Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest
出版年份 2015 全文链接
标题
Modeling and Prediction of Solvent Effect on Human Skin Permeability using Support Vector Regression and Random Forest
作者
关键词
<em class=EmphasisTypeItalic >in silico</em> prediction, quantitative structure–property relationship, skin permeability, solvent effect, support vector regression
出版物
PHARMACEUTICAL RESEARCH
Volume 32, Issue 11, Pages 3604-3617
出版商
Springer Nature
发表日期
2015-06-02
DOI
10.1007/s11095-015-1720-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Correlations of limiting oxygen index with structural polyphosphoester features by QSPR approaches
- (2014) Simona Funar-Timofei et al. STRUCTURAL CHEMISTRY
- Descriptor Selection Methods in Quantitative Structure–Activity Relationship Studies: A Review Study
- (2013) Mohsen Shahlaei CHEMICAL REVIEWS
- Assessing vehicle effects on skin absorption using artificial membrane assays
- (2013) Daniela Karadzovska et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Skin penetration enhancers
- (2013) Majella E. Lane INTERNATIONAL JOURNAL OF PHARMACEUTICS
- DrugBank 4.0: shedding new light on drug metabolism
- (2013) Vivian Law et al. NUCLEIC ACIDS RESEARCH
- Linear and nonlinear quantitative structure-property relationship modelling of skin permeability
- (2013) A. Khajeh et al. SAR AND QSAR IN ENVIRONMENTAL RESEARCH
- Influence of Skin Thickness on the in Vitro Permeabilities of Drugs through Sprague-Dawley Rat or Yucatan Micropig Skin
- (2012) Hiroyuki Takeuchi et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Real External Predictivity of QSAR Models. Part 2. New Intercomparable Thresholds for Different Validation Criteria and the Need for Scatter Plot Inspection
- (2012) Nicola Chirico et al. Journal of Chemical Information and Modeling
- Optimization of parameters for semiempirical methods VI: more modifications to the NDDO approximations and re-optimization of parameters
- (2012) James J. P. Stewart JOURNAL OF MOLECULAR MODELING
- Non-invasive estimate of blood glucose and blood pressure from a photoplethysmograph by means of machine learning techniques
- (2011) Enric Monte-Moreno ARTIFICIAL INTELLIGENCE IN MEDICINE
- Further exploring rm2 metrics for validation of QSPR models
- (2011) Probir Kumar Ojha et al. CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS
- Real External Predictivity of QSAR Models: How To Evaluate It? Comparison of Different Validation Criteria and Proposal of Using the Concordance Correlation Coefficient
- (2011) Nicola Chirico et al. Journal of Chemical Information and Modeling
- Comparative Studies on Some Metrics for External Validation of QSPR Models
- (2011) Kunal Roy et al. Journal of Chemical Information and Modeling
- Validated models for predicting skin penetration from different vehicles
- (2010) Taravat Ghafourian et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Modelling the effect of mixture components on permeation through skin
- (2010) T. Ghafourian et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- The application of Gaussian processes in the prediction of percutaneous absorption
- (2010) Gary P. Moss et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Role of physicochemical properties in the estimation of skin permeability:in vitrodata assessment by Partial Least-Squares Regression
- (2010) P. Chauhan et al. SAR AND QSAR IN ENVIRONMENTAL RESEARCH
- Predicting Skin Permeability from Complex Chemical Mixtures: Dependency of Quantitative Structure Permeation Relationships on Biology of Skin Model Used
- (2010) Jim E. Riviere et al. TOXICOLOGICAL SCIENCES
- Comments on the Definition of theQ2Parameter for QSAR Validation
- (2009) Viviana Consonni et al. Journal of Chemical Information and Modeling
- Nonlinear Quantitative Structure-Property Relationship Modeling of Skin Permeation Coefficient
- (2009) Brian J. Neely et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Skin Solubility Determines Maximum Transepidermal Flux for Similar Size Molecules
- (2009) Qian Zhang et al. PHARMACEUTICAL RESEARCH
- Optimisation of Cosolvent Concentration for Topical Drug Delivery – II: Influence of Propylene Glycol on Ibuprofen Permeation
- (2009) R.M. Watkinson et al. SKIN PHARMACOLOGY AND PHYSIOLOGY
- Forecasting PVT properties of crude oil systems based on support vector machines modeling scheme
- (2008) Emad A. El-Sebakhy JOURNAL OF PETROLEUM SCIENCE AND ENGINEERING
- On Some Aspects of Variable Selection for Partial Least Squares Regression Models
- (2007) Partha Pratim Roy et al. Quantitative structure-activity relationships & combinatorial science
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now