Article
Cell Biology
Fuad J. Naser, Madelyn M. Jackstadt, Ronald Fowle-Grider, Jonathan L. Spalding, Kevin Cho, Ethan Stancliffe, Steven R. Doonan, Eva T. Kramer, Lijun Yao, Bradley Krasnick, Li Ding, Ryan C. Fields, Charles K. Kaufman, Leah P. Shriver, Stephen L. Johnson, Gary J. Patti
Summary: The study revealed that melanoma consumes significantly more glucose than other tissues and the tumor liver alanine cycle plays a crucial role in maintaining circulating glucose levels in diseased animals. Inhibition of this cycle reduced tumor burden, highlighting the importance of metabolic crosstalk between tumors and distant tissues.
Article
Biodiversity Conservation
Laura Castaneda-Gomez, Kate Lajtha, Richard Bowden, Fathima Nahidha Mohammed Jauhar, Juan Jia, Xiaojuan Feng, Myrna J. Simpson
Summary: Forest ecosystems as global soil carbon reservoirs are affected by climate change factors that change carbon inputs. This study integrated molecular composition data sets of soil organic matter and microbial communities to investigate the effects of detrital input and removal treatments on forest soil carbon dynamics. The results showed that long-term litter additions did not increase soil carbon content, while litter reductions negatively impacted soil carbon concentrations. This highlights the sensitivity of soil carbon biogeochemistry to changes in litter deposition.
GLOBAL CHANGE BIOLOGY
(2023)
Article
Food Science & Technology
Atique Ahmed Behan, Muhammad Tayyab Akhtar, Teck Chwen Loh, Sharida Fakurazi, Ubedullah Kaka, Azira Muhamad, Anjas Asmara Samsudin
Summary: The addition of rumen bypass fats can significantly alter the fatty acid composition of meat, increasing unsaturated fatty acids and reducing saturated fatty acids. Additionally, in some treatments, meat pH levels may increase.
Review
Biochemistry & Molecular Biology
Jones Gyamfi, Jinyoung Kim, Junjeong Choi
Summary: Cancer is not only a genetic disease but also a result of metabolic dysregulation. Metabolic alterations in cancer cells, including key changes in glucose, glutamine, and fatty acid metabolism, are more common among different subtypes and types of cancer. Recognizing cancer as a metabolic disorder can reveal important diagnostic and treatment markers.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Environmental Sciences
Meiling Man, Derek Pierson, Ricky Chiu, Maryam Tabatabaei Anaraki, Lori VandenEnden, RenXi Ye, Kate Lajtha, Myrna J. Simpson
Summary: Global environmental change is affecting the inputs of plant residues into soil, but how this impacts soil carbon biogeochemistry remains unclear. This study found that different detrital inputs can alter the biogeochemistry and composition of soil organic matter at a molecular level. Above-ground litter has a greater influence on soil carbon cycling than below-ground inputs.
Review
Medicine, Research & Experimental
John L. Caniglia, Anvesh Jalasutram, Swapna Asuthkar, Joseph Sahagun, Simon Park, Aditya Ravindra, Andrew J. Tsung, Maheedhara R. Guda, Kiran K. Velpula
Summary: Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults with a median survival of just 15 months; Researchers are focusing on targeting glucose metabolism to meet the increased demand for replication and progression in GBM; Despite the limited therapeutic interventions specifically targeting metabolic pathways in GBM, further insight is hoped to be gained through this review to develop novel treatment modalities.
Article
Food Science & Technology
Zhichao Xiao, Wangang Zhang, Hongtao Yang, Ziyu Yan, Changrong Ge, Guozhou Liao, Huawei Su
Summary: This study aimed to compare the content of main flavor substances in raw meat and chicken soup between two Chinese native chickens and one typical commercial broiler. The results showed that the Chinese native chickens had higher levels of flavor compounds in their meat, while the commercial broiler had higher levels in its chicken soup.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sai Man Cheung, Ehab Husain, Vasiliki Mallikourti, Yazan Masannat, Steven Heys, Jiabao He
Summary: Lipid composition may serve as a biomarker for studying lymphovascular invasion in breast cancer.
