UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenografts

The whole-genome landscape of medulloblastoma subtypes

(2017) Paul A. Northcott et al.   NATURE

Preclinical Evaluation of UAB30 in Pediatric Renal and Hepatic Malignancies

(2016) A. M. Waters et al.   MOLECULAR CANCER THERAPEUTICS

Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

(2016) Lizhi Wu et al.   PLoS One

Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids

(2016) Barbara Bassani et al.   PLoS One

Preclinical Evaluation of a Novel RXR Agonist for the Treatment of Neuroblastoma

(2015) A. M. Waters et al.   MOLECULAR CANCER THERAPEUTICS

Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses

(2015) Gregory K. Friedman et al.   NEURO-ONCOLOGY

PBX1 Is a Favorable Prognostic Biomarker as It Modulates 13-cis Retinoic Acid-Mediated Differentiation in Neuroblastoma

(2014) N. Shah et al.   CLINICAL CANCER RESEARCH

Targeting Placental Growth Factor/Neuropilin 1 Pathway Inhibits Growth and Spread of Medulloblastoma

(2013) Matija Snuderl et al.   CELL

Changes in Gene Expression Profiling of Apoptotic Genes in Neuroblastoma Cell Lines upon Retinoic Acid Treatment

(2013) Jon Celay et al.   PLoS One

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

(2012) Marcel Kool et al.   ACTA NEUROPATHOLOGICA

PI3K/AKT and ERK regulate retinoic acid-induced neuroblastoma cellular differentiation

(2012) Jingbo Qiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Three Down and One To Go: Modeling Medulloblastoma Subgroups

(2012) Charles G. Eberhart   CANCER CELL

Tyrosine phosphatase inhibitors combined with retinoic acid can enhance differentiation of neuroblastoma cells and trigger ERK- and AKT-dependent, p53-independent senescence

(2012) Owen Clark et al.   CANCER LETTERS

TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid

(2012) Muhammad Imran et al.   EUROPEAN JOURNAL OF CANCER

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Oncolytic measles virus prolongs survival in a murine model of cerebral spinal fluid-disseminated medulloblastoma

(2012) A. W. Studebaker et al.   NEURO-ONCOLOGY

Molecular subgroups of medulloblastoma: the current consensus

(2011) Michael D. Taylor et al.   ACTA NEUROPATHOLOGICA

Assessment of oral toxicity and safety of 9-cis-UAB30, a potential chemopreventive agent, in rat and dog studies

(2011) Matthew Lindeblad et al.   DRUG AND CHEMICAL TOXICOLOGY

CRABP-II methylation: A critical determinant of retinoic acid resistance of medulloblastoma cells

(2011) Yuan-Shan Fu et al.   Molecular Oncology

Regulation of glioblastoma stem cells by retinoic acid: role for Notch pathway inhibition

(2011) M Ying et al.   ONCOGENE

A Pilot, First-in-Human, Pharmacokinetic Study of 9cUAB30 in Healthy Volunteers

(2010) J. M. Kolesar et al.   Cancer Prevention Research

Retinoids regulate stem cell differentiation

(2010) Lorraine J. Gudas et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

(2010) Yoon-Jae Cho et al.   JOURNAL OF CLINICAL ONCOLOGY

Medulloblastoma Comprises Four Distinct Molecular Variants

(2010) Paul A. Northcott et al.   JOURNAL OF CLINICAL ONCOLOGY

Evaluation of retinoic acid therapy for OTX2-positive medulloblastomas

(2010) Renyuan Bai et al.   NEURO-ONCOLOGY

Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study

(2009) Katherine K. Matthay et al.   JOURNAL OF CLINICAL ONCOLOGY

Chronic Disease in the Childhood Cancer Survivor Study Cohort: A Review of Published Findings

(2009) Lisa Diller et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion

(2009) Satish B Cheepala et al.   Molecular Cancer

Tumor Environment Dictates Medulloblastoma Cancer Stem Cell Expression and Invasive Phenotype

(2008) B. Annabi et al.   MOLECULAR CANCER RESEARCH

Combination of all-trans retinoic acid and paclitaxel-induced differentiation and apoptosis in human glioblastoma U87MG xenografts in nude mice

(2007) Surajit Karmakar et al.   CANCER