Brain to blood glutamate scavenging as a novel therapeutic modality: a review

Glutamate oxaloacetate transaminase: A new key in the dysregulation of glutamate in migraine patients

(2013) Francisco Campos et al.   CEPHALALGIA

The effects of estrogen and progesterone on blood glutamate levels during normal pregnancy in women

(2013) Svetlana Tsesis et al.   GYNECOLOGICAL ENDOCRINOLOGY

Amelioration of ischemic brain damage by peritoneal dialysis

(2013) María del Carmen Godino et al.   JOURNAL OF CLINICAL INVESTIGATION

The Effects of Peritoneal Dialysis on Blood Glutamate Levels

(2013) Boris Rogachev et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

The Role of Hypothermia in the Regulation of Blood Glutamate Levels in Naive Rats

(2013) Matthew Boyko et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Acute Mitochondrial Dysfunction after Blast Exposure: Potential Role of Mitochondrial Glutamate Oxaloacetate Transaminase

(2013) Peethambaran Arun et al.   JOURNAL OF NEUROTRAUMA

Brain energy metabolism in glutamate-receptor activation and excitotoxicity: Role for APC/C-Cdh1 in the balance glycolysis/pentose phosphate pathway

(2013) Patricia Rodriguez-Rodriguez et al.   NEUROCHEMISTRY INTERNATIONAL

Relationship between glutamate, GOT and GPT levels in maternal and fetal blood: A potential mechanism for fetal neuroprotection

(2012) Alexander Zlotnik et al.   EARLY HUMAN DEVELOPMENT

Blood Glutamate Scavenging: Insight into Neuroprotection

(2012) Akiva Leibowitz et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blood glutamate scavengers prolong the survival of rats and mice with brain-implanted gliomas

(2012) Angela Ruban et al.   INVESTIGATIONAL NEW DRUGS

Metabolic Pathways and Activity-Dependent Modulation of Glutamate Concentration in the Human Brain

(2012) Silvia Mangia et al.   NEUROCHEMICAL RESEARCH

Pharmacokinetics of Glutamate–Oxaloacetate Transaminase and Glutamate–Pyruvate Transaminase and Their Blood Glutamate-Lowering Activity in Naïve Rats

(2012) Matthew Boyko et al.   NEUROCHEMICAL RESEARCH

The Effect of Blood Glutamate Scavengers Oxaloacetate and Pyruvate on Neurological Outcome in a Rat Model of Subarachnoid Hemorrhage

(2012) Matthew Boyko et al.   Neurotherapeutics

Glutamate Excitoxicity Is the Key Molecular Mechanism Which Is Influenced by Body Temperature during the Acute Phase of Brain Stroke

(2012) Francisco Campos et al.   PLoS One

Insulin and glucagon share the same mechanism of neuroprotection in diabetic rats: role of glutamate

(2011) Rami Abu Fanne et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Effect of Glutamate and Blood Glutamate Scavengers Oxaloacetate and Pyruvate on Neurological Outcome and Pathohistology of the Hippocampus after Traumatic Brain Injury in Rats

(2011) Alexander Zlotnik et al.   ANESTHESIOLOGY

Blood levels of glutamate oxaloacetate transaminase are more strongly associated with good outcome in acute ischaemic stroke than glutamate pyruvate transaminase levels

(2011) Francisco Campos et al.   CLINICAL SCIENCE

Pyruvate’s blood glutamate scavenging activity contributes to the spectrum of its neuroprotective mechanisms in a rat model of stroke

(2011) Matthew Boyko et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Effect of estrogens on blood glutamate levels in relation to neurological outcome after TBI in male rats

(2011) Alexander Zlotnik et al.   INTENSIVE CARE MEDICINE

Oxaloacetate: A novel neuroprotective for acute ischemic stroke

(2011) Francisco Campos et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

GOT to rid the body of excess glutamate

(2011) Vivian I Teichberg   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

High blood glutamate oxaloacetate transaminase levels are associated with good functional outcome in acute ischemic stroke

(2011) Francisco Campos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotection by glutamate oxaloacetate transaminase in ischemic stroke: An experimental study

(2011) Francisco Campos et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Effects of Insulin, Glucagon, Glutamate, and Glucose Infusion on Blood Glutamate and Plasma Glucose Levels in Naive Rats

(2011) Alexander Zlotnik et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

β2 Adrenergic-mediated Reduction of Blood Glutamate Levels and Improved Neurological Outcome After Traumatic Brain Injury in Rats

(2011) Alexander Zlotnik et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

The Activation of β2-Adrenergic Receptors in Naïve Rats Causes a Reduction of Blood Glutamate Levels: Relevance to Stress and Neuroprotection

(2011) Alexander Zlotnik et al.   NEUROCHEMICAL RESEARCH

The Effect of Hyperthermia on Blood Glutamate Levels

(2010) Alexander Zlotnik et al.   ANESTHESIA AND ANALGESIA

The Effects of Estrogen and Progesterone on Blood Glutamate Levels: Evidence from Changes of Blood Glutamate Levels During the Menstrual Cycle in Women

(2010) Alexander Zlotnik et al.   BIOLOGY OF REPRODUCTION

Glutamate and astrocytes-Key players in human mesial temporal lobe epilepsy?

(2010) Tore Eid et al.   EPILEPSIA

Regulation of blood L-glutamate levels by stress as a possible brain defense mechanism

(2010) Alexander Zlotnik et al.   EXPERIMENTAL NEUROLOGY

Glutamate and the biology of gliomas

(2010) John de Groot et al.   GLIA

Neuroprotection by glucagon: role of gluconeogenesis

(2010) Rami Abu Fanne et al.   JOURNAL OF NEUROSURGERY

Determination of Factors Affecting Glutamate Concentrations in the Whole Blood of Healthy Human Volunteers

(2010) Alexander Zlotnik et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Neuroprotective effect of pyruvate and oxaloacetate during pilocarpine induced status epilepticus in rats

(2010) Andrezza Sossai Rodrigues Carvalho et al.   NEUROCHEMISTRY INTERNATIONAL

Glutamate receptors, neurotoxicity and neurodegeneration

(2010) Anthony Lau et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Oxaloacetate Decreases the Infarct Size and Attenuates the Reduction in Evoked Responses after Photothrombotic Focal Ischemia in the Rat Cortex

(2009) David Nagy et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

The Neuroprotective Effects of Oxaloacetate in Closed Head Injury in Rats is Mediated by its Blood Glutamate Scavenging Activity

(2009) Alexander Zlotnik et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Recurrent seizures and brain pathology after inhibition of glutamine synthetase in the hippocampus in rats

(2008) T. Eid et al.   BRAIN

Effective Prophylactic Treatments of Migraine Lower Plasma Glutamate Levels

(2008) A Ferrari et al.   CEPHALALGIA

Oxaloacetate restores the long-term potentiation impaired in rat hippocampus CA1 region by 2-vessel occlusion

(2008) Máté Marosi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

High plasma glutamate concentrations are associated with infarct growth in acute ischemic stroke

(2008) M. Castellanos et al.   NEUROLOGY

Homeostasis of glutamate in brain fluids: An accelerated brain-to-blood efflux of excess glutamate is produced by blood glutamate scavenging and offers protection from neuropathologies

(2008) V.I. Teichberg et al.   NEUROSCIENCE