Systematic, spatial imaging of large multimolecular assemblies and the emerging principles of supramolecular order in biological systems

Combined multi-gene analysis at the RNA and protein levels in single FFPE tissue sections

(2013) Christian Ostalecki et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Murine Whole-Organ Immune Cell Populations Revealed by Multi-epitope-Ligand Cartography

(2013) Jenny Eckhardt et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perspective: Finding cancer's first principles

(2012) Robert Gatenby   NATURE

Diagnosing the decline in pharmaceutical R&D efficiency

(2012) Jack W. Scannell et al.   NATURE REVIEWS DRUG DISCOVERY

Toponome imaging system: multiplex biomarkers in oncology

(2012) Robert G. Evans et al.   TRENDS IN MOLECULAR MEDICINE

Basic research in HIV vaccinology is hampered by reductionist thinking

(2012) Marc H. V. Van Regenmortel   Frontiers in Immunology

The gain in brain: novel imaging techniques and multiplexed proteomic imaging of brain tissue ultrastructure

(2011) Kristina D Micheva et al.   CURRENT OPINION IN NEUROBIOLOGY

Interactive, Graph-based Visual Analysis of High-dimensional, Multi-parameter Fluorescence Microscopy Data in Toponomics

(2011) S. Oeltze et al.   IEEE TRANSACTIONS ON VISUALIZATION AND COMPUTER GRAPHICS

The T Cell Receptor Triggering Apparatus Is Composed of Monovalent or Monomeric Proteins

(2011) John R. James et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive catalog of European biobanks

(2011) H-Erich Wichmann et al.   NATURE BIOTECHNOLOGY

Resolving controversies on the path to Alzheimer's therapeutics

(2011) Dennis J Selkoe   NATURE MEDICINE

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

Next-generation biomarkers based on 100-parameter functional super-resolution microscopy TIS

(2011) Walter Schubert et al.   New Biotechnology

In situ localization of epidermal stem cells using a novel multi epitope ligand cartography approach

(2010) Martin Ruetze et al.   Integrative Biology

On the origin of cell functions encoded in the toponome

(2010) Walter Schubert   JOURNAL OF BIOTECHNOLOGY

Toponome Imaging System:In SituProtein Network Mapping in Normal and Cancerous Colon from the Same Patient Reveals More than Five-Thousand Cancer Specific Protein Clusters and Their Subcellular Annotation by Using a Three Symbol Code

(2010) Sayantan Bhattacharya et al.   JOURNAL OF PROTEOME RESEARCH

Comparative Multi-Epitope-Ligand-Cartography reveals essential immunological alterations in Barrett's metaplasia and esophageal adenocarcinoma

(2010) Uta Berndt et al.   Molecular Cancer

Generating recombinant antibodies to the complete human proteome

(2010) Stefan Dübel et al.   TRENDS IN BIOTECHNOLOGY

Comparative in situ topoproteome analysis reveals differences in patch test-induced eczema: cytotoxicity-dominated nickel versus pleiotrope pollen reaction

(2009) Kilian Eyerich et al.   EXPERIMENTAL DERMATOLOGY

Toponome Mapping in Prostate Cancer: Detection of 2000 Cell Surface Protein Clusters in a Single Tissue Section and Cell Type Specific Annotation by Using a Three Symbol Code

(2009) Walter Schubert et al.   JOURNAL OF PROTEOME RESEARCH

The molecular face of prostate cancer

(2009) Linda Sage   JOURNAL OF PROTEOME RESEARCH

Functional architecture of the cell nucleus: Towards comprehensive toponome reference maps of apoptosis

(2008) Walter Schubert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Applications of proteomics in the study of inflammatory bowel diseases

(2008) Philip Alex et al.   INFLAMMATORY BOWEL DISEASES

In-situ-topoproteome analysis of cutaneous lymphomas: Perspectives of assistance for dermatohistologic diagnostics by Multi Epitope Ligand Cartography (MELC)

(2008) Bernd Bonnekoh et al.   JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT

Sphingosine 1-Phosphate Modulates Spinal Nociceptive Processing

(2008) Ovidiu Coste et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Toponome Project | Human Proteinpedia is open for (free) business

(2008) Katie Cottingham   JOURNAL OF PROTEOME RESEARCH

Interlocking transcriptomics, proteomics and toponomics technologies for brain tissue analysis in murine hippocampus

(2008) Marcus Bode et al.   PROTEOMICS