期刊
JOURNAL OF NEUROGENETICS
卷 22, 期 3, 页码 257-284出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/01677060802307755
关键词
Memory; engram; circuit; Drosophila; olfaction
资金
- National Science Council and Ministry of Education in Taiwan
One of the formidable challenges in modern neuroscience is to identify the physical basis of long-term memory (LTM) storagethe engram. Cellular and molecular experiments have suggested that the engram for a particular behavioral task is encoded as changes in synaptic structure and function, yet distributed in an unknown fashion across an ill-defined neural circuit or network. Accumulating genetic and circuitry information has provided some clues toward resolving this engram puzzle. This review will focus on recent discoveries of genes and circuits involved in the formation of olfactory-associated LTM in Drosophila.
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