期刊
JOURNAL OF MOLECULAR ENDOCRINOLOGY
卷 51, 期 3, 页码 T51-T59出版社
BIOSCIENTIFICA LTD
DOI: 10.1530/JME-13-0217
关键词
obesity; breast cancer; aromatase; inflammation; PGE2
资金
- NHMRC (Australia) [GNT1005735, GNT1007714, GNT0550900]
- Victorian Government, through the Victorian Cancer Agency
- Victorian Breast Cancer Research Consortium
- Victorian Government Operational Infrastructure Support Program
Obesity is now recognised to be an inflammatory condition in which dysregulated metabolism plays an integral role. Inflammatory mediators regulate aromatase expression in the human breast as one mechanism whereby they increase the risk of breast cancer, especially in women who are obese.
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