Control of autophagy maturation by acid sphingomyelinase in mouse coronary arterial smooth muscle cells: protective role in atherosclerosis

Acid Sphingomyelinase Amplifies Redox Signaling in Pseudomonas aeruginosa-Induced Macrophage Apoptosis

(2014) Y. Zhang et al.   JOURNAL OF IMMUNOLOGY

Inhibition of the autophagic flux by salinomycin in breast cancer stem-like/progenitor cells interferes with their maintenance

(2013) Wen Yue et al.   Autophagy

Regulation of autophagic flux by dynein-mediated autophagosomes trafficking in mouse coronary arterial myocytes

(2013) Ming Xu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Enhancement of Autophagy by Simvastatin through Inhibition of Rac1-mTOR Signaling Pathway in Coronary Arterial Myocytes

(2013) Yu-Miao Wei et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7g

(2013) Zufeng Ding et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Recombinant Human Acid Sphingomyelinase as an Adjuvant to Sorafenib Treatment of Experimental Liver Cancer

(2013) Radoslav Savić et al.   PLoS One

Liver and Skin Histopathology in Adults With Acid Sphingomyelinase Deficiency (Niemann-Pick Disease Type B)

(2012) Beth L. Thurberg et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells

(2012) Cuihong Zhou et al.   Autophagy

The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles

(2012) P. Lacolley et al.   CARDIOVASCULAR RESEARCH

Activation of Nod-Like Receptor Protein 3 Inflammasomes Turns on Podocyte Injury and Glomerular Sclerosis in Hyperhomocysteinemia

(2012) Chun Zhang et al.   HYPERTENSION

Autophagy downregulates thrombin-induced VSMCs proliferation through lysosomal pathway

(2012) Nan Dong et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Regulation of Autophagy and Its Associated Cell Death by “Sphingolipid Rheostat”

(2012) Makoto Taniguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice

(2012) Xiang Li et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Role of CD95 in pulmonary inflammation and infection in cystic fibrosis

(2012) Katrin Anne Becker et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy

(2012) R David Sentelle et al.   Nature Chemical Biology

Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release

(2012) Dongbiao Shen et al.   Nature Communications

Acid Sphingomyelinase Gene Deficiency Ameliorates the Hyperhomocysteinemia-Induced Glomerular Injury in Mice

(2011) Krishna M. Boini et al.   AMERICAN JOURNAL OF PATHOLOGY

NAD(P)H oxidase-dependent intracellular and extracellular O2•− production in coronary arterial myocytes from CD38 knockout mice

(2011) Ming Xu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cathepsin B Overexpression Due to Acid Sphingomyelinase Ablation Promotes Liver Fibrosis in Niemann-Pick Disease

(2011) Anna Moles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adeno-associated virus-mediated expression of acid sphingomyelinase decreases atherosclerotic lesion formation in apolipoprotein E−/− mice

(2011) Andrew J. Leger et al.   JOURNAL OF GENE MEDICINE

Kinase suppressor of Ras-1 protects against pulmonary Pseudomonas aeruginosa infections

(2011) Yang Zhang et al.   NATURE MEDICINE

Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activation

(2010) Margaret A. Park et al.   CANCER BIOLOGY & THERAPY

Protein Phosphatase 2A (PP2A) Holoenzymes Regulate Death-associated Protein Kinase (DAPK) in Ceramide-induced Anoikis

(2010) Ryan C. Widau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

7-Ketocholesterol and cholesterol-5α,6α-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways

(2010) Po Lin Liao et al.   TOXICOLOGY LETTERS

Control of cell proliferation in atherosclerosis: insights from animal models and human studies

(2009) J. J. Fuster et al.   CARDIOVASCULAR RESEARCH

Macrophage Sphingomyelin Synthase 2 Deficiency Decreases Atherosclerosis in Mice

(2009) Jing Liu et al.   CIRCULATION RESEARCH

Cell-permeable ceramides act as novel regulators of U937 cell–cell adhesion mediated by CD29, CD98, and CD147

(2009) Yong Gyu Lee et al.   IMMUNOBIOLOGY

The effects of dynein inhibition on the autophagic pathway in glioma cells

(2009) Midori Yamamoto et al.   NEUROPATHOLOGY

Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells

(2008) Susann Patschan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Lysosomal Targeting and Trafficking of Acid Sphingomyelinase to Lipid Raft Platforms in Coronary Endothelial Cells

(2008) Si Jin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Acid Sphingomyelinase Promotes Lipoprotein Retention Within Early Atheromata and Accelerates Lesion Progression

(2008) Cecilia M. Devlin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Ceramide-enriched membrane domains—Structure and function

(2008) Yang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Acid sphingomyelinase is required for efficient phago-lysosomal fusion

(2008) Michael Schramm et al.   CELLULAR MICROBIOLOGY

Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathway

(2008) Youssef H. Zeidan et al.   JOURNAL OF CELL BIOLOGY

Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes

(2008) K. Trajkovic et al.   SCIENCE

The Itinerary of Autophagosomes: From Peripheral Formation to Kiss-and-Run Fusion with Lysosomes

(2008) Luca Jahreiss et al.   TRAFFIC

Acutely reduced locomotor activity is a major contributor to Western diet-induced obesity in mice

(2007) Mikael Bjursell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM