Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington's disease

Chemoprevention of Prostate Cancer by D,L-Sulforaphane Is Augmented by Pharmacological Inhibition of Autophagy

(2013) A. R. Vyas et al.   CANCER RESEARCH

Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease

(2013) Fabiana Morroni et al.   NEUROTOXICOLOGY

Impaired Mitochondrial Dynamics and Nrf2 Signaling Contribute to Compromised Responses to Oxidative Stress in Striatal Cells Expressing Full-Length Mutant Huntingtin

(2013) Youngnam N. Jin et al.   PLoS One

Amelioration of Alzheimer’s disease by neuroprotective effect of sulforaphane in animal model

(2012) Hyunjin Vincent Kim et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Crosstalk between Nrf2 and the proteasome: Therapeutic potential of Nrf2 inducers in vascular disease and aging

(2012) Sarah J. Chapple et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calretinin interacts with huntingtin and reduces mutant huntingtin-caused cytotoxicity

(2012) Gaofeng Dong et al.   JOURNAL OF NEUROCHEMISTRY

Mass spectrometric identification of novel posttranslational modification sites in Huntingtin

(2012) Gaofeng Dong et al.   PROTEOMICS

Modeling Pathogenesis of Huntington’s Disease with Inducible Neuroprogenitor Cells

(2011) G. Dong et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Prothymosin-α Interacts with Mutant Huntingtin and Suppresses Its Cytotoxicity in Cell Culture

(2011) Gaofeng Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons

(2011) Qiuli Liang et al.   Molecular Neurodegeneration

Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice

(2011) John D. Clarke et al.   PHARMACEUTICAL RESEARCH

Enhancement of proteasome function by PA28α overexpression protects against oxidative stress

(2010) Jie Li et al.   FASEB JOURNAL

Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Up-regulation of Hsp27

(2010) Nanqin Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasomal dysfunction in aging and Huntington disease

(2010) Xiao-Jiang Li et al.   NEUROBIOLOGY OF DISEASE

Pharmacokinetics and Pharmacodynamics of Broccoli Sprouts on the Suppression of Prostate Cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mice: Implication of Induction of Nrf2, HO-1 and Apoptosis and the Suppression of Akt-dependent Kinase Pathway

(2009) Young-Sam Keum et al.   PHARMACEUTICAL RESEARCH

A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome

(2008) Jinbao Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Intracellular degradation of misfolded proteins in polyglutamine neurodegenerative diseases

(2008) Xiang Li et al.   BRAIN RESEARCH REVIEWS