Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons

Precursor of Brain-derived Neurotrophic Factor (proBDNF) Forms a Complex with Huntingtin-associated Protein-1 (HAP1) and Sortilin That Modulates proBDNF Trafficking, Degradation, and Processing

(2011) Miao Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Heparin and Enoxaparin on APP Processing and Aβ Production in Primary Cortical Neurons from Tg2576 Mice

(2011) Hao Cui et al.   PLoS One

Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia

(2010) Izabela Rasmussen et al.   BMC IMMUNOLOGY

Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing

(2010) Hirokazu Okada et al.   FASEB JOURNAL

Huntingtin-associated Protein-1 Deficiency in Orexin-producing Neurons Impairs Neuronal Process Extension and Leads to Abnormal Behavior in Mice

(2010) Yung-Feng Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Delivery of GABAARs to Synapses Is Mediated by HAP1-KIF5 and Disrupted by Mutant Huntingtin

(2010) Alison E. Twelvetrees et al.   NEURON

Regulation of Amyloid Precursor Protein Processing by the Beclin 1 Complex

(2010) Philipp A. Jaeger et al.   PLoS One

Huntingtin associated protein 1 and its functions

(2010) Linda Lin-yan Wu et al.   Cell Adhesion & Migration

Neuronal protein trafficking associated with Alzheimer disease

(2010) Bor Luen Tang   Cell Adhesion & Migration

Essential Role of Hrs in Endocytic Recycling of Full-length TrkB Receptor but Not Its Isoform TrkB.T1

(2009) Shu-Hong Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntingtin-associated Protein-1 Interacts with Pro-brain-derived Neurotrophic Factor and Mediates Its Transport and Release

(2009) Linda Lin-yan Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism underlying activity-dependent insertion of TrkB into the neuronal surface

(2009) L. Zhao et al.   JOURNAL OF CELL SCIENCE

Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease

(2009) S. Peng et al.   JOURNAL OF NEUROSCIENCE

APP Anterograde Transport Requires Rab3A GTPase Activity for Assembly of the Transport Vesicle

(2009) A. Szodorai et al.   JOURNAL OF NEUROSCIENCE

The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation

(2009) Y. Wang et al.   LEARNING & MEMORY

Retromer Sorting

(2008) Scott A. Small   ARCHIVES OF NEUROLOGY

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A bi-directional carboxypeptidase E-driven transport mechanism controls BDNF vesicle homeostasis in hippocampal neurons

(2008) Joshua J. Park et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics—Relevance for Alzheimer's disease

(2008) Thorsten Müller et al.   PROGRESS IN NEUROBIOLOGY