Article
Fisheries
Mai Dang, Tran Duc Dien, Ut Phan Van, Vo Thi Ha, Vu Viet Dung, Nguyen Trinh Duc Hieu, Viet Cuong Hua, Nguyen Thi Kim Hue, Nguyen Thi Thu Giang, Vu Huu Truong, Ha Thanh Dong
Summary: Barramundi, an economically important species in the Asia-Pacific region, has been threatened by various infectious diseases including the newly emerging Lates calcarifer herpes virus (LCHV). This study investigated the histology of LCHV outbreaks and identified a pathognomonic feature, the presence of intra-nuclear inclusion bodies (IIBs), in infected fish. Experimental infection confirmed the presence of IIBs in multiple organs, providing a valuable tool for the histological diagnosis and surveillance of this viral disease in barramundi farming countries.
Article
Fisheries
Alexander O. Kasumyan, Olga M. Isaeva, Le T. K. Oanh
Summary: Fish meal is a limiting factor for fish feed development. The use of forage fish as a protein source in fish feed is unsustainable and hinders the aquaculture industry. Researchers have explored alternative protein sources, such as food industry by-products and local raw materials. This study found that most echinoderm species are unpalatable for barramundi fish and should not be recommended as an ingredient in barramundi feed.
Article
Fisheries
Celestine Terence, Jose A. Domingos, Joseph Angelo Uichanco, Yann Monteil, Loic Monteil, Emmanuel De Braux, Quyen Q. T. Banh, Susan Gibson-Kueh, Dean R. Jerry
Summary: The study in Singapore found that barramundi farmed in sea cages are undergoing precocious sex change, with a decrease in male individuals and an increase in females as early as 2-3 years old. This phenomenon challenges hatcheries in selecting and maintaining male fish for breeding purposes, and further investigation is needed to understand the causes of this early sex change.
AQUACULTURE REPORTS
(2021)
Article
Fisheries
Kensuke Ichida, Reoto Tani, Somkiat Sreebun, Araya Jangprai, Pailin Pasomboon, Ryosuke Yazawa, Goro Yoshizaki, Surintorn Boonanuntanasarn
Summary: Selective breeding is crucial for sustainable aquaculture, and barramundi is no exception. Developing a germ cell transplantation method is essential for preserving diverse genetic characteristics. Transplanting frozen germ cells into recipients is a powerful tool for obtaining the next generation.
Article
Fisheries
Adrien F. Marc, Jarrod L. Guppy, Paige Bauer, Peter Mulvey, Dean R. Jerry, Damien B. B. P. Paris
Summary: This study optimized advanced tools to evaluate the sperm function of barramundi, a tropical finfish species popular in aquaculture. The findings provide insights for future research on male fertility and reproductive constraints in captive-bred broodstock, highlighting the importance of assessing sperm quality for commercial spawns.
Article
Fisheries
Richard Le Boucher, Weiqiang Chung, Jessalin Ng Kai Lin, Lydia Shun En Tan, Zhi Weng Josiah Poon, Co Sin Lee
Summary: Efficient aquaculture management requires optimizing feed intake to balance fish productivity and environmental waste. Automated feeders with daily feed intake (DFI) prediction capabilities are popular for achieving this balance. This study optimized DFI prediction using various learning algorithms and nonlinear functional forms, showing that feed selection, fish characteristics, and environmental factors significantly impact DFI. Nonlinear models demonstrated higher accuracy, and the use of adaptive algorithms facilitated the development of effective DFI prediction models.
Article
Engineering, Marine
Alexander Kasumyan, Olga Isaeva, Le T. K. Oanh
Summary: This study examined the taste attractiveness of 21 amino acids and 4 taste substances for barramundi, and investigated their feeding behavior. The results showed that citric acid, cysteine, and alanine were palatable, while sucrose and 7 amino acids had an aversive taste. Barramundi often made repeated grasps and rejections of pellets, leading to the destruction of the pellets.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Environmental Sciences
Zhengyi Fu, Shengjie Zhou, Gang Yu, Rui Yang, Mingyang Han, Zhenhua Ma
Summary: High lipid diet can enhance hepatic lipid metabolism and growth performance of barramundi, but may lead to increase in useless adipose tissue; High carbohydrate diet may result in hepatic glycogen accumulation, without significant improvement in growth performance or metabolic abnormalities.
FRONTIERS IN MARINE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Brien H. Roberts, John R. Morrongiello, David L. Morgan, Alison J. King, Thor M. Saunders, David A. Crook
Summary: The relationship between individual growth rate and the timing of sex change plays a significant role in reproductive output and population productivity. Fast growth is associated with a younger age at sex change, but not necessarily a smaller size at sex change. Individuals that grow faster, particularly as large females, contribute more to population fecundity and ultimately obtain higher fitness.
