Article
Biochemistry & Molecular Biology
Bozhi Tan, Yao Li, Xu Fei, Jing Tian, Longquan Xu, Yi Wang
Summary: The synthesis efficiency and side reactions of Octenyl succinic anhydride (OSA) starch can be improved by using lipase immobilized on polydopamine magnetic hydrogel microspheres (PMHM) as a biocatalyst. The prepared L-PMHM can be uniformly dispersed in starch slurry, leading to full contact between lipase and starch. L-PMHM exhibits better affinity to the substrate and achieves a higher degree of substitution compared to free lipase. Moreover, L-PHMM can maintain its activity after multiple reuses and can be easily separated from the product.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Huai N. Cheng, Atanu Biswas, Sanghoon Kim, Carlucio R. Alves, Roselayne F. Furtado
Summary: Xylan, a major type of hemicellulose, has been successfully derivatized to produce hydrophobically modified derivatives with confirmed structures. These xylan derivatives increase the structural diversity of xylan, providing more options for developing new applications.
Article
Biotechnology & Applied Microbiology
Thiago de Sousa Fonseca, Ulisses Marcondes Freire de Oliveira, Maria da Conceicao Ferreira de Oliveira, Telma Leda Gomes de Lemos, Marcos Reinaldo da Silva, Nathalia Saraiva Rios, Luciana Rocha Barros Goncalves, Marcos Carlos de Mattos
Summary: The study investigated the immobilization of Amano lipase AK from P. fluorescens on different chitosan-containing supports, with lower molecular weight chitosan and chitosan lower molecular weight/sodium alginate showing the highest immobilization yields and activity results. In the kinetic resolution process, the most efficient derivatives were lipase immobilized on chitosan average molecular weight and chitosan low molecular weight/sodium alginate, yielding high enantiomeric excess and conversion rates for the synthesis of a drug used in Parkinson's disease treatment.
BIOPROCESS AND BIOSYSTEMS ENGINEERING
(2021)
Article
Chemistry, Physical
Anna Morandini, Arianna Rossetti, Alessandro Sacchetti
Summary: This study presents a novel biocatalyzed pathway for the preparation of a chiral amine precursor through resolution study of a key alcohol intermediate.
Article
Biochemistry & Molecular Biology
Gordana Gojgic-Cvijovic, Dragica Jakovljevic, Ljiljana Zivkovic, Vladan Cosovic, Vladimir Pavlovic, Ivana Nikolic, Nikola Maravic, Ljubica Dokic
Summary: In this study, levan from Bacillus licheniformis NS032 was modified with octenyl succinic anhydride (OSA) in an aqueous medium, and the properties of the resulting derivatives were investigated. The optimum conditions for the synthesis reaction were found to be 40 degrees C and a polysaccharide slurry concentration of 30%. The derivatives with degrees of substitution of 0.025 and 0.036 exhibited retained porous structure and better colloidal stability compared to the native polysaccharide. These OSA-modified levans have the potential to be used in new formulations of emulsion-based systems.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Guantian Li, Fan Zhu
Summary: Nonenyl succinic anhydride (NSA) modification of starch can adjust physicochemical properties, enhance emulsifying capacity, and serve as potential Pickering emulsion stabilizers. Starch modification with a DS of 0.0359 has the highest emulsifying capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Jia Guo, Hao-Ran Ma, Wen-Bin Xiong, Luoyi Fan, You-Yun Zhou, Henry N. C. Wong, Jian-Fang Cui
Summary: An efficient kinetic resolution of alkyl allylic alcohols has been achieved through an iridium-catalyzed enantioselective alkynylation reaction. The method allows for the synthesis of chiral 1,4-enynes with various functional groups and unreacted enantioenriched allylic alcohols. It is particularly effective for preparing optically pure alkyl allylic alcohols that are difficult to access via other asymmetric reactions.
Article
Chemistry, Applied
Huijing Chen, Fuquan Chen, Qiong Xiao, Menghao Cai, Qiuming Yang, Huifen Weng, Anfeng Xiao
Summary: The novel amphiphilic agar modified with octenyl succinic anhydride (OSAR) showed higher transparency and freeze-thaw stability, as well as improved emulsion stability and oil loading capacity compared to native agar (NA). With DS values of 0.06 and 0.12, OSAR exhibited increased gel transparency and decreased syneresis, lower interface tension and average molecular weight, decreased thermal stability, enhanced gel springiness, more liquid-like properties with low gel strength, and lower turbidity and melting temperatures than NA.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Multidisciplinary
Jiang Dai, Wei Xiong, Dong-Yu Li, Zhongzheng Cai, Jian-Bo Zhu
Summary: By combining two stereogenic elements, we have successfully designed a series of bifunctional thiourea-based organocatalysts, which enable stereoselective polymerization of lactide to produce iso-enriched polylactide.
CHEMICAL COMMUNICATIONS
(2023)
Article
Energy & Fuels
Mingrong Chen, Xuan Meng, Naiwang Liu, Li Shi
Summary: The addition of Co as a promoter can improve the hydrogenation performance of NiCo/Clay catalysts, maintaining catalyst activity and avoiding deactivation.
Article
Multidisciplinary Sciences
Xiaoqian Gao, Xinli Tong, Yi Zhang, Song Xue
Summary: In this study, succinic anhydride (SAN) was directly synthesized from bio-based furanic platform compounds using a visible light-induced oxygenation process. The photocatalyst m-tetraphenyl porphyrin (H2TPP) and molecular oxygen were employed as the catalyst and oxidant, respectively. The conversion of furoic acid (FAC) to SAN achieved a 99.9% conversion with 97.8% selectivity under optimal conditions. The selectivity of the product can be controlled by tuning the light intensity and time.
Article
Chemistry, Physical
Jian Zhang, Mingyang Song, Weijun Tang, Dong Xue, Jianliang Xiao, Huaming Sun, Chao Wang
Summary: Converting racemic compounds to enantioenriched products is a common method in accessing chiral molecules. In this study, a kinetic resolution method is used to transform racemic allylic alcohols into chiral compounds, with good yields and stereoselectivities.
Review
Chemistry, Applied
Li-Cheng Yang, Heping Deng, Hans Renata
Summary: This article summarizes the chemoenzymatic and biocatalytic methodologies for DKR developed in the past decade, highlighting their applications in the preparation of active pharmaceutical ingredients and emerging paradigms.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2022)
Article
Chemistry, Physical
Marie-Helene Pietraru, Nicolas Lentz, Louise Ponsard, Emmanuel Nicolas, Thibault Cantat
Summary: In order to reduce our reliance on fossil feedstock, alternative sources for polymeric materials have been sought in recent years. This study presents a new approach to the formation of a useful monomer for polyesters, succinic anhydride, through the catalytic carbonylation of bio-sourced acrylic acid. The use of an Earth-abundant metal catalyst, [Co-2(CO)(8)], along with a bidentate ligand, 1,2-bis(dicyclohexylphosphino)ethane (dcpe), and H-2, successfully tackles the challenging carbonylation of unsaturated carboxylic acids.
Article
Chemistry, Physical
Jiandian Wang, Changyong Sun, Wenjun Xia, Zhou Cao, Guangzhe Sheng, Xiaowei Xie
Summary: A 0.33 wt% Pd/BN catalyst has been found to exhibit high activity and selectivity for the liquid-phase selective hydrogenation of maleic anhydride to succinic anhydride at room temperature. The adsorption properties of the support and its electronic interaction with Pd play an important role in determining the catalytic performance.
APPLIED CATALYSIS A-GENERAL
(2022)