Molecular pathology and genetics of pancreatic endocrine tumours

The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

(2012) Jing Huang et al.   NATURE

Pancreatic endocrine tumours: mutational and immunohistochemical survey of protein kinases reveals alterations in targetable kinases in cancer cell lines and rare primaries

(2011) V. Corbo et al.   ANNALS OF ONCOLOGY

New treatment strategies in advanced neuroendocrine tumours

(2011) Thomas Walter et al.   DIGESTIVE AND LIVER DISEASE

Src kinase activity coordinates cell adhesion and spreading with activation of mammalian target of rapamycin in pancreatic endocrine tumour cells

(2011) Alessia Di Florio et al.   ENDOCRINE-RELATED CANCER

Identification of Cancer Stem Cells in Human Gastrointestinal Carcinoid and Neuroendocrine Tumors

(2011) Puja Gaur et al.   GASTROENTEROLOGY

Metastatic and Locally Advanced Pancreatic Endocrine Carcinomas: Analysis of Factors Associated With Disease Progression

(2011) Francesco Panzuto et al.   JOURNAL OF CLINICAL ONCOLOGY

Promising Advances in the Treatment of Malignant Pancreatic Endocrine Tumors

(2011) Robert T. Jensen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors

(2011) Eric Raymond et al.   NEW ENGLAND JOURNAL OF MEDICINE

Everolimus for Advanced Pancreatic Neuroendocrine Tumors

(2011) James C. Yao et al.   NEW ENGLAND JOURNAL OF MEDICINE

DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors

(2011) Y. Jiao et al.   SCIENCE

Inherited pancreatic endocrine tumor syndromes: Advances in molecular pathogenesis, diagnosis, management, and controversies

(2010) Robert T. Jensen et al.   CANCER

The Tumor Suppressor Protein Menin Inhibits AKT Activation by Regulating Its Cellular Localization

(2010) Yan Wang et al.   CANCER RESEARCH

MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases

(2010) Vincenzo Corbo et al.   ENDOCRINE-RELATED CANCER

mTOR expression and activity patterns in gastroenteropancreatic neuroendocrine tumours

(2010) A. Kasajima et al.   ENDOCRINE-RELATED CANCER

Analysis of next-generation genomic data in cancer: accomplishments and challenges

(2010) L. Ding et al.   HUMAN MOLECULAR GENETICS

Chromosome 3p alterations in pancreatic endocrine neoplasia

(2010) Eliana Amato et al.   VIRCHOWS ARCHIV

Loss of Membrane Localization and Aberrant Nuclear E-cadherin Expression Correlates With Invasion in Pancreatic Endocrine Tumors

(2009) Runjan Chetty et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Pancreatic Endocrine Microadenomatosis in Patients With von Hippel-Lindau Disease

(2009) Martine Pé rigny et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

KIT is an Independent Prognostic Marker for Pancreatic Endocrine Tumors

(2009) Lizhi Zhang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Expression of an activated mammalian target of rapamycin (mTOR) in gastroenteropancreatic neuroendocrine tumors

(2009) Takashi Shida et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors

(2009) A M Schmitt et al.   ENDOCRINE-RELATED CANCER

Pancreatic Endocrine Tumors: Expression Profiling Evidences a Role for AKT-mTOR Pathway

(2009) Edoardo Missiaglia et al.   JOURNAL OF CLINICAL ONCOLOGY

Endocrine Pancreatic Tumors in von Hippel-Lindau Disease

(2009) Olivier Corcos et al.   PANCREAS

Changing Incidence of Pancreatic Neoplasms

(2009) Timothy L. Fitzgerald et al.   PANCREAS

Defining molecular classifications and targets in gastroenteropancreatic neuroendocrine tumors through DNA microarray analysis

(2008) E.-M. Duerr et al.   ENDOCRINE-RELATED CANCER

Gastrointestinal Neuroendocrine Tumors: Pancreatic Endocrine Tumors

(2008) David C. Metz et al.   GASTROENTEROLOGY

Tuberous sclerosis

(2008) Paolo Curatolo et al.   LANCET

The tuberous sclerosis gene products hamartin and tuberin are multifunctional proteins with a wide spectrum of interacting partners

(2008) Margit Rosner et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The mTOR pathway and its role in human genetic diseases

(2008) M ROSNER et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Multiple endocrine neoplasia type 1 (MEN1): analysis of 1336 mutations reported in the first decade following identification of the gene

(2007) Manuel C. Lemos et al.   HUMAN MUTATION