Poly(ADP-ribose) polymerase 2 contributes to neuroinflammation and neurological dysfunction in mouse experimental autoimmune encephalomyelitis

PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity

(2011) Leonardo Cavone et al.   Multiple Sclerosis Journal

Increased Foxp3+ Regulatory T Cells in Poly(ADP-Ribose) Polymerase-1 Deficiency

(2010) F. Nasta et al.   JOURNAL OF IMMUNOLOGY

Parp1 activation in mouse embryonic fibroblasts promotes Pol β-dependent cellular hypersensitivity to alkylation damage

(2010) Elena Jelezcova et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor

(2010) Peter T. Sunderland et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

PARP-1 Deficiency Increases the Severity of Disease in a Mouse Model of Multiple Sclerosis

(2009) Vimal Selvaraj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE

(2009) Mauricio F Farez et al.   NATURE IMMUNOLOGY

Bowman–Birk inhibitor suppresses autoimmune inflammation and neuronal loss in a mouse model of multiple sclerosis

(2008) Tarik Touil et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES