Polymyxin Combinations: Pharmacokinetics and Pharmacodynamics for Rationale Use

Evaluation of Double- and Triple-Antibiotic Combinations for VIM- and NDM-Producing Klebsiella pneumoniae byIn VitroTime-Kill Experiments

(2014) T. Tängdén et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparison of colistin–carbapenem, colistin–sulbactam, and colistin plus other antibacterial agents for the treatment of extremely drug-resistant Acinetobacter baumannii bloodstream infections

(2014) A. Batirel et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Activity of colistin combined with doripenem at clinically relevant concentrations against multidrug-resistant Pseudomonas aeruginosa in an in vitro dynamic biofilm model

(2014) J. Lora-Tamayo et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Risk Factors for Treatment Failure of Polymyxin B Monotherapy for Carbapenem-Resistant Klebsiella pneumoniae Infections

(2013) Yanina Dubrovskaya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Successful Ertapenem-Doripenem Combination Treatment of Bacteremic Ventilator-Associated Pneumonia Due to Colistin-Resistant KPC-Producing Klebsiella pneumoniae

(2013) Giancarlo Ceccarelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic Activity of Colistin and Rifampin Combination against Multidrug-Resistant Acinetobacter baumannii in anIn VitroPharmacokinetic/Pharmacodynamic Model

(2013) Hee Ji Lee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutations of theompK36Porin Gene and Promoter Impact Responses of Sequence Type 258, KPC-2-Producing Klebsiella pneumoniae Strains to Doripenem and Doripenem-Colistin

(2013) Cornelius J. Clancy et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Experience of Colistin-Glycopeptide Combination in Critically Ill Patients Infected with Gram-Negative Bacteria

(2013) Nicola Petrosillo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Efficacy and Safety of the Combination of Colistin plus Vancomycin for the Treatment of Severe Infections Caused by Carbapenem-Resistant Acinetobacter baumannii

(2013) José Garnacho-Montero et al.   CHEMOTHERAPY

Colistin and Rifampicin Compared With Colistin Alone for the Treatment of Serious Infections Due to Extensively Drug-Resistant Acinetobacter baumannii: A Multicenter, Randomized Clinical Trial

(2013) Emanuele Durante-Mangoni et al.   CLINICAL INFECTIOUS DISEASES

Population Pharmacokinetics of Intravenous Polymyxin B in Critically Ill Patients: Implications for Selection of Dosage Regimens

(2013) Ana M. Sandri et al.   CLINICAL INFECTIOUS DISEASES

Successful treatment of post-neurosurgical multidrug-resistant Pseudomonas aeruginosa meningo-encephalitis with combination therapy of colistin, rifampicin and doripenem

(2013) P. Morelli et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Treatment Outcome of Bacteremia Due to KPC-Producing Klebsiella pneumoniae: Superiority of Combination Antimicrobial Regimens

(2012) Zubair A. Qureshi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Combination of Colistin and Doripenem Is Synergistic against Klebsiella pneumoniae at Multiple Inocula and Suppresses Colistin Resistance in anIn VitroPharmacokinetic/Pharmacodynamic Model

(2012) Zakuan Z. Deris et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Predictors of Mortality in Bloodstream Infections Caused by Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Importance of Combination Therapy

(2012) M. Tumbarello et al.   CLINICAL INFECTIOUS DISEASES

High-Dose, Extended-Interval Colistin Administration in Critically Ill Patients: Is This the Right Dosing Strategy? A Preliminary Study

(2012) L. Dalfino et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetics and pharmacodynamics of ‘old’ polymyxins: what is new?

(2012) Phillip J. Bergen et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Colistin vs. the combination of colistin and rifampicin for the treatment of carbapenem-resistant Acinetobacter baumannii ventilator-associated pneumonia

(2012) H. AYDEMIR et al.   EPIDEMIOLOGY AND INFECTION

Epidemiology, Clinical Characteristics and Outcomes of Extensively Drug-Resistant Acinetobacter baumannii Infections among Solid Organ Transplant Recipients

(2012) Ryan K. Shields et al.   PLoS One

Clinically Relevant Plasma Concentrations of Colistin in Combination with Imipenem Enhance Pharmacodynamic Activity against Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula

(2011) Phillip J. Bergen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic Killing of Multidrug-Resistant Pseudomonas aeruginosa at Multiple Inocula by Colistin Combined with Doripenem in an In Vitro Pharmacokinetic/Pharmacodynamic Model

(2011) Phillip J. Bergen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetics of Colistin Methanesulfonate and Formed Colistin in Critically Ill Patients from a Multicenter Study Provide Dosing Suggestions for Various Categories of Patients

(2011) S. M. Garonzik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Predictors of mortality in patients with bloodstream infections caused by KPC-producing Klebsiella pneumoniae and impact of appropriate antimicrobial treatment

(2011) O. Zarkotou et al.   CLINICAL MICROBIOLOGY AND INFECTION

High mortality rates among solid organ transplant recipients infected with extensively drug-resistant Acinetobacter baumannii: using in vitro antibiotic combination testing to identify the combination of a carbapenem and colistin as an effective treatment regimen

(2011) Ryan K. Shields et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Activity of tigecycline alone and in combination with colistin and meropenem against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains by time–kill assay

(2011) Spyros Pournaras et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

In vitro activity of teicoplanin combined with colistin versus multidrug-resistant strains of Acinetobacter baumannii

(2011) D. W. Wareham et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In Vitro Double and Triple Bactericidal Activities of Doripenem, Polymyxin B, and Rifampin against Multidrug-Resistant Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli

(2010) C. Urban et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potent Synergy and Sustained Bactericidal Activity of a Vancomycin-Colistin Combination versus Multidrug-Resistant Strains of Acinetobacter baumannii

(2010) N. C. Gordon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Activity of doripenem with and without levofloxacin, amikacin, and colistin against Pseudomonas aeruginosa and Acinetobacter baumannii

(2010) Glenn A. Pankuch et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Infections by pandrug-resistant gram-negative bacteria: clinical profile, therapeutic management, and outcome in a series of 21 patients

(2010) C. Tsioutis et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

The impact of polymyxin B dosage on in-hospital mortality of patients treated with this antibiotic

(2010) L. S. Elias et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Does the Activity of the Combination of Imipenem and Colistin In Vitro Exceed the Problem of Resistance in Metallo- -Lactamase-Producing Klebsiella pneumoniae Isolates?

(2009) M. Souli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Population Pharmacokinetic Analysis of Colistin Methanesulfonate and Colistin after Intravenous Administration in Critically Ill Patients with Infections Caused by Gram-Negative Bacteria

(2009) D. Plachouras et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Colistin therapy for microbiologically documented multidrug-resistant Gram-negative bacterial infections: a retrospective cohort study of 258 patients

(2009) Matthew E. Falagas et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Looming Global-Scale Failures and Missing Institutions

(2009) B. Walker et al.   SCIENCE

Colistin serum concentrations after intravenous administration in critically ill patients with serious multidrug-resistant, gram-negative bacilli infections: A prospective, open-label, uncontrolled study

(2008) Nikolaos Markou et al.   CLINICAL THERAPEUTICS

Pandrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii infections: Characteristics and outcome in a series of 28 patients

(2008) Matthew E. Falagas et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Comparison of once-, twice- and thrice-daily dosing of colistin on antibacterial effect and emergence of resistance: studies with Pseudomonas aeruginosa in an in vitro pharmacodynamic model

(2008) P. J. Bergen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Intravenous colistin sulphomethate sodium for therapy of infections due to multidrug-resistant gram-negative bacteria

(2008) Vicente Pintado et al.   JOURNAL OF INFECTION