期刊
JOURNAL OF NATURAL PRODUCTS
卷 73, 期 6, 页码 1038-1043出版社
AMER CHEMICAL SOC
DOI: 10.1021/np900750g
关键词
-
资金
- NIH [GM38130]
- NSF EAPSI [0714269]
- NSF OCE [0327070]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R29GM038130, R01GM038130, R55GM038130] Funding Source: NIH RePORTER
The marine bacterium Vibrio sp. DS40M4 has been found to produce a new triscatechol amide siderophore, trivanchrobactin (1), a related new biscatecholamide compound, divanchrobactin (2), and the previously reported siderophores vanchrobactin (3) and anguibactin (4). Vanchrobactin is comprised of L-serine, D-arginine, and 2,3-dihydroxybenzoic acid, while trivanchrobactin is a linear trimer of vanchrobactin joined by two serine ester linkages. The cyclic trivanchrobactin product was not detected. In addition to siderophore production, extracts of Vibrio sp. DS40M4 were screened for biologically active molecules; anguibactin was found to be cytotoxic against the P388 murine leukemia cell line (IC50 < 15 mu M).
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据