Pituitary adenylate cyclase-activating peptide induces long-lasting neuroprotection through the induction of activity-dependent signaling via the cyclic AMP response element-binding protein-regulated transcription co-activator 1

The influence of synaptic activity on neuronal health

(2011) Karen FS Bell et al.   CURRENT OPINION IN NEUROBIOLOGY

A Signaling Cascade of Nuclear Calcium-CREB-ATF3 Activated by Synaptic NMDA Receptors Defines a Gene Repression Module That Protects against Extrasynaptic NMDA Receptor-Induced Neuronal Cell Death and Ischemic Brain Damage

(2011) S.-J. Zhang et al.   JOURNAL OF NEUROSCIENCE

Pituitary adenylate cyclase activating polypeptide in the retina: focus on the retinoprotective effects

(2010) T. Atlasz et al.   Annals of the New York Academy of Sciences

Neuronal Activity Controls the Antagonistic Balance Between Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α and Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptors in Regulating Antioxidant Defenses

(2010) Francesc X. Soriano et al.   ANTIOXIDANTS & REDOX SIGNALING

VIP, CRF, and PACAP Act at Distinct Receptors to Elicit Different cAMP/PKA Dynamics in the Neocortex

(2010) Emilie Hu et al.   CEREBRAL CORTEX

Synaptic NMDAR activity suppresses FOXO1 expression via a cis-acting FOXO binding site: FOXO1 is a FOXO target gene

(2010) Bashayer Mubarak et al.   Channels

Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity

(2010) F. Leveille et al.   JOURNAL OF NEUROSCIENCE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

(2009) Giles E. Hardingham   BIOCHEMICAL SOCIETY TRANSACTIONS

TORC1 Regulates Activity-Dependent CREB-Target Gene Transcription and Dendritic Growth of Developing Cortical Neurons

(2009) S. Li et al.   JOURNAL OF NEUROSCIENCE

Signaling pathways in PACAP regulation of VIP gene expression in human neuroblastoma cells

(2009) Birgitte Falktoft et al.   NEUROPEPTIDES

Pituitary Adenylate Cyclase-Activating Polypeptide and Its Receptors: 20 Years after the Discovery

(2009) D. Vaudry et al.   PHARMACOLOGICAL REVIEWS

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Modulation of AMPA receptor-mediated ion current by pituitary adenylate cyclase-activating polypeptide (PACAP) in CA1 pyramidal neurons from rat hippocampus

(2008) L. Costa et al.   HIPPOCAMPUS

Elevated Synaptic Activity Preconditions Neurons against anin VitroModel of Ischemia

(2008) Joseph S. Tauskela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibitory Effect of PACAP on Caspase Activity in Neuronal Apoptosis: A Better Understanding Towards Therapeutic Applications in Neurodegenerative Diseases

(2008) Agnieszka Dejda et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Role of PACAP in Ischemic Neural Death

(2008) Hirokazu Ohtaki et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione

(2008) Francesc X. Soriano et al.   JOURNAL OF NEUROCHEMISTRY

Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand

(2008) F. X. Soriano et al.   JOURNAL OF NEUROSCIENCE

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

Neuroprotective effects of PACAP27 in mice model of Parkinson’s disease involved in the modulation of KATP subunits and D2 receptors in the striatum

(2008) Gang Wang et al.   NEUROPEPTIDES

VPAC and PAC receptors: From ligands to function

(2008) Louise Dickson et al.   PHARMACOLOGY & THERAPEUTICS