Article
Chemistry, Multidisciplinary
Daekyung Kang, Changhee Son, Hakseon Lee, Hongsik Park, Taewan Kim, Jonghoo Park
Summary: Gold nanoparticles are widely used in nanomaterial-based sensors and biomedical technologies due to their chemical inertness and excellent physiochemical properties. The surface functionalization of gold nanoparticles with ligands, such as tiopronin, can enhance biocompatibility and interaction with biomolecules. A novel aqueous synthesis method without the need for a dialysis process has been developed for precise size control of tiopronin-capped gold nanoclusters/nanoparticles.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Multidisciplinary
Ya-Ge Wu, Jia-Hong Huang, Chong Zhang, Xiang-Kun Guo, Wei-Na Wu, Xi-Yan Dong, Shuang-Quan Zang
Summary: A novel Ag-36 nanocluster with a closed electronic structure and eight valence electrons is described, which shares a similar structure with an open-shell Ag-34 nanocluster with three valence electrons, except for the replacement of two S(2-) anions with two (Ag-PPh3)(+) cations in the shell. The precise structural modulation results in varying levels of singlet oxygen photogeneration activity due to the distinct optical gaps of the nanoclusters.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Yueqiu Lin, Shanghai Yong, Cole R. Scholtz, Cui Du, Shasha Sun, Jay D. Steinkruger, Xin Zhou, Chen Zhou, Shengyang Yang
Summary: This study investigated the influence of surface chemistry on the biodistribution and pharmacokinetics of dual-ligand luminescent gold nanoparticles (AuNPs) in vivo. We synthesized and characterized four types of dual-ligand AuNPs and found that variation of one of the surface ligands had a significant impact on the pharmacokinetics and biodistribution, including lung, digestive organs, and blood circulation time.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2023)
Article
Chemistry, Multidisciplinary
Li Tang, Zhengmao Yin, Ru Wang, Bin Wang, Kefan Jiang, Mei Ding, Shuxin Wang
Summary: In this study, two compounds Cd12Ag32-1 and Cd12Ag32-2 were synthesized and structurally determined by single-crystal X-ray diffraction. The selective adsorption of phosphine ligands caused by different types of thiol ligands was found. Additionally, Cd12Ag32-1 exhibited a unique stacking pattern in a superlattice with multiple inter-cluster channels. This study contributes to a deeper understanding of the effect of mixed ligands on nanocluster formation and the correlation between structure and properties.
Article
Chemistry, Multidisciplinary
Asier R. R. Muguruza, Alessandro di Maio, Nikolas J. J. Hodges, Jessica M. A. Blair, Zoe Pikramenou
Summary: In this study, a novel hybrid silica nanoparticle system was designed, which carried membrane targeting groups and encapsulated antibiotics along with a ruthenium luminescent tracking agent for optical detection of nanoparticle delivery in bacterial cells. The hybrid system successfully delivered vancomycin and exhibited efficacy against various Gram-negative bacterial species. The penetration of nanoparticles in bacterial cells was confirmed via the luminescence of the ruthenium signal. These findings demonstrate that nanoparticles modified with aminopolycarboxylate chelating groups can serve as an effective delivery system for inhibiting bacterial growth in species where molecular antibiotics are ineffective. This design provides a new platform for delivering antibiotics that cannot penetrate the bacterial membrane alone.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Inorganic & Nuclear
Vonika Ka -Man Au
Summary: The advancement of organometallic chemistry has accelerated the development of functional materials based on metal complexes. Organometallic complexes based on the gold(III) system have gained increasing attention. Bidentate cyclometalating ligands are commonly used for the synthesis of gold(III) complexes with tunable photophysical properties, and they have applications in organic light-emitting diodes and biology.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Rashid Ilmi, Xiaofang Li, Nawal K. Al Rasbi, Liang Zhou, Wai-Yeung Wong, Paul R. Raithby, Muhammad S. Khan
Summary: Two new organo-europium complexes were synthesized and characterized, and they were used to fabricate red organic light emitting diodes. Exceptional device performance was achieved through device engineering optimization.
