Preparation of Photocontrollable, Nontoxicity Complex of Phenylazophenylalanine Modified CdS Quantum Dots with Cyclodextrin

A novel complex of beta-cyclodextrin with phenylazophenylalanine (PAP)-conjugated CdS quantum dot (Fazo-CdS QD) was fabricated for a photocontrollable toxicity study of CdS. Photocontrolling release of Fazo-CdS QDs from the complex was confirmed under UV irradiation by the steady state photoluminescence (PL) spectroscopy. The cytotoxicity of the surface modified CdS QDs was evaluated in vivo. The results suggest that the Fazo-CdS QDs conjugated with beta-CD could be almost nontoxicity, which may have great potential applications in biological labeling and imaging.