Aptamers: multifunctional molecules for biomedical research

In vivo SELEX for Identification of Brain-penetrating Aptamers

(2013) Congsheng Cheng et al.   Molecular Therapy-Nucleic Acids

An electronic channel switching-based aptasensor for ultrasensitive protein detection

(2012) Hongbo Li et al.   ANALYTICA CHIMICA ACTA

An RNA Aptamer-Based Microcantilever Sensor To Detect the Inflammatory Marker, Mouse Lipocalin-2

(2012) Lijie Zhai et al.   ANALYTICAL CHEMISTRY

Targeting von Willebrand factor as a novel anti-platelet therapy; Application of ARC1779, an Anti-vWF aptamer, against thrombotic risk

(2012) Ok-Nam Bae   ARCHIVES OF PHARMACAL RESEARCH

Aptamer-Mediated Blockade of IL4R  Triggers Apoptosis of MDSCs and Limits Tumor Progression

(2012) F. Roth et al.   CANCER RESEARCH

Therapeutic RNA aptamers in clinical trials

(2012) Padma Sundaram et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine

(2012) Mao Ye et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Life's Simple Measures: Unlocking the Proteome

(2012) Edward Brody et al.   JOURNAL OF MOLECULAR BIOLOGY

UCLA1, a Synthetic Derivative of a gp120 RNA Aptamer, Inhibits Entry of Human Immunodeficiency Virus Type 1 Subtype C

(2012) H. T. Mufhandu et al.   JOURNAL OF VIROLOGY

Use of Cell-SELEX to Generate DNA Aptamers as Molecular Probes of HPV-Associated Cervical Cancer Cells

(2012) Jessica C. Graham et al.   PLoS One

Aptamers in Virology: Recent Advances and Challenges

(2012) Jennifer M. Binning et al.   Frontiers in Microbiology

Current Progress of RNA Aptamer-Based Therapeutics

(2012) Jiehua Zhou et al.   Frontiers in Genetics

Microfluidic Electrochemical Aptameric Assay Integrated On-Chip: A Potentially Convenient Sensing Platform for the Amplified and Multiplex Analysis of Small Molecules

(2011) Yan Du et al.   ANALYTICAL CHEMISTRY

Aptamer selection for the detection of Escherichia coli K88

(2011) Hua Li et al.   CANADIAN JOURNAL OF MICROBIOLOGY

A Novel Aptamer Developed for Breast Cancer Cell Internalization

(2011) Kejing Zhang et al.   ChemMedChem

Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons

(2011) X. Ni et al.   CURRENT MEDICINAL CHEMISTRY

Aptamer-based modulation of blood coagulation

(2011) G. Mayer et al.   Hamostaseologie

Aptamer inhibits Mycobacterium tuberculosis (H37Rv) invasion of macrophage

(2011) Fan Chen et al.   MOLECULAR BIOLOGY REPORTS

Functional-DNA–Based Nanoscale Materials and Devices for Sensing Trace Contaminants in Water

(2011) Daryl P. Wernette et al.   MRS BULLETIN

Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates

(2011) Mark A. Ditzler et al.   NUCLEIC ACIDS RESEARCH

Multiple conformations of SAM-II riboswitch detected with SAXS and NMR spectroscopy

(2011) Bin Chen et al.   NUCLEIC ACIDS RESEARCH

Sensing of Transcription Factor through Controlled-Assembly of Metal Nanoparticles Modified with Segmented DNA Elements

(2010) Yen Nee Tan et al.   ACS Nano

Specific Colorimetric Detection of Proteins Using Bidentate Aptamer-Conjugated Polydiacetylene (PDA) Liposomes

(2010) Yun Kyung Jung et al.   ADVANCED FUNCTIONAL MATERIALS

Highly Modular Structure and Ligand Binding by Conformational Capture in a Minimalistic Riboswitch

(2010) Elke Duchardt-Ferner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of cell adhesion by anti-P-selectin aptamer: a new potential therapeutic agent for sickle cell disease

(2010) D. R. Gutsaeva et al.   BLOOD

A New Paradigm for Aptamer Therapeutic AS1411 Action: Uptake by Macropinocytosis and Its Stimulation by a Nucleolin-Dependent Mechanism

(2010) E. M. Reyes-Reyes et al.   CANCER RESEARCH

Simultaneous electrochemical detection of both PSMA (+) and PSMA (−) prostate cancer cells using an RNA/peptide dual-aptamer probe

(2010) Kyoungin Min et al.   CHEMICAL COMMUNICATIONS

Ligand-induced conformational capture of a synthetic tetracycline riboswitch revealed by pulse EPR

(2010) D. Wunnicke et al.   RNA

Aptamers and the RNA World, Past and Present

(2010) L. Gold et al.   Cold Spring Harbor Perspectives in Biology

Aptamer-Based Microfluidic Device for Enrichment, Sorting, and Detection of Multiple Cancer Cells

(2009) Ye Xu et al.   ANALYTICAL CHEMISTRY

Reversible Cell-Specific Drug Delivery with Aptamer-Functionalized Liposomes

(2009) Zehui Cao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aptamers against prion proteins and prions

(2009) Sabine Gilch et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A liposome-based nanostructure for aptamer directed delivery

(2009) Huaizhi Kang et al.   CHEMICAL COMMUNICATIONS

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Modifications Incorporated in CpG Motifs of Oligodeoxynucleotides Lead to Antagonist Activity of Toll-like Receptors 7 and 9

(2009) Dong Yu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Viral Capsid DNA Aptamer Conjugates as Multivalent Cell-Targeting Vehicles

(2009) Gary J. Tong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular recognition of acute myeloid leukemia using aptamers

(2009) K Sefah et al.   LEUKEMIA

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

In vivo selection of tumor-targeting RNA motifs

(2009) Jing Mi et al.   Nature Chemical Biology

Antimetastatic Potential of PAI-1–Specific RNA Aptamers

(2009) Charlene M. Blake et al.   OLIGONUCLEOTIDES

In vitro selection of RNA aptamers against a conserved region of the Plasmodium falciparum erythrocyte membrane protein 1

(2009) Anders Barfod et al.   PARASITOLOGY RESEARCH

Carbon Nanotubes Protect DNA Strands during Cellular Delivery

(2008) Yanrong Wu et al.   ACS Nano

Cancer Cell Targeting Using Multiple Aptamers Conjugated on Nanorods

(2008) Yu-Fen Huang et al.   ANALYTICAL CHEMISTRY

Aptasensors for detection of microbial and viral pathogens

(2008) Edith Torres-Chavolla et al.   BIOSENSORS & BIOELECTRONICS

The Nucleolin Targeting Aptamer AS1411 Destabilizes Bcl-2 Messenger RNA in Human Breast Cancer Cells

(2008) S. Soundararajan et al.   CANCER RESEARCH

Ultrasensitive colorimetric detection of protein by aptamer–Au nanoparticles conjugates based on a dot-blot assay

(2008) Yuling Wang et al.   CHEMICAL COMMUNICATIONS

Post-SELEX Chemical Optimization of a Trypanosome-Specific RNA Aptamer

(2008) H. Goringer et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Cell-Specific Induction of Apoptosis by Rationally Designed Bivalent Aptamer-siRNA Transcripts Silencing Eukaryotic Elongation Factor 2

(2008) Ulrich Wullner et al.   CURRENT CANCER DRUG TARGETS

Myeloid-Derived Suppressor Cells in Inflammatory Bowel Disease: A New Immunoregulatory Pathway

(2008) Lydia A. Haile et al.   GASTROENTEROLOGY

One-Step, Room Temperature, Colorimetric Detection of Mercury (Hg2+) Using DNA/Nanoparticle Conjugates

(2008) Xuejia Xue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY

Nanoscale Patterns of Oligonucleotides Formed by Electrohydrodynamic Jet Printing with Applications in Biosensing and Nanomaterials Assembly

(2008) Jang-Ung Park et al.   NANO LETTERS

Aptamers that recognize drug-resistant HIV-1 reverse transcriptase

(2008) N. Li et al.   NUCLEIC ACIDS RESEARCH

Phototoxic aptamers selectively enter and kill epithelial cancer cells

(2008) Cátia S. M. Ferreira et al.   NUCLEIC ACIDS RESEARCH

Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases

(2008) D. Michalowski et al.   NUCLEIC ACIDS RESEARCH

Novel Aptamer Inhibitors of Human Immunodeficiency Virus Reverse Transcriptase

(2008) Jeffrey J. DeStefano et al.   OLIGONUCLEOTIDES

Aptamer-based endocytosis of a lysosomal enzyme

(2008) C.-h. B. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An aptamer that neutralizes R5 strains of HIV-1 binds to core residues of gp120 in the CCR5 binding site

(2008) Carla Cohen et al.   VIROLOGY

Cell-Specific Internalization Study of an Aptamer from Whole Cell Selection

(2007) Zeyu Xiao et al.   CHEMISTRY-A EUROPEAN JOURNAL