Tiedt
Summary: This study aimed to evaluate the importance of EVT treatment and reperfusion level on functional outcome prediction in patients with LVO stroke. The results showed that the importance of reperfusion level was equivalent to EVT treatment allocation for outcome prediction, and was particularly important in patient groups with low NIHSS scores, low ASPECTS scores, and M2 occlusions.
TRANSLATIONAL STROKE RESEARCH
(2023)
Article
Clinical Neurology
Vignan J. Yogendrakumar, Leonid J. Churilov, Peter Mitchell, Timothy Kleinig, Nawaf Yassi, Vincent Thijs, Teddy Wu, Darshan M. Shah, Peter Bailey, Helen Dewey, Philip M. C. Choi, Alice Ma, Tissa Wijeratne, Carlos V. Garcia-Esperon, Geoffrey J. Cloud, Ronil Chandra, Dennis Cordato, Bernard M. Yan, Gagan W. Sharma, Patricia A. Desmond, Mark M. Parsons, Geoffrey Donnan, Stephen Davis, Bruce C. V. Campbell, EXTEND IA TNK Investigators
Summary: This study compared the safety and efficacy of tenecteplase and alteplase in patients with tandem lesion stroke. The results showed that both drugs had similar effects on intracranial reperfusion and 90-day modified Rankin scale. Further research is needed to determine clinically important differences.
Article
Health Care Sciences & Services
Kathleen L. Bagot, Tara Purvis, Shaun Hancock, Henry Zhao, Skye Coote, Damien Easton, Bruce C. Campbell, Stephen M. Davis, Geoff A. Donnan, Shane Foster, Francesca Langenberg, Karen Smith, Michael Stephenson, Stephen Bernard, Sharon McGowan, Bernard Yan, Peter Mitchell, Sandy Middleton, Dominique A. Cadilhac
Summary: This study aimed to investigate the factors influencing the sustainability of the Mobile Stroke Unit (MSU) model. The findings suggest that cohesive teamwork, effective communication, and identified benefits are crucial for ensuring the sustainability of this innovative model.
INTERNATIONAL JOURNAL OF HEALTH POLICY AND MANAGEMENT
(2023)
Article
Medicine, General & Internal
Peter J. Mitchell, Bernard Yan, Leonid Churilov, Richard J. Dowling, Steven J. Bush, Andrew Bivard, Xiao Chuan Huo, Guoqing Wang, Shi Yong Zhang, Mai Duy Ton, Dennis J. Cordato, Timothy J. Kleinig, Henry Ma, Ronil Chandra, Helen Brown, Bruce C. Campbell, Andrew K. Cheung, Brendan Steinfort, Rebecca Scroop, Kendal Redmond, Ferdinand Miteff, Yan Liu, Dang Phuc Duc, Hal Rice, Mark W. Parsons, Teddy Y. Wu, Huy-Thang Nguyen, Geoffrey A. Donnan, Zhong Rong Miao, Stephen M. Davis
Summary: This study compared the clinical outcomes of acute ischemic stroke patients with large vessel occlusion who received direct endovascular thrombectomy or bridging therapy. The results showed that direct endovascular thrombectomy did not achieve non-inferiority compared to bridging therapy, suggesting that bridging therapy should be recommended as the standard treatment.