Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)

标题
Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2)
作者
关键词
Ceritinib, ALK inhibitor, ABCB1, ABCG2, Blood-brain barrier, Oral availability
出版物
PHARMACOLOGICAL RESEARCH
Volume 102, Issue -, Pages 200-207
出版商
Elsevier BV
发表日期
2015-09-09
DOI
10.1016/j.phrs.2015.09.003

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