A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension

Metabolic Gene Remodeling and Mitochondrial Dysfunction in Failing Right Ventricular Hypertrophy Secondary to Pulmonary Arterial Hypertension

(2012) Jose Gomez-Arroyo et al.   Circulation-Heart Failure

Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

(2012) G Sutendra et al.   ONCOGENE

The monocrotaline model of pulmonary hypertension in perspective

(2011) Jose G. Gomez-Arroyo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Pyruvate dehydrogenase inhibition by the inflammatory cytokine TNFα contributes to the pathogenesis of pulmonary arterial hypertension

(2011) Gopinath Sutendra et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Progressive Right Ventricular Dysfunction in Patients With Pulmonary Arterial Hypertension Responding to Therapy

(2011) Mariëlle C. van de Veerdonk et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The Role of Nogo and the Mitochondria-Endoplasmic Reticulum Unit in Pulmonary Hypertension

(2011) G. Sutendra et al.   Science Translational Medicine

Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats

(2010) Harm J. Bogaard et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The role of mitochondria in pulmonary vascular remodeling

(2010) Peter Dromparis et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Fatty Acid Oxidation and Malonyl-CoA Decarboxylase in the Vascular Remodeling of Pulmonary Hypertension

(2010) G. Sutendra et al.   Science Translational Medicine

The Right Ventricle Under Pressure

(2009) Harm J. Bogaard et al.   CHEST

Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure

(2009) Harm J. Bogaard et al.   CIRCULATION

The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle

(2009) Lin Piao et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Right Ventricular Function in Cardiovascular Disease, Part I

(2008) François Haddad et al.   CIRCULATION

Right Ventricular Function in Cardiovascular Disease, Part II

(2008) François Haddad et al.   CIRCULATION

A dynamic and chamber-specific mitochondrial remodeling in right ventricular hypertrophy can be therapeutically targeted

(2008) Jayan Nagendran et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY