mTOR links oncogenic signaling to tumor cell metabolism

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Glucose Addiction of TSC Null Cells Is Caused by Failed mTORC1-Dependent Balancing of Metabolic Demand with Supply

(2010) Andrew Y. Choo et al.   MOLECULAR CELL

TOR-dependent control of autophagy: biting the hand that feeds

(2009) Thomas P Neufeld   CURRENT OPINION IN CELL BIOLOGY

Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

(2009) Zachary T. Schafer et al.   NATURE

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Common corruption of the mTOR signaling network in human tumors

(2009) S Menon et al.   ONCOGENE

Direct control of mitochondrial function by mTOR

(2009) Arvind Ramanathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

EGFR Signaling Through an Akt-SREBP-1-Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy

(2009) D. Guo et al.   Science Signaling

The Pharmacology of mTOR Inhibition

(2009) D. A. Guertin et al.   Science Signaling

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Skeletal Muscle-Specific Ablation of raptor, but Not of rictor, Causes Metabolic Changes and Results in Muscle Dystrophy

(2008) C. Florian Bentzinger et al.   Cell Metabolism

Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer

(2008) Sigrun Langbein et al.   INTERNATIONAL JOURNAL OF CANCER

Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis

(2008) Umut Ozcan et al.   MOLECULAR CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

SREBPs: the crossroads of physiological and pathological lipid homeostasis

(2008) Rajendra Raghow et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM