RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial

Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals – A randomized double- blind pre-clinical study

(2018) Heba A. Ahmed et al.   BEHAVIOURAL BRAIN RESEARCH

Dose–response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke

(2018) Tauheed Ishrat et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cognitive function in stroke survivors: A 10-year follow-up study

(2016) H. Delavaran et al.   ACTA NEUROLOGICA SCANDINAVICA

Eliminating microglia in Alzheimer’s mice prevents neuronal loss without modulating amyloid-β pathology

(2016) Elizabeth E. Spangenberg et al.   BRAIN

Evidence to Consider Angiotensin II Receptor Blockers for the Treatment of Early Alzheimer’s Disease

(2016) Juan M. Saavedra   CELLULAR AND MOLECULAR NEUROBIOLOGY

Rodent Models of Vascular Cognitive Impairment

(2016) Yi Yang et al.   Translational Stroke Research

Cognitive improvement of compound danshen in an Aβ25-35 peptide-induced rat model of Alzheimer’s disease

(2015) Min Liu et al.   BMC Complementary and Alternative Medicine

Antihypertensive Drugs, Prevention of Cognitive Decline and Dementia: A Systematic Review of Observational Studies, Randomized Controlled Trials and Meta-Analyses, with Discussion of Potential Mechanisms

(2015) Laure Rouch et al.   CNS DRUGS

Trajectory of Cognitive Decline After Incident Stroke

(2015) Deborah A. Levine et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Vascular Change and Opposing Effects of the Angiotensin Type 2 Receptor in a Mouse Model of Vascular Cognitive Impairment

(2015) Martina Füchtemeier et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reconstituted mother tinctures of Gelsemium sempervirens L. improve memory and cognitive impairment in mice scopolamine-induced dementia model

(2015) Partha Palit et al.   JOURNAL OF ETHNOPHARMACOLOGY

Compound 21 is pro-angiogenic in the brain and results in sustained recovery after ischemic stroke

(2015) Ahmed Alhusban et al.   JOURNAL OF HYPERTENSION

B-Lymphocyte-Mediated Delayed Cognitive Impairment following Stroke

(2015) K. P. Doyle et al.   JOURNAL OF NEUROSCIENCE

Modulation of Renin-Angiotensin System May Slow Conversion from Mild Cognitive Impairment to Alzheimer's Disease

(2015) Whitney Wharton et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Defining the Microglia Response during the Time Course of Chronic Neurodegeneration

(2015) James E. Vincenti et al.   JOURNAL OF VIROLOGY

Effects of Blood Pressure Lowering in Patients with Acute Ischemic Stroke and Carotid Artery Stenosis

(2014) Mirza Jusufovic et al.   International Journal of Stroke

Telmisartan Reduces Progressive Accumulation of Cellular Amyloid Beta and Phosphorylated Tau with Inflammatory Responses in Aged Spontaneously Hypertensive Stroke Resistant Rat

(2014) Tomoko Kurata et al.   Journal of Stroke & Cerebrovascular Diseases

Low-Dose Candesartan Enhances Molecular Mediators of Neuroplasticity and Subsequent Functional Recovery After Ischemic Stroke in Rats

(2014) Tauheed Ishrat et al.   MOLECULAR NEUROBIOLOGY

Microglia change from a reactive to an age-like phenotype with the time in culture

(2014) Cláudia Caldeira et al.   Frontiers in Cellular Neuroscience

Long-term Effect of Telmisartan on Alzheimer’s Amyloid Genesis in SHR-SR After tMCAO

(2014) Tomoko Kurata et al.   Translational Stroke Research

Synergistic Effects of Ischemia and β-Amyloid Burden on Cognitive Decline in Patients With Subcortical Vascular Mild Cognitive Impairment

(2014) Mi Ji Lee et al.   JAMA Psychiatry

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Protective arms of the renin-angiotensin-system in neurological disease

(2013) Colin Sumners et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Vascular Aspects of Cognitive Impairment and Dementia

(2013) Maximilian Wiesmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

Development of the microglial phenotype in culture

(2013) M. Szabo et al.   NEUROSCIENCE

Protective Effect of Carnosine on Subcortical Ischemic Vascular Dementia in Mice

(2012) Jing Ma et al.   CNS Neuroscience & Therapeutics

Relation Between Change in Blood Pressure in Acute Stroke and Risk of Early Adverse Events and Poor Outcome

(2012) Else C. Sandset et al.   STROKE

RIGOR Guidelines: Escalating STAIR and STEPS for Effective Translational Research

(2012) Paul A. Lapchak et al.   Translational Stroke Research

The changing phenotype of microglia from homeostasis to disease

(2012) Xiao-Guang Luo et al.   Translational Neurodegeneration

Direct Stimulation of Angiotensin II Type 2 Receptor Enhances Spatial Memory

(2011) Fei Jing et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Stroke Treatment Academic Industry Roundtable (STAIR) Recommendations for Maximizing the Use of Intravenous Thrombolytics and Expanding Treatment Options With Intra-arterial and Neuroprotective Therapies

(2011) Gregory W. Albers et al.   STROKE

Vascular Contributions to Cognitive Impairment and Dementia

(2011) Philip B. Gorelick et al.   STROKE

Microglial activation and chronic neurodegeneration

(2010) Melinda E. Lull et al.   Neurotherapeutics

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage

(2009) Paolo Gelosa et al.   JOURNAL OF HYPERTENSION

Vascular Protection with Candesartan after Experimental Acute Stroke in Hypertensive Rats: A Dose-Response Study

(2008) W. Kozak et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS