Article
Obstetrics & Gynecology
Lizandra Moura Paravidine Sasaki, Bruno Ramalho de Carvalho, Adelino Amaral Silva, Alberto Moreno Zaconeta, Miriam da Silva Wanderley, Luiz Augusto Casulari Roxo da Motta, Adriana Lofrano-Porto
Summary: Selective LH deficiency has been described in both men and women, serving as a valuable model for studying the regulation of late-stage folliculogenesis and ovulation. A woman with LH deficiency due to a genetic mutation was successfully treated with individualized ovarian induction therapy, resulting in a healthy baby being born after an uneventful pregnancy. This case demonstrates that exogenous LH or hCG can effectively induce late-stage follicular development in women with deficient LH production or performance, once early follicular growth is assured by FSH.
HUMAN REPRODUCTION
(2021)
Article
Obstetrics & Gynecology
Li Chen, Qianwen Xi, Shutian Jiang, Yining Gao, Hui Long, Yao Wang, Yanping Kuang
Summary: This study compared the pregnancy and neonatal outcomes of patients triggered with GnRHa, hCG, and dual trigger in LE-IUI cycles. The study found that there was no significant difference in the clinical pregnancy rate between GnRHa and dual trigger compared to hCG trigger in LE-HMG IUI cycles. However, the miscarriage rate was lower in the GnRHa trigger group and higher in the dual trigger group compared to the hCG group. There were no significant differences in neonatal outcomes. Therefore, both GnRHa and dual trigger can be used to trigger ovulation in LE-HMG IUI cycles, but dual trigger must be used with caution.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Obstetrics & Gynecology
Xin Dai, Jingyi Li, Tian Fu, Xuefeng Long, Xiaoou Li, Ruiwen Weng, Yi Liu, Ling Zhang
Summary: This study aimed to compare the efficacy of sequential letrozole/HMG and letrozole alone in ovulation induction and pregnancy promotion among infertile women with PCOS. The results showed that the sequential treatment group had a higher ovulation rate and live birth rate compared to the letrozole group, with no significant adverse events.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Article
Fisheries
Teng Guo, Yanfeng Wang, Ping Jiang, Jun Li, Qinghua Liu, Liang Chi
Summary: This study explores the impact of photoperiod on the gonadal development and somatic growth of Atlantic salmon in recirculating aquaculture systems (RASs), specifically focusing on the role of microRNA-155 as a regulator in photoperiodic reproduction. The results show that longer photoperiods positively affect gonadal development in Atlantic salmon, as indicated by higher gonadosomatic index values and a higher proportion of mature fish. Additionally, the expression of hypothalamic miR-155 is influenced by the photoperiod and is involved in the regulation of photoperiod reproduction through targeting brain-derived neurotrophic factor (BDNF) and suppressing gonadal axis-related genes.
Review
Endocrinology & Metabolism
Harvey Stevenson, Samuel Bartram, Mikaela Maria Charalambides, Sruthi Murthy, Theo Petitt, Anjali Pradeep, Owen Vineall, Ikenna Abaraonye, Amelia Lancaster, Kanyada Koysombat, Bijal Patel, Ali Abbara
Summary: Feedback from oestradiol is mediated by KP-neurons in the hypothalamus and RP3V regions, regulating the physiological menstrual cycle. Hypothalamic KP-neurons control GnRH pulsatility through negative feedback, while RP3V KP-neurons induce LH surge and ovulation through positive feedback.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Fisheries
Masataka Ishii, Tatsuya Unuma, Akio Masadate, Hiroshi Hoshikawa, Kazuhiro Takahashi, Shinichi Kosaka, Atsunori Masuda, Katsusuke Murakami
Summary: This study investigated the effects of photoperiod control on promoting gonadal maturation in Strongylocentrotus intermedius. It was found that accelerated photoperiods can advance maturation by 2-3 months and the collected gametes can develop normally into juveniles.
Article
Agriculture, Dairy & Animal Science
I. T. El-Ratel, A. E. Abdel-Khalek, Sara F. Fouda
Summary: The results of the experiments showed that injection of eCG with GnRH or hCG significantly increased reproductive efficiency and progesterone concentration in rabbit does, while injection of eCG on day 5 post-AI improved follicle number and reproductive efficiency.