DALTON TRANSACTIONS
(2023)
Article
Optics
Zhen Hu, Xiongjian Huang, Zhengwen Yang, Jianbei Qiu, Zhiguo Song, Junying Zhang, Guoping Dong
Summary: This study demonstrates that rare earth ions doped transparent glass can be used as a medium for 3D optical information storage and data encryption, with reversible color change and luminescence modulation. Information data can be repeatedly written and erased in arbitrary 3D space of transparent glass, showing excellent reproducibility and storage capacity.
LIGHT-SCIENCE & APPLICATIONS
(2021)
Article
Chemistry, Inorganic & Nuclear
Rashid Ilmi, Xiaofang Li, Nawal K. Al Rasbi, Liang Zhou, Wai-Yeung Wong, Paul R. Raithby, Muhammad S. Khan
Summary: Two new organo-europium complexes have been successfully synthesized and characterized. These complexes exhibit strong red emissions in the solid state with high photoluminescence quantum yields. They were used as dopants in the emitting layer of red organic light emitting diodes, resulting in exceptional overall performance through device engineering.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Physical
Guocheng Deng, Kangjae Lee, Hongwen Deng, Megalamane S. Bootharaju, Nanfeng Zheng, Taeghwan Hyeon
Summary: This study reports the synthesis and structure of a bimetallic AgCu cluster, Ag12Cu4, which exhibits crystallization-induced and aggregation-induced emission enhancement phenomena. The detailed structural analysis reveals the presence of abundant intercluster interactions, leading to strong photoluminescence enhancement in the solid state.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Review
Chemistry, Analytical
Vaibhavkumar N. Mehta, Nirav Ghinaiya, Jigneshkumar Rohit, Rakesh Kumar Singhal, Hirakendu Basu, Suresh Kumar Kailasa
Summary: Metal nanoparticles have shown significant potential in enhancing the sensitivity of UV -Visible spectrometry and can be used for miniaturized colorimetric assay of various molecules. The interaction between metal nanoparticles and trace level pesticides can induce aggregation and cause noticeable color changes. This review summarizes the role of ligand chemistry on metal nanoparticles for colorimetric detection of pesticides and discusses the challenges and future perspectives.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
David Ventura-Espinosa, Santiago Martin, Hermenegildo Garcia, Jose A. Mata
Summary: The ligand has a significant impact on the stability of gold nanoparticles on graphene, with NHC ligands containing pyrenyl handle showing superior catalytic activity and ability to be recycled at least ten times while maintaining particle size, demonstrating high stability.
JOURNAL OF CATALYSIS
(2021)
Article
Chemistry, Multidisciplinary
Wenyan Nie, Kui He, Zhipeng Zhao, Xiaoxi Luo, Jinbin Liu
Summary: We developed a facile in situ strategy to precisely control DNA aptamer valences on the surface of luminescent gold nanoparticles (AuNPs) with emission in the second near-infrared window. We further demonstrated that not only the tumor-targeting efficiencies but also the subcellular transport of AuNPs show precise valence dependence.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Dominick D. Ortega, Nicholas Pavlakovich, Young-Seok Shon
Summary: This study investigates the structure-property relationships of lipid-nanoparticle assemblies (LNAs) and their catalytic activity in hydrogenation reactions. It is found that LNAs with palladium nanoparticles show decreased colloidal stability but increased catalytic activity. Temperature plays a significant role in the conversion yield of substrates in LNAs, with higher temperatures leading to higher conversion rates.
Article
Chemistry, Multidisciplinary
Ying Zhang, Sheng-Rong He, Ying Yang, Tai-Song Zhang, Ze-Min Zhu, Wenwen Fei, Man-Bo Li
Summary: An amidation strategy has been developed for the precision functionalization of Au-11 nanoclusters based on preorganized nitrogen sites, which does not change the number of gold atoms in the kernel but slightly modifies their arrangement with the introduction of functionality and chirality.This method represents a relatively mild approach for the modification of metal nanoclusters and improves their stability and oxidation barrier.The method developed here has the potential to be a generalizable strategy for the precision functionalization of metal nanoclusters.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Multidisciplinary
Tianxiang Chen, Bolong Huang, Sarah Day, Chiu Chung Tang, Shik Chi Edman Tsang, Kwok-yin Wong, Tsz Woon Benedict Lo
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Electrochemistry
Chui-Shan Tsang, Lawrence Yoon Suk Lee, Kwong-Chak Cheung, Pak-Ho Chan, Wing-Leung Wong, Kwok-Yin Wong
Summary: The study reveals that ligands with longer alkyl chains can effectively promote the conversion of Ru-III-OH to Ru-IV=O, and the presence of perchlorate anions can further enhance this conversion. Additionally, the alkyl chain on the ligands also helps promote the adsorption of ruthenium complexes on the electrode surface.
