The combination of carmustine wafers and temozolomide for the treatment of malignant gliomas. A comprehensive review of the rationale and clinical experience

O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy w

(2012) Emmanuèle Lechapt-Zalcman et al.   CANCER

Impact of the per-operatory application of GLIADEL wafers (BCNU, carmustine) in combination with temozolomide and radiotherapy in patients with glioblastoma multiforme: Efficacy and toxicity

(2012) Petra Miglierini et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Results of phase I study of a multi-modality treatment for newly diagnosed glioblastoma multiforme using local implantation of concurrent BCNU wafers and permanent I-125 seeds followed by fractionated radiation and temozolomide chemotherapy

(2012) Christopher M. McPherson et al.   JOURNAL OF NEURO-ONCOLOGY

Temporal changes in magnetic resonance imaging characteristics of Gliadel wafers and of the adjacent brain parenchyma

(2012) S. Ulmer et al.   NEURO-ONCOLOGY

Cytoreductive surgery of glioblastoma as the key to successful adjuvant therapies: new arguments in an old discussion

(2011) Walter Stummer et al.   ACTA NEUROCHIRURGICA

Retrospective Comparison of Chemoradiotherapy Followed by Adjuvant Chemotherapy, With or Without Prior Gliadel Implantation (Carmustine) After Initial Surgery in Patients With Newly Diagnosed High-Grade Gliomas

(2011) Georges Noël et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Space-occupying cyst development in the resection cavity of malignant gliomas following Gliadel® implantation – incidence, therapeutic strategies, and outcome

(2011) Lutz Dörner et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Chemoresistance of glioblastoma cancer stem cells - much more complex than expected

(2011) Dagmar Beier et al.   Molecular Cancer

High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

(2010) R. Stupp et al.   ANNALS OF ONCOLOGY

Biodegradable Carmustine Wafers (Gliadel) Alone or in Combination with Chemoradiotherapy: The French Experience

(2010) Philippe Menei et al.   ANNALS OF SURGICAL ONCOLOGY

The paradoxical effect of bevacizumab in the therapy of malignant gliomas

(2010) E. M. Thompson et al.   NEUROLOGY

First-line treatment of malignant glioma with carmustine implants followed by concomitant radiochemotherapy: a multicenter experience

(2010) Hans Christoph Bock et al.   NEUROSURGICAL REVIEW

Risk Management in the Treatment of Malignant Gliomas with BCNU Wafer Implants

(2010) A. Giese et al.   Central European neurosurgery

Prognostic impact of O6-methylguanine-DNA methyltransferase silencing in patients with recurrent glioblastoma multiforme who undergo surgery and carmustine wafer implantation

(2009) Philippe Metellus et al.   CANCER

Overall survival of newly diagnosed glioblastoma patients receiving carmustine wafers followed by radiation and concurrent temozolomide plus rotational multiagent chemotherapy

(2009) Mary Lou Affronti et al.   CANCER

Phase II Trial of Gliadel plus O6-Benzylguanine in Adults with Recurrent Glioblastoma Multiforme

(2009) J. A. Quinn et al.   CLINICAL CANCER RESEARCH

The safety of temozolomide in the treatment of malignancies

(2009) Van Anh Trinh et al.   Expert Opinion On Drug Safety

Long-Term Survival of Patients With Glioblastoma Treated With Radiotherapy and Lomustine Plus Temozolomide

(2009) Martin Glas et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Trial of Temozolomide Plus O6-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma

(2009) Jennifer A. Quinn et al.   JOURNAL OF CLINICAL ONCOLOGY

Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial

(2009) Roger Stupp et al.   LANCET ONCOLOGY

Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma

(2008) J. N. Sarkaria et al.   CLINICAL CANCER RESEARCH

Safety profile of carmustine wafers in malignant glioma: a review of controlled trials and a decade of clinical experience

(2008) Michael Sabel et al.   CURRENT MEDICAL RESEARCH AND OPINION

A retrospective study of the safety of BCNU wafers with concurrent temozolomide and radiotherapy and adjuvant temozolomide for newly diagnosed glioblastoma patients

(2008) Edward Pan et al.   JOURNAL OF NEURO-ONCOLOGY

Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme

(2008) Matthew J. McGirt et al.   JOURNAL OF NEUROSURGERY

Abstracts for the Eighth Congress of the European Association for Neuro-Oncology (EANO)

(2008)   NEURO-ONCOLOGY

New (alternative) temozolomide regimens for the treatment of glioma

(2008) Wolfgang Wick et al.   NEURO-ONCOLOGY