SCIENTIFIC REPORTS
(2021)
Article
Fisheries
Alyssa M. Budd, Jarrod L. Guppy, Valentin Thepot, Jose A. Domingos, Dean R. Jerry
Summary: This study reveals that temperature treatment has an effect on gonadal DNA methylation and primary sexual development in sequential hermaphroditic fish, particularly with a delayed effect on the gonads of juvenile barramundi.
Article
Ecology
Brien H. Roberts, John R. Morrongiello, David L. Morgan, Alison J. King, Thor M. Saunders, Sam C. Banks, David A. Crook
Summary: Many animals exhibit partial migration, which plays a key role in shaping population demography by driving differences in growth, age at maturity, and survival.
JOURNAL OF ANIMAL ECOLOGY
(2023)
Article
Fisheries
Harriet R. Goodrich, Rod W. Wilson, Richard Smullen, Andrew C. Barnes, Craig E. Franklin
Summary: The study focused on reducing the energetic costs associated with digestion in fish by increasing the acidity of pelleted fish diets. It found that an acidified diet reduced the need for acid secretion in the stomach, prevented a post-prandial blood alkaline tide, and decreased the total energetic cost of digestion by about 45%. While there was an initial improvement in food conversion to fish growth efficiency, this improvement declined over time, indicating the need for further research on the long-term implications of feeding fish an acidified diet.
Article
Fisheries
R. Marcoli, D. B. Jones, C. Massault, A. F. Marc, M. Moran, P. J. Harrison, H. S. Cate, A. L. Lopata, D. R. Jerry
Summary: A study found that there are cellular, ultrastructural, and cellular differences between color variants of barramundi. The number and distribution of melanophores, which produce melanin, vary among the golden, silver, and black phenotypes. The findings have commercial significance for increasing the production of rare color variants.
Article
Immunology
Sunita Awate, Salma Mubarka, Roland G. Huber
Summary: Lates calcarifer, also known as Barramundi or Asian seabass, is a highly productive fish species suitable for large-scale aquaculture. However, the dense populations in aquaculture settings increase the risk of infectious diseases, which negatively impact yield. Immunization of juveniles and development of new immunization agents are crucial for improving aquaculture efficiency and food security.
Article
Fisheries
David Poppi, Michael Salini, Stephen Moore, Cedric Simon, Brett Glencross
Summary: An experiment was conducted to assess the effect of fish size on losses of protein and amino acids in barramundi. The results showed that fish size significantly influenced the losses of protein and amino acids during a fasting period of 21 days.
Article
Physiology
Kris Nilsen, Bruce R. Thompson, Natalie Zajakovski, Michael Kean, Benjamin Harris, Gary Cowin, Phil Robinson, G. Kim Prisk, Francis Thien
Summary: The study utilized He-3 MRI to investigate lung function in asthma patients and found that the areas of low-ventilated lung in asthma patients were primarily due to airway closure. The marker of airway closure Xrs (6 Hz) was a significant predictor of low-ventilated lung volume.
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Christopher N. Subasic, Esther Kuilamu, Gary Cowin, Rodney F. Minchin, Lisa M. Kaminskas
Summary: The study investigated the pharmacokinetics of PEGylated liposomal doxorubicin in rats and found no significant sex-based differences in clearance but higher doxorubicin concentrations in lymph in female rats. Immune function may contribute to interindividual variability in the pharmacokinetics of liposomes, with the exception of lymphatic exposure. Published human data also revealed no significant sex differences in PLD plasma clearance, except for patients with Kaposi's sarcoma.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Multidisciplinary Sciences
Omkar L. Patkar, Abdalla Z. Mohamed, Ashwin Narayanan, Karine Mardon, Gary Cowin, Rajiv Bhalla, Damion H. R. Stimson, Michael Kassiou, Kate Beecher, Arnauld Belmer, Ignatius Alvarez Cooper, Michael Morgan, David A. Hume, Katharine M. Irvine, Selena E. Bartlett, Fatima Nasrallah, Paul Cumming
Summary: Through experiments on rats, it was found that rats with a binge sucrose diet showed a significant increase in brain inflammation despite normal weight gain, compared to the control group. The sucrose diet-induced neuroinflammation was associated with a significant elevation of white blood cell counts.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Phillip W. Janowicz, Zachary H. Houston, Jens Bunt, Nicholas L. Fletcher, Craig A. Bell, Gary Cowin, Christopher B. Howard, Dewan Taslima, Nicholas Westra van Holthe, Amber Prior, Vanessa Soh, Saikat Ghosh, James Humphries, Pie Huda, Stephen M. Mahler, Linda J. Richards, Kristofer J. Thurecht
Summary: Personalised nanomedicine is a developing field that shows promise in targeting aggressive cancer with minimal side effects. In this study, researchers used magnetic resonance imaging techniques to determine the optimal stage at which to administer nanomedicine for treating brain tumors. The results showed that nanoparticle-delivered doxorubicin effectively reduced tumor growth and increased tumor apoptosis. This study highlights the potential of polyethylene-based nanoparticles in treating tumors with disrupted blood-brain barrier.
