The Multiple Faces of Valosin-Containing Protein-Associated Diseases: Inclusion Body Myopathy with Paget’s Disease of Bone, Frontotemporal Dementia, and Amyotrophic Lateral Sclerosis

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The Role of Autophagy: What can be Learned from the Genetic Forms of Amyotrophic Lateral Sclerosis

(2012) Livia Pasquali et al.   CNS & Neurological Disorders-Drug Targets

Clinical Trials for Neuroprotection in ALS

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Inclusion Body Myopathy With Paget Disease of Bone and Frontotemporal Dementia Linked to VCP p.Arg155Cys in a Korean Family

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A Brazilian family with hereditary inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia

(2011) R.D. Fanganiello et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

A novel exon 2 I27V VCP variant is associated with dissimilar clinical syndromes

(2011) Jonathan D. Rohrer et al.   JOURNAL OF NEUROLOGY

Pathogenic VCP/TER94 Alleles Are Dominant Actives and Contribute to Neurodegeneration by Altering Cellular ATP Level in a Drosophila IBMPFD Model

(2011) Ya-Chu Chang et al.   PLoS Genetics

A role of small heat shock protein B8 (HspB8) in the autophagic removal of misfolded proteins responsible for neurodegenerative diseases

(2010) Valeria Crippa et al.   Autophagy

Imbalances in p97 co-factor interactions in human proteinopathy

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Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone

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Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy

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The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)

(2010) Valeria Crippa et al.   HUMAN MOLECULAR GENETICS

TDP-43 Mediates Degeneration in a Novel Drosophila Model of Disease Caused by Mutations in VCP/p97

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Excessive collagen accumulation in dystrophic (mdx) respiratory musculature is independent of enhanced activation of the NF-κB pathway

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Focusing the mind on ALS: updated practice parameters

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Two Australian families with inclusion-body myopathy, Paget’s disease of bone and frontotemporal dementia: Novel clinical and genetic findings

(2010) Kishore R. Kumar et al.   NEUROMUSCULAR DISORDERS

Capturing VCP: Another Molecular Piece in the ALS Jigsaw Puzzle

(2010) Christopher E. Shaw   NEURON

Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

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VCP Associated Inclusion Body Myopathy and Paget Disease of Bone Knock-In Mouse Model Exhibits Tissue Pathology Typical of Human Disease

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ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS

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Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study

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Therapeutic targeting of signaling pathways in muscular dystrophy

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Inclusion body myopathy with Paget disease and frontotemporal dementia (IBMPFD): clinical features including sphincter disturbance in a large pedigree

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Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates

(2009) Viktor I. Korolchuk et al.   MOLECULAR CELL

A novel mutation in the VCP gene (G157R) in a german family with inclusion-body myopathy with paget disease of bone and frontotemporal dementia

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Clinical heterogeneity in 3 unrelated families linked to VCP p.Arg159His

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Valosin-containing protein disease: Inclusion body myopathy with Paget’s disease of the bone and fronto-temporal dementia

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Clinical outcome in 19 French and Spanish patients with valosin-containing protein myopathy associated with Paget’s disease of bone and frontotemporal dementia

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Valosin containing protein associated inclusion body myopathy: abnormal vacuolization, autophagy and cell fusion in myoblasts

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

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Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

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Clinical studies in familial VCP myopathy associated with Paget disease of bone and frontotemporal dementia

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Roles of VCP in human neurodegenerative disorders

(2008) Akira Kakizuka   BIOCHEMICAL SOCIETY TRANSACTIONS

VCP disease associated with myopathy, Paget disease of bone and frontotemporal dementia: Review of a unique disorder

(2008) Virginia E. Kimonis et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

UBXD7 Binds Multiple Ubiquitin Ligases and Implicates p97 in HIF1α Turnover

(2008) Gabriela Alexandru et al.   CELL

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

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Descriptive epidemiology of amyotrophic lateral sclerosis: new evidence and unsolved issues

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An Italian family with inclusion-body myopathy and frontotemporal dementia due to mutation in theVCP gene

(2007) Teresa Gidaro et al.   MUSCLE & NERVE

Inclusion body myopathy and frontotemporal dementia caused by a novel VCP mutation

(2007) Anna Bersano et al.   NEUROBIOLOGY OF AGING