AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway

Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency

(2012) Eirini Meimaridou et al.   NATURE GENETICS

Mitochondrial Thiols in Antioxidant Protection and Redox Signaling: Distinct Roles for Glutathionylation and Other Thiol Modifications

(2011) Michael P. Murphy   ANTIOXIDANTS & REDOX SIGNALING

Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells

(2011) Fei Yin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons

(2011) F. H. Sterky et al.   HUMAN MOLECULAR GENETICS

Mammalian NADH:ubiquinone oxidoreductase (Complex I) and nicotinamide nucleotide transhydrogenase (Nnt) together regulate the mitochondrial production of H2O2—Implications for their role in disease, especially cancer

(2011) Simon P. J. Albracht et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Altered Postnatal Development of Cortico—Hippocampal Neuronal Electric Activity in Mice Deficient for the Mitochondrial Aspartate—Glutamate Transporter

(2011) Marta Gómez-Galán et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Striatum Is Highly Susceptible to Mitochondrial Oxidative Phosphorylation Dysfunctions

(2011) A. M. Pickrell et al.   JOURNAL OF NEUROSCIENCE

Deficiency of the mitochondrial transporter of aspartate/glutamate aralar/AGC1 causes hypomyelination and neuronal defects unrelated to myelin deficits in mouse brain

(2011) Milagros Ramos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety

(2011) Larry S Zweifel et al.   NATURE NEUROSCIENCE

Investigating anxiety and depressive-like phenotypes in genetic mouse models of serotonin depletion

(2011) Sebastian P. Fernandez et al.   NEUROPHARMACOLOGY

The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease

(2011) D.J. Surmeier et al.   NEUROSCIENCE

Reactive Oxygen Species Originating From Mitochondria Regulate the Cardiac Sodium Channel

(2010) Man Liu et al.   CIRCULATION RESEARCH

Brain Glutamine Synthesis Requires Neuronal-Born Aspartate as Amino Donor for Glial Glutamate Formation

(2010) Beatriz Pardo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Genetic Animal Models of Parkinson's Disease

(2010) Ted M. Dawson et al.   NEURON

Slc25a12 Disruption Alters Myelination and Neurofilaments: A Model for a Hypomyelination Syndrome and Childhood Neurodevelopmental Disorders

(2009) Takeshi Sakurai et al.   BIOLOGICAL PSYCHIATRY

Low levels of citrin (SLC25A13) expression in adult mouse brain restricted to neuronal clusters

(2009) Laura Contreras et al.   JOURNAL OF NEUROSCIENCE RESEARCH

AGC1 Deficiency Associated with Global Cerebral Hypomyelination

(2009) Rolf Wibom et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dopamine Signaling in the Dorsal Striatum Is Essential for Motivated Behaviors

(2008) Richard D. Palmiter   Annals of the New York Academy of Sciences

Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease

(2008) Derek A. Drechsel et al.   FREE RADICAL BIOLOGY AND MEDICINE

VMAT2 and dopamine neuron loss in a primate model of Parkinson’s disease

(2008) Ming-Kai Chen et al.   JOURNAL OF NEUROCHEMISTRY

Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice

(2008) L. Chen et al.   JOURNAL OF NEUROSCIENCE

A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function

(2008) J. D. Cahoy et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial Complex I Inhibitor Rotenone Inhibits and Redistributes Vesicular Monoamine Transporter 2 via Nitration in Human Dopaminergic SH-SY5Y Cells

(2008) M. Watabe et al.   MOLECULAR PHARMACOLOGY

Neurotrophic and neurotoxic effects of nitric oxide on fetal midbrain cultures

(2003) S. Canals et al.   JOURNAL OF NEUROCHEMISTRY