[11C]DAC-PET for Noninvasively Monitoring Neuroinflammation and Immunosuppressive Therapy Efficacy in Rat Experimental Autoimmune Encephalomyelitis Model

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

(2010) Jerold Chun et al.   CLINICAL NEUROPHARMACOLOGY

The effects of Foxp3-expressing regulatory T cells expanded with CD28 superagonist antibody in DSS-induced mice colitis

(2010) Jiajie Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Current Views on the Roles of Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

(2010) Mohamed El-behi et al.   Journal of Neuroimmune Pharmacology

The Temporal Dynamics of Poststroke Neuroinflammation: A Longitudinal Diffusion Tensor Imaging-Guided PET Study with 11C-PK11195 in Acute Subcortical Stroke

(2010) A. Thiel et al.   JOURNAL OF NUCLEAR MEDICINE

Imaging of Peripheral-type Benzodiazepine Receptor in Tumor: Carbon Ion Irradiation Reduced the Uptake of a Positron Emission Tomography Ligand [11C]DAC in Tumor

(2010) Tomoteru YAMASAKI et al.   JOURNAL OF RADIATION RESEARCH

Visualization of early infarction in rat brain after ischemia using a translocator protein (18kDa) PET ligand [11C]DAC with ultra-high specific activity

(2010) Joji Yui et al.   NEUROIMAGE

In vivo imaging and quantitative analysis of TSPO in rat peripheral tissues using small-animal PET with [18F]FEDAC

(2010) Kazuhiko Yanamoto et al.   NUCLEAR MEDICINE AND BIOLOGY

Imaging of the translocator protein (18kDa) in rat brain after ischemia using [11C]DAC with ultra-high specific activity

(2010) Joji Yui et al.   SYNAPSE

Amelioration of experimental autoimmune encephalomyelitis by curcumin treatment through inhibition of IL-17 production

(2009) Lin Xie et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses

(2009) Dimitrios Papadopoulos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Reference Tissue Models and Blood-Brain Barrier Disruption: Lessons from (R)-[11C]PK11195 in Traumatic Brain Injury

(2009) H. Folkersma et al.   JOURNAL OF NUCLEAR MEDICINE

Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation

(2009) F. Chauveau et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation ofN-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat

(2009) Kazuhiko Yanamoto et al.   SYNAPSE

In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum

(2008) Hiroshi Toyama et al.   ANNALS OF NUCLEAR MEDICINE

Noninvasive imaging of macrophages in rheumatoid synovitis using11C-(R)-PK11195 and positron emission tomography

(2008) Conny J. van der Laken et al.   ARTHRITIS AND RHEUMATISM

Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers

(2008) Fabien Chauveau et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Imaging of Peripheral Benzodiazepine Receptor Expression as Biomarkers of Detrimental versus Beneficial Glial Responses in Mouse Models of Alzheimer's and Other CNS Pathologies

(2008) B. Ji et al.   JOURNAL OF NEUROSCIENCE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Differential regulation of central nervous system autoimmunity by TH1 and TH17 cells

(2008) Ingunn M Stromnes et al.   NATURE MEDICINE

Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair

(2008) Ming-Kai Chen et al.   PHARMACOLOGY & THERAPEUTICS