Wnt/beta-Catenin Signaling in Glioma

Prognostic Value of Nuclear β-catenin Overexpression at Invasive Front in Colorectal Cancer for Synchronous Liver Metastasis

(2011) Lin Wang et al.   ANNALS OF SURGICAL ONCOLOGY

β-catenin and Gli1 are prognostic markers in glioblastoma

(2011) Marco Rossi et al.   CANCER BIOLOGY & THERAPY

Dishevelled 2 Signaling Promotes Self-Renewal and Tumorigenicity in Human Gliomas

(2011) T. Pulvirenti et al.   CANCER RESEARCH

STAT3 Is Necessary for Proliferation and Survival in Colon Cancer-Initiating Cells

(2011) L. Lin et al.   CANCER RESEARCH

Frizzled 4 Regulates Stemness and Invasiveness of Migrating Glioma Cells Established by Serial Intracranial Transplantation

(2011) X. Jin et al.   CANCER RESEARCH

Notch1 promotes glioma cell migration and invasion by stimulating β-catenin and NF-κB signaling via AKT activation

(2011) Xiaohua Zhang et al.   CANCER SCIENCE

HAT cofactor TRRAP mediates β-Catenin ubiquitination on the chromatin and the regulation of the canonical Wnt pathway

(2011) Martin G. Finkbeiner et al.   CELL CYCLE

Galectin-3 germline variant at position 191 enhances nuclear accumulation and activation of β-catenin in gastric cancer

(2011) Seok-Jun Kim et al.   CLINICAL & EXPERIMENTAL METASTASIS

GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo

(2011) Kasum Azim et al.   GLIA

Notch1 expression is upregulated in glioma and is associated with tumor progression

(2011) Ligang Jiang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Antitumor effect of aspirin in glioblastoma cells by modulation of β-catenin/T-cell factor–mediated transcriptional activity

(2011) Fengming Lan et al.   JOURNAL OF NEUROSURGERY

Notch1 is an independent prognostic factor for patients with glioma

(2011) Jiang Li et al.   JOURNAL OF SURGICAL ONCOLOGY

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

(2011) Weiwei Yang et al.   NATURE

High  -catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression

(2011) J. Zhang et al.   NEURO-ONCOLOGY

The Notch-2 Gene Is Regulated by Wnt Signaling in Cultured Colorectal Cancer Cells

(2011) Jonas Ungerbäck et al.   PLoS One

A Systematic Screen for Micro-RNAs Regulating the Canonical Wnt Pathway

(2011) Roman Anton et al.   PLoS One

Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma

(2011) Junfang Ji et al.   Cell and Bioscience

Downregulation of WIF-1 by hypermethylation in astrocytomas

(2010) Z. Yang et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Glycogen synthase kinase-3β regulates astrocytic differentiation of U87-MG human glioblastoma cells

(2010) Yan Li et al.   ACTA PHARMACOLOGICA SINICA

Nuclear β-catenin and CD44 upregulation characterize invasive cell populations in non-aggressive MCF-7 breast cancer cells

(2010) Masahiro Uchino et al.   BMC CANCER

Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells

(2010) Xiao Yue et al.   BRAIN RESEARCH

Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription

(2010) Lei Han et al.   BRAIN RESEARCH

Wnt-5a signaling is correlated with infiltrative activity in human glioma by inducing cellular migration and MMP-2

(2010) Masayuki Kamino et al.   CANCER SCIENCE

Wnt/beta-Catenin pathway in human glioma: expression pattern and clinical/prognostic correlations

(2010) Ce Liu et al.   CLINICAL AND EXPERIMENTAL MEDICINE

 -catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma

(2010) M. Anand et al.   HAEMATOLOGICA

α-Catenin inhibits glioma cell migration, invasion, and proliferation by suppression of β-catenin transactivation

(2010) Haitao Ji et al.   JOURNAL OF NEURO-ONCOLOGY

Epidermal growth factor receptor regulates β-catenin location, stability, and transcriptional activity in oral cancer

(2010) Chien-Hsing Lee et al.   Molecular Cancer

Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

(2010) Curtis A Thorne et al.   Nature Chemical Biology

Activated STAT3 Regulates Hypoxia-Induced Angiogenesis and Cell Migration in Human Glioblastoma

(2010) Shin-Hyuk Kang et al.   NEUROSURGERY

The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma

(2010) P N Kongkham et al.   ONCOGENE

Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

(2010) S. A. Ettenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma

(2009) H-C Chen et al.   BRITISH JOURNAL OF CANCER

Notch and Wingless Signaling Cooperate in Regulation of Dendritic Cell Differentiation

(2009) Jie Zhou et al.   IMMUNITY

Inhibitory effects of adenovirus mediated COX-2, Akt1 and PIK3R1 shRNA on the growth of malignant tumor cells in vitro and in vivo

(2009) Zhang   INTERNATIONAL JOURNAL OF ONCOLOGY

Discovery and Characterization of a Small Molecule Inhibitor of the PDZ Domain of Dishevelled

(2009) David Grandy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Survival analysis of 205 patients with glioblastoma multiforme: Clinical characteristics, treatment and prognosis in China

(2009) Xiangyu Ma et al.   JOURNAL OF CLINICAL NEUROSCIENCE

The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo

(2009) Peng Xu et al.   JOURNAL OF NEURO-ONCOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/ -Catenin Signaling Pathway

(2009) O. Saydam et al.   MOLECULAR AND CELLULAR BIOLOGY

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Small molecule–mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

(2009) Baozhi Chen et al.   Nature Chemical Biology

Activation of Wnt/β-catenin/Tcf signaling pathway in human astrocytomas

(2009) Gangadhara Reddy Sareddy et al.   NEUROCHEMISTRY INTERNATIONAL

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Downregulation of Wnt2 and β-catenin by siRNA suppresses malignant glioma cell growth

(2008) P Pu et al.   CANCER GENE THERAPY

β-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma

(2008) Shuang Yan et al.   CANCER LETTERS

Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation

(2008) Wenyan Lu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

ATRA-inhibited proliferation in glioma cells is associated with subcellular redistribution of β-catenin via up-regulation of Axin

(2008) Jianrong Lu et al.   JOURNAL OF NEURO-ONCOLOGY

Stabilized  -Catenin Functions through TCF/LEF Proteins and the Notch/RBP-J  Complex To Promote Proliferation and Suppress Differentiation of Neural Precursor Cells

(2008) T. Shimizu et al.   MOLECULAR AND CELLULAR BIOLOGY

A small-molecule inhibitor of Tcf/ -catenin signaling down-regulates PPAR  and PPAR  activities

(2008) S. Handeli et al.   MOLECULAR CANCER THERAPEUTICS

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of  -catenin

(2008) C. S. Cselenyi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA