期刊
JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
卷 14, 期 10, 页码 7363-7373出版社
AMER SCIENTIFIC PUBLISHERS
DOI: 10.1166/jnn.2014.9579
关键词
Nanogels; Molecular Delivery; Biocompatibility; Self-Assembly; Metal Nanoparticles
类别
资金
- Mid-career Researcher Program through the National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology (MEST) [2011-0028796]
- National Research Foundation of Korea [2011-0028796] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
Recently, nanogels have been extensively studied as a means to deliver bioactive molecules such as drugs, proteins, and vaccines due to their versatile and unique properties such as high water absorption, easy production, surface modification, high stability and biocompatibility. Various materials including natural polymers, synthetic polymers, peptides, and proteins have been selected for fabrication of nanogels to achieve a targeted, sustained, or protected delivery depending on biomedical applications and bioactive molecules. This review describes a variety of nanogel fabrication for applications in molecular delivery systems. The detail of materials and approaches for preparation of nanogels will be discussed, including free radical polymerization, controlled/living radical polymerization, self-assembly, and metal/nanogel composites.
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