TROPICAL ANIMAL HEALTH AND PRODUCTION
(2021)
Review
Endocrinology & Metabolism
Yong Zhu
Summary: Metalloproteases, including Mmp, Adam, Adamts, and Timp, play crucial roles in ovulation and gonad formation processes. These enzymes are regulated by hormones like LH and progestin, and are involved in PGC migration, germ cell development, and sex determination in vertebrates. More research is needed to fully understand their functions and mechanisms in these processes.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2021)
Review
Plant Sciences
Joshua M. Gendron, Dorothee Staiger
Summary: Photoperiod-measuring mechanisms allow organisms to anticipate seasonal changes, ensuring reproduction and growth at appropriate times. This review provides historical and modern context to studies of plant photoperiodism, including the development of theoretical models and recent molecular genetic research in Arabidopsis and rice. It also discusses the implications of photoperiod transcriptomics for understanding gene regulatory networks and the discovery of noncanonical photoperiod-measuring systems in plants.
ANNUAL REVIEW OF PLANT BIOLOGY
(2023)
Article
Endocrinology & Metabolism
Elizabeth M. Simpson, Iain J. Clarke, Christopher J. Scott, Cyril P. Stephen, Alexandra Rao, Allan J. Gunn
Summary: This study investigates the effect of intravenous infusion of exendin-4 on luteinising hormone (LH) secretion in sheep. The results show that exendin-4 increases plasma LH concentrations and LH peripheral pulse amplitude, without affecting inter-pulse interval or timing of the preovulatory LH surge. Additionally, the study reveals that endogenous GLP-1, likely derived from the hindgut, may act systemically to stimulate LH secretion.
JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Reproductive Biology
Sarah L. Whiteley, Robert D. McCuaig, Clare E. Holleley, Sudha Rao, Arthur Georges
Summary: This study utilized automated staining and imaging platforms to provide immunofluorescent data for a reptile species with temperature-induced sex reversal, showing differences in protein dynamics between males, females, and sex-reversed females. The characterization of tissue-specific expression and cellular localization patterns of chromatin modifiers, histone marks, and environmental response proteins in the adult gonads of a dragon lizard provides new insights into the molecular characteristics of sex determination and maintenance.
BIOLOGY OF REPRODUCTION
(2022)
Article
Reproductive Biology
Lais Reis Carvalho, Luiz Manoel Souza Simoes, Lucas Araujo Lemos, Matheus Pedroso Vicente, Samuel Volpe Souza, Walter Antonio Goncales Junior, Bruna Martins Guerreiro, Bruno Gonzales de Freitas, Jose Camisao de Souza, Jose Nelio Sousa Sales
Summary: The effectiveness of using different doses of injectable progesterone (P4i) in place of progesterone-releasing intravaginal devices in Bos indicus cows was evaluated in this study. The results indicate that replacing the intravaginal devices with long-acting progesterone injections negatively affects the conception rate in cows.
Article
Biotechnology & Applied Microbiology
Chongqing Wang, Xiang Luo, Huan Qin, Chun Zhao, Li Yang, Tingting Yu, Yuxin Zhang, Xu Huang, Xidan Xu, Qinbo Qin, Shaojun Liu
Summary: This study explored the fertility-related candidate genes in autotriploid Carassius auratus and identified 6 hub genes (MYC, SOX2, BMP4, GATA4, PTEN, and BMP2) related to female fertility, as well as 2 hub genes (TP53 and FGF2) associated with male sterility. The findings provide valuable insights into reproduction and breeding in triploid fish, establishing autotriploid fish as an ideal model for studying reproductive traits.
