Article
Nutrition & Dietetics
Min Wu, Jianhang Cai, Zhengfeng Fang, Shanshan Li, Zhiqing Huang, Zizhong Tang, Qingying Luo, Hong Chen
Summary: In this study, polyphenols were extracted from Phyllanthus emblica L. fruit and their antioxidant and anti-aging abilities were determined. The polyphenols exhibited strong antioxidant capacities and anti-cholinesterase abilities, and showed a protective effect against the aging process in a Caenorhabditis elegans model.
Article
Agronomy
Po-Hsien Li, Chien-Wen Wang, Wen-Chien Lu, Tuzz-Ying Song, Chiun-C R. Wang
Summary: Phyllanthus emblica fruit extracts possess antioxidant, anti-inflammatory, and neuroprotective bioactivities. These extracts show strong antioxidant capacity, inhibit lipid peroxidation, and have anti-inflammatory effects. They also exhibit neuroprotective properties and could be used in health beverages, foods, and cosmetic products.
Article
Immunology
Xiang Nie, Huihui Li, Jin Wang, Yuanyuan Cai, Jiahui Fan, Beibei Dai, Chen Chen, Dao Wen Wang
Summary: The study revealed that the expression of lncRNAs is significantly dysregulated in acute myocarditis, potentially playing different roles in the progression of AM.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Chemistry, Applied
Cuifang Wang, Huaimeng Xu, Yixuan Wang
Summary: The study isolated six known compounds from the roots of Phyllanthus emblica, with secofriedelanophyllemblicine showing specific growth inhibition on MCF-7 breast cancer cells. Flow cytometric analysis indicated that secofriedelanophyllemblicine could induce G2 phase arrest in the cell-cycle progression of MCF-7 cells, suggesting its potential as a chemopreventive agent for breast cancer.
NATURAL PRODUCT RESEARCH
(2022)
Article
Food Science & Technology
Jin Gan, Xin Zhang, Chenjing Ma, Long Sun, Ying Feng, Zhao He, Hong Zhang
Summary: In this study, NKA-II resin was used to separate and purify the polyphenol extract from Phyllanthus emblica L. pomace. The purified extract showed significantly higher polyphenol content, improved antioxidant activity, and potential anti-Alzheimer's effects. These results suggest that the separated polyphenols from P. emblica pomace have valuable applications in research and development, and contribute to the utilization of P. emblica fruit.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Energy & Fuels
Vidhi Gupta, Dakuri Ramakanth, Chhavi Verma, Pradip K. Maji, Kirtiraj K. Gaikwad
Summary: This study successfully isolated cellulose nanocrystals from amla pomace, removing non-cellulosic components and obtaining CNC samples with high yield, crystallinity, and stability. The isolated CNCs exhibit excellent thermal stability and unique rod-like nanostructures, which may promote the sustainable conversion and circular utilization of food industry waste.
BIOMASS CONVERSION AND BIOREFINERY
(2021)
Review
Biochemistry & Molecular Biology
Maryam Gul, Zhi-Wei Liu, Iahtisham-Ul-Haq, Roshina Rabail, Fatima Faheem, Noman Walayat, Asad Nawaz, Muhammad Asim Shabbir, Paulo E. S. Munekata, Jose M. Lorenzo, Rana Muhammad Aadil
Summary: This review highlights the nutritional aspects and health-promoting effects of GOS, showing its potential for improving gut health, immune function, nutrient absorption, and protection against diseases.
Article
Chemistry, Organic
Xiao Han, Qi Wang, Xiangchao Luo, Xuli Tang, Zhe Wang, Di Zhang, Shugeng Cao, Pinglin Li, Guoqiang Li
Summary: Three novel sesquiterpenoids were isolated from marine soft corals and their structures were elucidated using various techniques. One of the compounds showed significant angiogenesis-promoting activity.
