4.7 Article

Terpenoids from the Aerial Parts of Parasenecio deltophylla

期刊

JOURNAL OF NATURAL PRODUCTS
卷 73, 期 11, 页码 1954-1957

出版社

AMER CHEMICAL SOC
DOI: 10.1021/np1004505

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资金

  1. National Basic Research Program of China (973 ) [2007CB108903]
  2. National Science Foundation of China (NSFC) [J0630962/J0109]
  3. Ministry of Science and Technology of the People's Republic of China

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Five new modified eremophilane-type sesquiterpenes (1-5), including three norsesquiterpenes (1-3), and one new monoterpene (6) were isolated from the aerial parts of Parasenecio deltophylla. Their structures were established on the basis of HRMS and NMR methods. The cytotoxicity of compounds 1-4 and 6 against selected cancer cell lines, including human promyelocytic leukemia (HL-60) and human hepatoma (Hep-G2), was evaluated. Antioxidant activities of these compounds were assessed by ABTS and DPPH methods.

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