Article
Neurosciences
Seung-Goo Kim, Tobias Overath, William Sedley, Sukhbinder Kumar, Sundeep Teki, Yukiko Kikuchi, Roy Patterson, Timothy D. Griffiths
Summary: The study recorded neural responses in human participants to different types of pitch-evoking stimuli, finding cortical sensitivity to temporal regularity relevant to pitch in the Heschl's sulcus, which was consistent across different types of pitch-relevant stimuli.
Article
Neurosciences
Erik C. Brown, Brittany Stedelin, Seiji Koike, Ahmed M. Raslan, Nathan R. Selden
Summary: The study found that superior temporal sites exhibit sustained responses to both forward and reverse speech during auditory processing, and the response to paired stimuli is influenced by relative salience, along with feedback loops involving linguistic processing and articulation.
Article
Neurosciences
Hohyun Cho, Yvonne M. Fonken, Markus Adamek, Richard Jimenez, Jack J. Lin, Gerwin Schalk, Robert T. Knight, Peter Brunner
Summary: By assessing the response to omitted expected sounds, we found that high-frequency band activity (HFA) overlaps with auditory-active regions in the posterior superior temporal gyrus (STG), suggesting its central role in implementing predictions in the auditory environment.
Article
Neurosciences
Jan Benner, Julia Reinhardt, Markus Christiner, Martina Wengenroth, Christoph Stippich, Peter Schneider, Maria Blatow
Summary: We used co-registration of fMRI and MEG to investigate the temporal segregation of human auditory responses in musicians with and without absolute pitch. Our findings reveal a characteristic temporal hierarchy of auditory regions in relation to specific auditory abilities, supporting the hypothesis of serial processing from nonhuman studies.
Article
Neurosciences
Zhishuai Jin, Sizhu Huyang, Lichen Jiang, Yajun Yan, Ming Xu, Jinyu Wang, Qixiong Li, Daxing Wu
Summary: The study revealed that individuals with congenital amusia exhibit increased interhemispheric functional connectivity in the posterior part of the default mode network, particularly in the posterior superior temporal gyrus and posterior cingulate cortex, which were negatively correlated with music perception ability. These findings suggest that the immature state of the default mode network may serve as a reliable neural marker for amusia.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Psychiatry
Tsutomu Takahashi, Daiki Sasabayashi, Yoichiro Takayanagi, Atsushi Furuichi, Mikio Kido, Mihoko Nakamura, Tien Viet Pham, Haruko Kobayashi, Kyo Noguchi, Michio Suzuki
Summary: The study revealed that first-episode schizophrenia patients showed lower gray matter volumes in the HG and PT compared to healthy controls, and had a higher prevalence of duplicated HG patterns. Additionally, different HG duplication patterns were associated with clinical symptoms in patients with schizophrenia.
SCHIZOPHRENIA RESEARCH
(2021)
Article
Neurosciences
Tsutomu Takahashi, Daiki Sasabayashi, Murat Yucel, Sarah Whittle, Valentina Lorenzetti, Mark Walterfang, Michio Suzuki, Christos Pantelis, Gin S. Malhi, Nicholas B. Allen
Summary: This study aimed to investigate the disease specificity of altered Heschl's gyrus (HG) patterns in schizophrenia by examining cohorts of bipolar disorder (BD) and major depressive disorder (MDD). The results showed a significantly higher prevalence of duplicated HG in BD patients compared to controls, indicating partial overlap between BD and schizophrenia in neurodevelopmental pathology associated with gyral formation. However, no significant difference in HG patterns was found between MDD patients and controls, suggesting a distinct contribution of HG patterns to the phenomenology of MDD.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Helbert de Oliveira Manduca Palmiero, Eduardo Carvalhal Ribas, Manoel Jacobsen Teixeira, Eberval Gadelha Figueiredo
Summary: Posterior temporal craniotomy allows for the exposure of Heschl's gyrus, which can be used as a natural corridor to approach deep brain structures. Anatomic measurements from human cadaver heads showed that the mean distance between the keyhole and Heschl's gyrus was 61.7 mm, the mean distance between the stephanion to Heschl's gyrus was 40.8 mm, and the mean distance between the temporal lobe and Heschl's gyrus was 54.9 mm. Through a posterior temporal craniotomy, Heschl's gyrus can be identified and used as a pathway to access the internal capsule, ventricular atrium, and lateral thalamus.