Article
Materials Science, Biomaterials
Yuao Wu, Gary Cowin, Shehzahdi S. Moonshi, Huong D. N. Tran, Najma Annuria Fithri, Andrew K. Whittaker, Run Zhang, Hang T. Ta
Summary: In this study, modular two-in-one nano-cocktails were synthesized for treatment of inflammatory diseases and tracking of delivery. The nano-cocktails showed potential for MR imaging and therapeutic capabilities in treating inflammatory diseases.
MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
(2021)
Article
Neurosciences
Kirat K. Chand, Stephanie M. Miller, Gary J. Cowin, Lipsa Mohanty, Jany Pienaar, Paul B. Colditz, Stella Tracey Bjorkman, Julie A. Wixey
Summary: Inflammation plays a key role in the progression of brain impairment in FGR newborns, and ibuprofen may reduce NVU disruption and brain impairment in FGR piglets. Ibuprofen treatment decreases pro-inflammatory response, enhances astrocyte interaction with blood vessels, and restores NVU integrity, improving the FGR brain microenvironment.
MOLECULAR NEUROBIOLOGY
(2022)
Article
Anesthesiology
Sue Lawrence, Stacey Llewellyn, Helen Hunt, Gary Cowin, David J. Sturgess, David Reutens
Summary: The study found that the lumbar interspinous ligament plus supraspinous ligament are biconcave axially, commonly with fat-filled gaps, particularly in the anterior region. These anatomical features may explain false or equivocal loss of resistance during epidural procedures.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2021)
Article
Physics, Multidisciplinary
Gary J. Cowin, Karine Mardon, Zachary H. Houston, Rajiv Bhalla, Damion H. R. Stimson, Kristofer J. Thurecht, Ian M. Brereton
Summary: The study utilized dynamic gadolinium-enhanced magnetic resonance - positron emission tomography to independently evaluate vascular delivery and blood brain barrier integrity in brain tumors. It also observed the dynamic changes of therapeutic agents. This method can provide important information on the alterations of therapeutic agent delivery and uptake.
FRONTIERS IN PHYSICS
(2022)
Article
Chemistry, Medicinal
Karine Mardon, Jayendra Z. Patel, Juha R. Savinainen, Damion H. R. Stimson, Caitlin R. M. Oyagawa, Natasha L. Grimsey, Mary-anne Migotto, Grace F. M. Njiru, Brett R. Hamilton, Gary Cowin, Jari Yli-Kauhaluoma, Wim Vanduffel, Idriss Blakey, Rajiv Bhalla, Christopher Cawthorne, Sofie Celen, Guy Bormans, Kristofer J. Thurecht, Muneer Ahamed
Summary: Multimodal imaging, through PET and MALDI imaging, is used to discover and validate a new probe targeting the ABHD6 enzyme. The PET ligand [18F]JZP-MA-11 is reported to have specific uptake in ABHD6-rich tissues and major brain regions, with brain uptake confirmed in a nonhuman primate study. In vivo pharmacological response upon ABHD6 inhibition is observed using MALDI imaging. These synergistic imaging efforts hold promise for improving our understanding of ABHD6-mediated endocannabinoid metabolism in peripheral and central nervous system disorders.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Otorhinolaryngology
Peter Grant Osmotherly, Gary J. Cowin, Darren A. Rivett
Summary: This study provides a detailed description of the morphology and radiological appearance of the craniovertebral ligaments using a combination of magnetic resonance (MR) imaging and fine dissection. The results show that 4.6T MR images accurately depict the structure, dimensions, and attachments of the ligaments, which are consistent with gross dissection findings.
JOURNAL OF CRANIOVERTEBRAL JUNCTION AND SPINE
(2022)
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
A. Scott, G. Cowin, K. Mardon, T. Hung, W. Lakshantha, M. DeVeer, G. Angelis, H. Hamze, A. Narayaran, G. O'Keefe, C. Dixson, S. Meikle
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Meeting Abstract
Zoology
D. M. Sivitilli, W. L. Weertman, E. L. Busch, J. F. Ullmann, J. R. Smith, D. H. Gire
INTEGRATIVE AND COMPARATIVE BIOLOGY
(2021)
Meeting Abstract
Medicine, General & Internal
G. Cowin, K. Mardon, T. Hung, W. Lakshantha, T. Sepehrizadeh, M. De Veer, G. Angelis, A. Narayanan, G. O'Keefe, C. Dixon, A. Scott, S. Meikle
INTERNAL MEDICINE JOURNAL
(2021)
Meeting Abstract
Respiratory System
K. Nilsen, B. Thompson, N. Zajakovski, M. Kean, B. Harris, G. Cowin, P. Robinson, G. Prisk, F. Thien
Meeting Abstract
Respiratory System
K. Nilsen, B. Thompson, N. Zajokvski, M. Kean, B. Harris, G. Cowin, P. Robinson, G. Prisk, F. Thien