Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis
出版年份 2014 全文链接
标题
Epitope analysis following active immunization with tau proteins reveals immunogens implicated in tau pathogenesis
作者
关键词
Tau, Immunogenicity, Active immunization, Neuroinflammation, Peripheral response
出版物
Journal of Neuroinflammation
Volume 11, Issue 1, Pages -
出版商
Springer Nature
发表日期
2014-09-02
DOI
10.1186/s12974-014-0152-0
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Specific Targeting of Tau Oligomers in Htau Mice Prevents Cognitive Impairment and Tau Toxicity Following Injection with Brain-Derived Tau Oligomeric Seeds
- (2016) Diana L. Castillo-Carranza et al. JOURNAL OF ALZHEIMERS DISEASE
- Neuronal activity regulates extracellular tau in vivo
- (2014) Kaoru Yamada et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Passive Immunization with Tau Oligomer Monoclonal Antibody Reverses Tauopathy Phenotypes without Affecting Hyperphosphorylated Neurofibrillary Tangles
- (2014) D. L. Castillo-Carranza et al. JOURNAL OF NEUROSCIENCE
- Two Novel Tau Antibodies Targeting the 396/404 Region Are Primarily Taken Up by Neurons and Reduce Tau Protein Pathology
- (2013) Jiaping Gu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain
- (2013) Maj-Linda B Selenica et al. Journal of Neuroinflammation
- Aging enhances classical activation but mitigates alternative activation in the central nervous system
- (2013) Daniel C. Lee et al. NEUROBIOLOGY OF AGING
- Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
- (2013) Kiran Yanamandra et al. NEURON
- Intercellular transfer of tau aggregates and spreading of tau pathology: Implications for therapeutic strategies
- (2013) Florence Clavaguera et al. NEUROPHARMACOLOGY
- Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
- (2013) Cristina d’Abramo et al. PLoS One
- Analysis of the Tau-Associated Proteome Reveals That Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation
- (2012) Andrea D. Thompson et al. ACS Chemical Biology
- Assessing Activation States in Microglia
- (2012) Carol A. Colton et al. CNS & Neurological Disorders-Drug Targets
- Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach
- (2012) Nadege Zommer et al. Current Alzheimer Research
- Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
- (2012) Maj-Linda B. Selenica et al. Neurodegenerative Diseases
- Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
- (2012) Alix de Calignon et al. NEURON
- Trans-Synaptic Spread of Tau Pathology In Vivo
- (2012) Li Liu et al. PLoS One
- Progression of Tau Pathology in Cholinergic Basal Forebrain Neurons in Mild Cognitive Impairment and Alzheimer's Disease
- (2011) Laurel Vana et al. AMERICAN JOURNAL OF PATHOLOGY
- Tau as a Therapeutic Target for Alzheimers Disease
- (2011) A. Boutajangout et al. Current Alzheimer Research
- Anti-tau oligomers passive vaccination for the treatment of Alzheimer disease
- (2011) Rakez Kayed Human vaccines & immunotherapeutics
- Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models
- (2011) Xiyun Chai et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
- (2011) Allal Boutajangout et al. JOURNAL OF NEUROCHEMISTRY
- Tau-Targeted Immunization Impedes Progression of Neurofibrillary Histopathology in Aged P301L Tau Transgenic Mice
- (2011) Mian Bi et al. PLoS One
- Mechanistic Studies of Antibody-Mediated Clearance of Tau Aggregates Using an ex vivo Brain Slice Model
- (2011) Pavan K. Krishnamurthy et al. Frontiers in Psychiatry
- Efficacy and safety of immunization with phosphorylated tau against neurofibrillary tangles in mice
- (2010) Moran Boimel et al. EXPERIMENTAL NEUROLOGY
- Microglia in the CNS: Immigrants from another world
- (2010) Marco Prinz et al. GLIA
- Macrophages in Alzheimer’s disease: the blood-borne identity
- (2010) David Gate et al. JOURNAL OF NEURAL TRANSMISSION
- LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
- (2010) Daniel C Lee et al. Journal of Neuroinflammation
- Immunotherapy Targeting Pathological Tau Prevents Cognitive Decline in a New Tangle Mouse Model
- (2010) A. Boutajangout et al. JOURNAL OF NEUROSCIENCE
- Caspase activation precedes and leads to tangles
- (2010) Alix de Calignon et al. NATURE
- Tau protein and tau aggregation inhibitors
- (2010) Bruno Bulic et al. NEUROPHARMACOLOGY
- Tau-Focused Immunotherapy for Alzheimers Disease and Related Tauopathies
- (2009) Einar Sigurdsson Current Alzheimer Research
- DNA prime–protein boost increased the titer, avidity and persistence of anti-Aβ antibodies in wild-type mice
- (2009) H Davtyan et al. GENE THERAPY
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Accumulation of Aspartic Acid421- and Glutamic Acid391-Cleaved Tau in Neurofibrillary Tangles Correlates With Progression in Alzheimer Disease
- (2009) Gustavo Basurto-Islas et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Aging Analysis Reveals Slowed Tau Turnover and Enhanced Stress Response in a Mouse Model of Tauopathy
- (2008) Chad Dickey et al. AMERICAN JOURNAL OF PATHOLOGY
- Knock-out and transgenic mouse models of tauopathies
- (2007) Franziska Denk et al. NEUROBIOLOGY OF AGING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started