期刊
JOURNAL OF NATURAL PRODUCTS
卷 71, 期 9, 页码 1591-1594出版社
AMER CHEMICAL SOC
DOI: 10.1021/np800435c
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资金
- the University of Malaya
- MOSTI, Malaysia (ScienceFund)
Seven new indole alkaloids of the Aspidosperma type, jerantinines A-G (1-7), were isolated from a leaf extract of the Malayan Tabernaemontana corymbosa. The structures were established using NMR and MS analysis. Five of the alkaloids isolated and two derivatives (1-5, 8, 9) displayed pronounced in vitro cytotoxicity against human KB cells (IC(50) < 1 mu g/mL).
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