Article
Chemistry, Physical
Qi Xue, Ka Hin Chan, Cheuk Ki Yim, Bryan Kit Yue Ng, Tianxiang Chen, Sarah J. Day, Chiu Tang, Shogo Kawaguchi, Kwok-Yin Wong, Tsz Woon Benedict Lo
Summary: The guest-anion-induced photoluminescence enhancement of metalorganic frameworks was found to be significant only with carbonate and fluoride ions. These ions interact with framework amino functional groups through hydrogen bonds, forming a molecular bridge and perturbing electronic densities.
CHEMISTRY OF MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Pei-Gang Chen, Zhiyong Li, Yun Qi, Tsz Wing Lo, Shubo Wang, Wei Jin, Kwok-Yin Wong, Shanhui Fan, Anatoly Zayats, Dangyuan Lei
Summary: The research demonstrates a valleytronic system based on high-quantum-yield trion emission in monolayer WS2, chirally coupled to a low-loss microfiber, achieving long-range directional routing of valley excitations and selective address of valley-dependent emission from different spatial locations. This valleytronic interface can be integrated with fiber communication devices, providing a new mechanism for optical information transport and manipulation in classical and quantum regimes.
Article
Chemistry, Multidisciplinary
Qi Xue, Bryan Kit Yue Ng, Ho Wing Man, Tai-Sing Wu, Yun-Liang Soo, Molly Mengjung Li, Shogo Kawaguchi, Kwok Yin Wong, Shik Chi Edman Tsang, Bolong Huang, Tsz Woon Benedict Lo
Summary: Research focusing on precisely tuning the nuclearity of supported metal nanoclusters, particularly on the Zr-based metal-organic framework UiO-66-NH2, offers insights into the interplay between surface structures, adsorption configurations, and catalytic reactivities of Cu-oxo nanoclusters, providing critical information for the engineering of more superior catalytic systems.
Article
Nanoscience & Nanotechnology
Huaping Jia, Zhiyong Li, Bingzhe Wang, Guichuan Xing, Yat Lam Wong, Hui Ren, Mingjie Li, Kwok-Yin Wong, Dangyuan Lei, Lok-Wing Wong, Jiong Zhao, Wendong Zhang, Shengbo Sang, Aoqun Jian, Xuming Zhang
Summary: Metallic nanohole arrays that excite both surface plasmon polariton (SPP) and localized surface plasmon resonance (LSPR) in a single thin film have attracted great interest in the field of plasmonics. In this study, a novel design of photoelectrodes for solar photocatalysis applications was proposed by burying an Au nanohole array (AuNHA) under a thin TiO2 layer and decorating Pt nanoparticles randomly on the surface. The Pt/TiO2/AuNHA nanocomposite showed significant enhancements in photocurrent density, incident photon-to-current conversion efficiency, and degradation of methyl orange compared to the Pt/TiO2/Au film.
Article
Biochemistry & Molecular Biology
Wai-Po Kong, Furong Gong, Pui-Kin So, Yu Wai Chen, Pak-Ho Chan, Yun-Chung Leung, Kwok-Yin Wong
Summary: In this study, the authors used hydrogen-deuterium exchange mass spectrometry to investigate the structural dynamic changes and binding interfaces within the FtsQBL protein complex in Escherichia coli. Their findings revealed the interactions between FtsB and FtsL at both the periplasmic and transmembrane regions, as well as the interaction between FtsB and FtsQ at its C-terminal region. The study provides valuable insights into the roles of FtsQBL complexation in regulating divisome activity.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Biophysics
Ying Wang, Ruolan Du, Lawrence Yoon Suk Lee, Kwok-Yin Wong
Summary: Nanozymes, heterogeneous nanomaterials with enzyme-like characteristics, offer significant advantages as alternatives to natural enzymes. Single-atom nanozymes (SAzymes), composed of single-atomic active sites, have remarkable enzyme-like activity and specificity. This review provides an overview of SAzymes, including their discoveries, advantages, and classifications, as well as discussions on reaction mechanisms, design principles, and biosensing applications. The challenges and future perspectives of SAzymes as the next-generation nanozymes are also discussed.