ACTA NEUROCHIRURGICA
(2023)
Article
Neurosciences
Dongxu Liu, Yichen Chang, Guangyan Dai, Zhiqiang Guo, Jeffery A. Jones, Tingni Li, Xi Chen, Mingyun Chen, Jingting Li, Xiuqin Wu, Peng Liu, Hanjun Liu
Summary: This study investigated the neurobehavioral changes in vocal pitch regulation in response to altered auditory feedback by selectively stimulating the left or right pSTG with continuous theta burst stimulation (c-TBS). The results showed that c-TBS over the right pSTG led to smaller vocal compensations for pitch perturbations accompanied by changes in cortical N1 and P2 responses. Enhanced P2 responses were found to be correlated with suppressed vocal compensations. However, these effects were not observed when c-TBS was applied to the left pSTG. These findings provide evidence for a causal relationship between the right pSTG and auditory-motor integration in vocal pitch regulation.
Article
Health Care Sciences & Services
Tsutomu Takahashi, Daiki Sasabayashi, Yoichiro Takayanagi, Atsushi Furuichi, Mikio Kido, Tien Viet Pham, Haruko Kobayashi, Kyo Noguchi, Michio Suzuki
Summary: This study found a high prevalence of duplicated HG patterns in patients with schizophrenia and schizotypal disorder, with no significant difference between the two groups. Different HG gyrification patterns may be associated with symptom severity and antipsychotic medication dosage in patients.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Neurosciences
Linyan Liu, Dongxue Liu, Tingting Guo, John W. Schwieter, Huanhuan Liu
Summary: In real-life communication, individuals tend to seek more praise while avoiding criticism. Semantics is crucial for conveying information, with subtle differences in semantic access between native and foreign languages. Investigating rule learning in different languages, this study highlights the importance of semantics in the process. The findings suggest that individuals are more motivated to learn and adhere to rules in their native language, with distinct neural mechanisms involved.
Article
Neurosciences
Alexandra Korzeczek, Annika Primassin, Alexander Wolff von Gudenberg, Peter Dechent, Walter Paulus, Martin Sommer, Nicole E. Neef
Summary: Improved fluency in persons who stutter after one-year fluency-shaping therapy is accompanied by increased connectivity within the sensorimotor integration network, with strengthened connections between the left inferior frontal gyrus and key brain regions involved in speech production. This therapy-associated neural remediation is based on enhancing the command-to-execution pathway and auditory-to-motor coupling.
Article
Neurosciences
Bahar Khalighinejad, Prachi Patel, Jose L. Herrero, Stephan Bickel, Ashesh D. Mehta, Nima Mesgarani
Summary: Heschl's gyrus (HG) plays a crucial role in speech perception by processing and transforming acoustic features. Experimental findings indicate a gradient of change within HG from posteromedial to anterolateral regions, with decreased frequency and temporal modulation tuning but increased phonemic representation and response latency.
Article
Neurosciences
Jason H. Y. Yeung, Thulani H. Palpagama, Oliver W. G. Wood, Clinton Turner, Henry J. Waldvogel, Richard L. M. Faull, Andrea Kwakowsky
Summary: Alzheimer's disease is characterized by the presence of amyloid-beta plaques and neurofibrillary tangles. Glutamate dysregulation and excitotoxicity are thought to play a major role in the pathogenesis of AD. Studies have shown alterations in the expression of EAAT2 in multiple brain regions in AD, suggesting potential disruptions in glutamate recycling and homeostasis.
FRONTIERS IN CELLULAR NEUROSCIENCE
(2021)
Article
Behavioral Sciences
Daegyeom Kim, Joo Young Lee, Byeong Chang Jeong, Ja-Hye Ahn, Johanna Inhyang Kim, Eun Soo Lee, Hyuna Kim, Hyun Ju Lee, Cheol E. Han
Summary: This study investigated structural brain connectivity in low-functioning ASD preschool-aged children using diffusion magnetic resonance imaging and graph theory. The findings revealed increased nodal strength in the right Heschl's gyrus and right inferior temporal gyrus, which were positively associated with autistic symptoms, suggesting potential regional biomarkers for detecting low-functioning ASD in preschool-aged children.
