期刊
JOURNAL OF NATURAL PRODUCTS
卷 72, 期 11, 页码 2043-2045出版社
AMER CHEMICAL SOC
DOI: 10.1021/np900288x
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资金
- NIH P41 [GM68944, R01GM0758556]
Scytoscalarol (1), a antimicrobial sesterterpene bearing a guanidino group, was isolated from the cultured cyanobacterium Scytonema sp. (UTEX 1163) by bioassay-guided fractionation. The chemical structure was determined by spectroscopic analysis including MS and 1D and 2D NMR. Scytoscalarol (1) showed antimicrobial activities against Bacillus anthracis, Staphylococcus aureus, Escherichia coli, Candida albicans, and Mycobacterium tuberculosis with MIC values in the range from 2 to 110 mu M.
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