Article
Cardiac & Cardiovascular Systems
Vipul Sharma, Lisa S. Goessling, Anoop K. Brar, Chetanchandra S. Joshi, Indira U. Mysorekar, Pirooz Eghtesady
Summary: Prenatal infection with CVB3 can induce congenital heart defects in fetuses, with a dose-response relationship observed between viral titers and defect severity. Following exposure to CVB3, a significant decrease in cardiomyocyte proliferation was identified as the main cause for alterations in cardiac architecture and trabeculation.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Review
Pharmacology & Pharmacy
Arya Tjipta Prananda, Aminah Dalimunthe, Urip Harahap, Yogi Simanjuntak, Epina Peronika, Natasya Elsa Karosekali, Poppy Anjelisa Zaitun Hasibuan, Rony Abdi Syahputra, Putri Cahaya Situmorang, Fahrul Nurkolis
Summary: Phyllanthus emblica Linn, a member of the euphorbiaceae family, is widely distributed in tropical and subtropical nations. Its fruits are enriched with bioactive constituents that offer a diverse array of health-promoting attributes, including antioxidant and cardioprotective properties.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Green & Sustainable Science & Technology
Mijeong Choi
Summary: As human lifespan increases, there is a growing focus on external beauty management. However, this approach may have side effects or short-lived effects. It is therefore necessary to conduct research and development to maximize the effectiveness, eco-friendliness, and sustainability of beauty management. This study aimed to experimentally identify the anti-aging effects of extracts from Bahera, Phyllanthus emblica, Triphala, and Carica papaya, and to confirm their potential as whitening and wrinkle functional cosmetic materials. The results showed that these extracts had significant effects on whitening and wrinkle improvement, with even greater effects observed when ethanol was used as a co-solvent. This study has important practical implications for the beauty industry.
Article
Chemistry, Medicinal
Hai-feng Sun, Qiao Lv, Xiong Ji, Cheng Fang, Jia-xiang Fei, Xian-jun Liu, Jing-xun Liu, Xiao-hui Liu
Summary: The study aimed to investigate the potential bioactive compounds in Phyllanthus emblica L. fruit. Three new phenolic compounds and four known compounds were isolated and showed strong antioxidant abilities. The results contribute to the growing evidence of the health benefits of P. emblica and support its applications in functional foods and nutraceuticals.
NATURAL PRODUCT COMMUNICATIONS
(2023)
Article
Pharmacology & Pharmacy
Puyang Gong, Kehuan Yin, Xiaomin Luo, Jian Gu, Rui Tan, Yan Wu, Dapeng Li
Summary: This study aimed to elucidate the multitarget mechanisms of Phyllanthus emblica (PE) in treating liver fibrosis through proteomics analysis. The low-molecular-weight fraction of PE was found to have significant anti-liver fibrosis activity. Proteomics analysis identified potential targets, including COL1A2, ITGAV, TLR2, ACE, and PDGFRB, for PE treatment of liver fibrosis.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Food Science & Technology
Min Wu, Ming Liu, Feiyang Wang, Jianhang Cai, Qingying Luo, Shanshan Li, Junxiang Zhu, Zizhong Tang, Zhengfeng Fang, Caixia Wang, Hong Chen
Summary: The present study investigated the inhibition mechanism of polyphenols from Phyllanthus emblica Linn. fruit (PEF) on acetylcholinesterase (AChE). The most active components in PEF, including myricetin, quercetin, fisetin, and gallic acid, showed strong inhibition ability on AChE. Kinetic studies revealed different inhibition modes for different polyphenols. The active PEF polyphenols inhibited AChE by quenching its intrinsic fluorescence and inducing changes in its secondary structure.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Immunology
Qingru Yang, Yuhan Li, Yan Wang, Xiaorong Qiao, Tingjun Liu, Hua Wang, Hongxing Shen
Summary: This study found that circSIAE can target TAOK2 through sponge adsorption of miR-331-3p to inhibit the replication and proliferation of CVB3 virus.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