BIOSENSORS & BIOELECTRONICS
(2022)
Review
Materials Science, Multidisciplinary
Xing Liu, Yanli Du, Stefanos Mourdikoudis, Guangchao Zheng, Kwok-Yin Wong
Summary: This review summarizes recent research works on the synthesis, properties, and applications of chiral magnetic oxide nanomaterials (CMONs), which combine the beneficial effects of chirality and magnetism in a single unit. The simultaneous presence of magnetic properties, catalytic activity, biocompatibility and optical activity, or magneto-optical effects, makes CMONs widely applicable in biomedical, optical, and electronic devices as well as in catalysis and sensing.
ADVANCED OPTICAL MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Ying Wang, Yong Wang, Lawrence Yoon Suk Lee, Kwok-Yin Wong
Summary: This mini-review outlines the research progress and characterization techniques of dual-atomic-site catalysts (DACs) and presents representative examples of DAC-based nanozymes. It also provides current challenges and perspectives for researchers interested in this field.
Article
Biochemistry & Molecular Biology
Ruo-Lan Du, Ning Sun, Yik-Hong Fung, Yuan-Yuan Zheng, Yu-Wei Chen, Pak-Ho Chan, Wing-Leung Wong, Kwok-Yin Wong
Summary: In this study, potential inhibitors of FtsZ were identified through virtual screening and bioassays, with one candidate, Dacomitinib (S2727), showing potent inhibitory activity against MRSA strains for the first time. The binding mode of Dacomitinib in FtsZ was analyzed by docking, revealing Asp(199) and Thr(265) as essential residues involved in the interactions.
RSC MEDICINAL CHEMISTRY
(2022)
Review
Chemistry, Multidisciplinary
Weiran Zheng, Lawrence Yoon Suk Lee, Kwok-Yin Wong
Summary: Direct seawater electrolysis offers a new opportunity to reduce the cost of hydrogen production, but challenges in long-term performance stability must be addressed. Common causes of performance decline during seawater electrolysis are discussed, along with ongoing efforts in counter-measurements such as electrocatalyst optimization and cell design. The need for a consensus on evaluating the stability of seawater electrolysis is emphasized.
Article
Chemistry, Multidisciplinary
Yong Wang, Zhiguang Liang, Yuanyuan Zheng, Alan Siu-Lun Leung, Siu-Cheong Yan, Pui-Kin So, Yun-Chung Leung, Wing-Leung Wong, Kwok-Yin Wong
Summary: A series of isatin derivatives with different substituent groups were systematically designed and synthesized to study their inhibition of bacterial enzyme activity and antimicrobial potency. Modifying the substituent positions can maximize the antimicrobial potency and inhibitory action against the bacterial enzyme, leading to better understanding of the structure-activity relationship.
Article
Food Science & Technology
Ping Zeng, Lanhua Yi, Melody Wong, Sheng Chen, Kin-Fai Chan, Kwok-Yin Wong
Summary: Research has shown that zp16 can inhibit the growth of Pectobacterium carotovorum by affecting membrane potential and permeability, as well as triggering reactive oxygen accumulation. Furthermore, zp16 also kills the bacteria by affecting the expression of key proteins related to arginine and peptidoglycan biosynthesis.
ACS FOOD SCIENCE & TECHNOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Guangchao Zheng, Jijun He, Vished Kumar, Shenli Wang, Isabel Pastoriza-Santos, Jorge Perez-Juste, Luis M. Liz-Marzan, Kwok-Yin Wong
Summary: Chiral objects lack mirror planes and inversion symmetry, exhibiting the same physical properties as their mirror images except for often opposite chiroptical activity. Recent studies have shown interesting implications of chirality on the optical properties of metal nanoparticles, specifically related to localized surface plasmon resonance phenomena.
CHEMICAL SOCIETY REVIEWS
(2021)