EUROPEAN RADIOLOGY
(2021)
Article
Veterinary Sciences
Olivia Chiu, Moran Tal, Abbinash Sanmugam, Myriam Hesta, Diego E. Gomez, Jeffrey Scott Weese, Adronie Verbrugghe
Summary: This study investigated the effect of ambient temperature exposure on microbial-derived metabolites of feline fecal samples. The results showed that short-term (up to 4 h) exposure to ambient temperature seems to be acceptable.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Cardiac & Cardiovascular Systems
Danyao Jin, Eirini Trichia, Nazrul Islam, Sarah Lewington, Ben Lacey
Summary: This study investigates the independent associations of circulating fatty acids with the risk of coronary heart disease (CHD) through a large-scale epidemiological study. The results show that saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) are positively associated with CHD risk, while omega-3 polyunsaturated fatty acids (PUFA) are inversely associated with CHD risk. There is no strong evidence of an association between omega-6 PUFA and CHD risk.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Agriculture, Dairy & Animal Science
Anamaria Hanganu, Nicoleta-Aurelia Chira
Summary: This study investigated the limitations of the current method for determining the fatty acid profile of milk fats from proton nuclear magnetic resonance data. It was found that the current approach may lead to misclassification, and new descriptors based on proton nuclear magnetic resonance were proposed for fraud detection.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Chemistry, Applied
Weizhu Chen, Wenhui Jin, Yiping Zhang, Hua Fang, Hui Chen, Hong Zhuan, Xiaoyan Huang
Summary: Certified reference materials (CRMs) with high accuracy and traceability are essential for validating analytical methods and calibrating equipment. This study developed purity CRMs for four polyunsaturated fatty acids esters and determined their purity values using quantitative nuclear magnetic resonance and mass balance approaches, demonstrating high precision and reliability.
Article
Medicine, General & Internal
Julius Honecker, Stefan Ruschke, Claudine Seeliger, Samantha Laber, Sophie Strobel, Priska Proll, Christoffer Nellaker, Cecilia M. Lindgren, Ulrich Kulozik, Josef Ecker, Dimitrios C. Karampinos, Melina Claussnitzer, Hans Hauner
Summary: This study provides insights into the transcriptomic and FA landscape associated with adipocyte hypertrophy in adipose tissue. The development of non-invasive techniques, such as MRS, allows for the assessment of adipocyte size and FA composition in a clinical context, improving the phenotyping of adipose tissue in metabolic diseases.
Article
Chemistry, Inorganic & Nuclear
Kazuo Eda, Masahiko Akune, Chie Yasuma, Hiroki Hotta, Toshiyuki Osakai, Takahito Nakajima
Summary: The study investigated the occupancy of central vacancies in Keggin-type iso-polyoxotungstate anions by protons, and found that the vacancies can be fully occupied by four protons. The thermochemistry analysis revealed that [HnW12O40]((8-n)-) was more stable than H-1[Hn-1W12O40]((8-n)-), with a rate constant of 3.1 x 10(1) s(-1) for proton transfer at T = 298.15 K from H-1[H3W12O40](4-) to [H4W12O40](4-).
INORGANIC CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Katarzyna Dabrowska, Katarzyna Skowronska, Mariusz Popek, Jan Albrecht, Magdalena Zielinska
Summary: The study found that dysregulation of the SN1 transporter by ammonia in astrocytes involves activation of Nrf2, but does not require the formation of the Sp1-Nrf2 complex.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Pei-Yang Gao, Ya-Nan Ou, Yi-Ming Huang, Zhi-Bo Wang, Yan Fu, Ya-Hui Ma, Qiong-Yao Li, Li-Yun Ma, Rui-Ping Cui, Yin-Chu Mi, Lan Tan, Jin-Tai Yu
Summary: Liver function may play a role in the progression of Alzheimer's disease. The study found that as AD progressed, certain liver function markers increased while others decreased. The relationship between liver function and CSF AD biomarkers indicates a potential mediation effect on cognition.
JOURNAL OF NEUROCHEMISTRY
(2024)