Article
Environmental Sciences
Silvia Lourenco, Ricardo Jose, Pedro Neves, Andre Gois, Nereida Cordeiro, Carlos Andrade, Claudia Ribeiro
Summary: This study evaluated the population and market characteristics of S. granularis in the oligotrophic and narrow insular shelf of Madeira archipelago. The study found that S. granularis mainly inhabit shallow waters and breakwaters, with encrusting algae and erect brown macroalgae as their primary habitat. The population has a long reproductive season, high gonad quality, and nutritional value, with September to November being the preferred harvesting season.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Multidisciplinary Sciences
Dallas R. Taylor, Michael Prorock, Brandon J. Horvath, James T. Brosnan
Summary: Turfgrasses are vital components of urban greenspaces, but the prolific seed producer Poa annua poses a significant threat to ecosystem services. Field research indicated that fluctuations in soil temperature and rainfall have a considerable impact on the emergence patterns of Poa annua seedlings, guiding optimal intervention timing.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Akiko Takahashi, M. Sadiqul Islam, Hideki Abe, Kataaki Okubo, Yasuhisa Akazome, Takeshi Kaneko, Hiroyuki Hioki, Yoshitaka Oka
JOURNAL OF COMPARATIVE NEUROLOGY
(2016)
Article
Endocrinology & Metabolism
Masaharu Hasebe, Yoshitaka Oka
Editorial Material
Biochemistry & Molecular Biology
Motoaki Seki
PLANT MOLECULAR BIOLOGY
(2019)
Article
Multidisciplinary Sciences
Daichi Kayo, Buntaro Zempo, Soma Tomihara, Yoshitaka Oka, Shinji Kanda
SCIENTIFIC REPORTS
(2019)
Review
Zoology
Chie Umatani, Yoshitaka Oka
ZOOLOGICAL LETTERS
(2019)
Article
Endocrinology & Metabolism
Daichi Kayo, Yoshitaka Oka, Shinji Kanda
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2020)
Article
Physiology
Yoichi Kasahara, Masataka Narukawa, Yoshiro Ishimaru, Shinji Kanda, Chie Umatani, Yasunori Takayama, Makoto Tominaga, Yoshitaka Oka, Kaori Kondo, Takashi Kondo, Ayako Takeuchi, Takumi Misaka, Keiko Abe, Tomiko Asakura
Summary: The study reveals that TMC4 acts as a chloride channel responding to high-concentration NaCl in the oral cavity, facilitating the permeation of organic anions and showing a weaker glossopharyngeal nerve response in Tmc4-deficient mice compared to wild-type littermates.
JOURNAL OF PHYSIOLOGICAL SCIENCES
(2021)
Article
Multidisciplinary Sciences
Soma Tomihara, Yoshitaka Oka, Shinji Kanda
Summary: Behavioral analysis plays a crucial role in biological studies, but manual behavioral recordings are laborious and prone to human-errors. By establishing an open-source behavioral recording system using Raspberry Pi, automated video-recording and file-sorting are achieved, reducing human errors significantly. Additionally, with the development of an Excel macro, behavioral annotation becomes easier and more efficient.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Chie Umatani, Nagisa Yoshida, Eri Yamamoto, Yasuhisa Akazome, Yasutaka Mori, Shinji Kanda, Kataaki Okubo, Yoshitaka Oka
Summary: Animals use multiple sensory cues to perform sexual behaviors, but the neural mechanisms behind integrating these cues and regulating motivation for sexual behaviors are not well understood. This study focuses on TN-GnRH neurons, which co-express NPFF and GnRH3, and demonstrates their role in modulating certain neuronal circuits for controlling behavioral motivation. Specifically, NPFF activates neurons in the preoptic area, leading to an increase in motivation for male sexual behaviors. These findings contribute to our understanding of the functional significance of peptidergic neuromodulation in response to sensory information from the external environments.
Article
Endocrinology & Metabolism
Kana Ikegami, Sho Kajihara, Chie Umatani, Mikoto Nakajo, Shinji Kanda, Yoshitaka Oka
Summary: Using a non-mammalian model of medaka, it was found that 17 beta-estradiol could promote the upregulation of GnRH1 neuronal activity, triggering the GnRH surge, and the combined action of estrogen and time signals is crucial for triggering ovulation at the appropriate time.
JOURNAL OF NEUROENDOCRINOLOGY
(2022)
Review
Endocrinology & Metabolism
Satoshi Ogawa, Naoyuki Yamamoto, Hanako Hagio, Yoshitaka Oka, Ishwar S. Parhar
Summary: Three paralogous genes for GnRH and GnRH receptors exist in non-mammalian vertebrates. The migration of GnRH neurons in the brain is evolutionally conserved across different species. Each GnRH system has distinctive anatomical and physiological characteristics, and functions differently based on their origin and expression patterns.
JOURNAL OF NEUROENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Yukiko Kikuchi, Towako Hiraki-Kajiyama, Mikoto Nakajo, Chie Umatani, Shinji Kanda, Yoshitaka Oka, Keisuke Matsumoto, Hitoshi Ozawa, Kataaki Okubo
Article
Endocrinology & Metabolism
Buntaro Zempo, Tomomi Karigo, Shinji Kanda, Yasuhisa Akazome, Yoshitaka Oka
Article
Endocrinology & Metabolism
Mikoto Nakajo, Shinji Kanda, Tomomi Karigo, Akiko Takahashi, Yasuhisa Akazome, Yoshihisa Uenoyama, Makito Kobayashi, Yoshitaka Oka
Article
Endocrinology & Metabolism
Chie Umatani, Yoshitaka Oka