Targeting αV-integrins decreased metastasis and increased survival in a nude rat breast cancer brain metastasis model

Cyclophosphamide Enhances Human Tumor Growth in Nude Rat Xenografted Tumor Models

(2015) Yingjen Jeffrey Wu et al.   NEOPLASIA

Targeting of αv-Integrins in Stem/Progenitor Cells and Supportive Microenvironment Impairs Bone Metastasis in Human Prostate Cancer

(2015) Geertje van der Horst et al.   NEOPLASIA

Defining the Role of Integrin αvβ6 in Cancer

(2012) A. Bandyopadhyay et al.   CURRENT DRUG TARGETS

Integrin αv Expression Is Required for the Acquisition of a Metastatic Stem/Progenitor Cell Phenotype in Human Prostate Cancer

(2011) Christel van den Hoogen et al.   AMERICAN JOURNAL OF PATHOLOGY

A randomised, phase II study of intetumumab, an anti-αv-integrin mAb, alone and with dacarbazine in stage IV melanoma

(2011) S O'Day et al.   BRITISH JOURNAL OF CANCER

Anti- v Integrin Monoclonal Antibody Intetumumab Enhances the Efficacy of Radiation Therapy and Reduces Metastasis of Human Cancer Xenografts in Nude Rats

(2010) S. Ning et al.   CANCER RESEARCH

Heterogeneous Blood-Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

(2010) P. R. Lockman et al.   CLINICAL CANCER RESEARCH

Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study

(2010) Tobias Bäuerle et al.   INTERNATIONAL JOURNAL OF CANCER

A phase 1, multicenter, open-label study of the safety of two dose levels of a human monoclonal antibody to human αv integrins, intetumumab, in combination with docetaxel and prednisone in patients with castrate-resistant metastatic prostate cancer

(2010) Franklin M. Chu et al.   INVESTIGATIONAL NEW DRUGS

Dynamic magnetic resonance imaging assessment of vascular targeting agent effects in rat intracerebral tumor models

(2010) L. L. Muldoon et al.   NEURO-ONCOLOGY

An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

(2009) Jay S Desgrosellier et al.   NATURE MEDICINE

Activation of tumor cell integrin  v 3 controls angiogenesis and metastatic growth in the brain

(2009) M. Lorger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

 v 6 Integrin Promotes the Invasion of Morphoeic Basal Cell Carcinoma through Stromal Modulation

(2008) D. Marsh et al.   CANCER RESEARCH

Inhibition of Metastatic Outgrowth from Single Dormant Tumor Cells by Targeting the Cytoskeleton

(2008) D. Barkan et al.   CANCER RESEARCH

Cilengitide: an integrin-targeting arginine–glycine–aspartic acid peptide with promising activity for glioblastoma multiforme

(2008) David A Reardon et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain

(2008) B. Gril et al.   JNCI-Journal of the National Cancer Institute