Article
Nutrition & Dietetics
Ramon V. Cortez, Andrea Fernandes, Luiz Gustavo Sparvoli, Marina Padilha, Rubens Feferbaum, Corintio Mariani Neto, Carla R. Taddei
Summary: The oropharyngeal administration of colostrum has an impact on the establishment of preterm infants' oral microbiota, leading to changes in the relative abundance of different bacterial species, with time being a key factor in oral modulation in early life.
Review
Pediatrics
Mengyue Huo, Chunli Liu, Hua Mei, Yuheng Zhang, Chunzhi Liu, Dan Song, Yayu Zhang, Yanbo Zhang, Chun Xin
Summary: Oropharyngeal administration of colostrum can reduce the incidence of necrotizing enterocolitis, late-onset sepsis, and ventilator-associated pneumonia in preterm infants, shorten the time to reach full enteral feeds and duration of hospital stay, and increase the rate of weight gain.
FRONTIERS IN PEDIATRICS
(2022)
Article
Nursing
Zhen Yan Fu, Chi Huang, Lei Lei, Li Cheng Chen, Li Juan Wei, Jiao Zhou, Ming Tao, Ming Tao Quan, Yi Huang
Summary: Oropharyngeal colostrum administration can reduce complications in preterm infants and shorten the time to full enteral feeding.
INTERNATIONAL JOURNAL OF NURSING STUDIES
(2023)
Article
Multidisciplinary Sciences
Li-Lian Chen, Jie Liu, Xiao-He Mu, Xi-Yang Zhang, Chuan-Zhong Yang, Xiao-Yun Xiong, Mei-Qi Wang
Summary: The aim of this study was to investigate the impact of oropharyngeal mother's milk administration on salivary secretory immunoglobulin A (sIgA) levels in preterm infants fed by gastric tube. The results showed that oropharyngeal mother's milk administration can improve the salivary sIgA levels of preterm infants.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Silvia Romero-Maldonado, Diana Mercedes Soriano-Becerril, Perla Karina Garcia-May, Enrique Reyes-Munoz, Eudoxia Georgina Munoz-Ortiz, Sandra Carrera-Muinos, Martha Lucia Granados-Cepeda, Jorge Arturo Cardona-Perez, Elsa Castro-Millan, Enrique Segura-Cervantes, Guillermo Ceballos, Araceli Montoya-Estrada
Summary: The study suggests that oropharyngeal administration of colostrum can increase serum IgA concentration, shorten the time to complete enteral feeding and reach birth weight, and reduce the total days of hospitalization in premature newborns.
FRONTIERS IN PEDIATRICS
(2022)
Article
Pediatrics
Na Wang, Jia Zhang, Zhangbin Yu, Xudong Yan, Lian Zhang, Haibo Peng, Cheng Chen, Rui Li
Summary: Oropharyngeal administration of colostrum (OAC) has immune-stimulating effects on oropharyngeal-associated lymphoid tissue and can promote gastrointestinal tract maturation in preterm infants. This study aims to assess changes in gut microbiota and metabolites in very preterm infants after OAC. The findings may improve health outcomes of preterm infants by establishing targeted gut microbiota in future studies.
Article
Pediatrics
Pranav Jani, Umesh Mishra, Julia Buchmayer, Karen Walker, Duygu Gozen, Rajesh Maheshwari, Daphne D'cruz, Krista Lowe, Audrey Wright, James Marceau, Mihaela Culcer, Archana Priyadarshi, Adrienne Kirby, James E. Moore, Ju Lee Oei, Vibhuti Shah, Umesh Vaidya, Abdelmoneim Khashana, Sunit Godambe, Fook Choe Cheah, Wenhao Zhou, Hu Xiaojing, Muneerah Satardien
Summary: There is significant variation in thermoregulation and golden hour practices for extremely preterm infants based on geographic region, country's income status, and lowest gestational age. Efforts should be made to reduce practice variation and align with international guidelines.
PEDIATRIC RESEARCH
(2023)
Article
Obstetrics & Gynecology
Xiao-chun Chen, Yan-fen Tong, Zi-min Han, Zhen-lang Lin
Summary: Early oropharyngeal administration of colostrum can improve immune function and reduce the risk of feeding intolerance and NEC in ELBWI on mechanical ventilation.
BREASTFEEDING MEDICINE
(2021)
Article
Nutrition & Dietetics
Amanda de Paula Silva, Raphaela Correa Monteiro Machado, Barbara Folino Nascimento, Leticia Vitoria Souza da Cunha, Patricia de Carvalho Padilha
Summary: This study analyzed the clinical outcomes of very low-birth-weight infants receiving oropharyngeal administration of colostrum (OAC) and found that OAC was associated with a shorter time to recover birth weight and time to full enteral feeding.
Article
Obstetrics & Gynecology
Xia OuYang, Chang-Yi Yang, Wen-Long Xiu, Yan-Hua Hu, Su-Su Mei, Qin Lin
Summary: Oropharyngeal administration of colostrum helps reduce the incidence of NEC and late-onset sepsis in preterm infants, shorten the time to achieve full enteral feeding, and is a safe NICU procedure.
INTERNATIONAL BREASTFEEDING JOURNAL
(2021)
Article
Obstetrics & Gynecology
Nancy A. A. Rodriguez, Fernando Moya, John Landino, Adel Zauk, Preetha Prazad, Jorge Perez, Maximo Vento, Erika Claud, Chi-hsiung Wang, Michael S. Caplan
Summary: Oropharyngeal therapy with mother's own milk (OPT-MOM) did not reduce late-onset sepsis (L-OS), necrotizing enterocolitis (NEC) or death in preterm infants. However, there was a trend towards reduced length of stay and improved nutritional outcomes in the group receiving OPT-MOM.
JOURNAL OF PERINATOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Masato Ito, Shin Kato, Makoto Saito, Naoyuki Miyahara, Hirokazu Arai, Fumihiko Namba, Erika Ota, Hidehiko Nakanishi
Summary: This scoping review aimed to screen available evidence regarding perinatal risk factors associated with the development and severity of bronchopulmonary dysplasia (BPD). The results identified several risk factors for BPD, including male sex, maternal hypertensive disorders of pregnancy, low gestational age, small-for-gestational-age birth weight, and mechanical ventilation. Rating: 8 out of 10.
Review
Nutrition & Dietetics
Jogender Kumar, Jitendra Meena, Ankit Ranjan, Praveen Kumar
Summary: This systematic review examined the effect of oropharyngeal application of colostrum or mother's own milk on preterm infants, and found that it can reduce the risk of infection and necrotizing enterocolitis, and has benefits in early feeding.
Article
Medicine, General & Internal
Liron Borenstein-Levin, Noa Avishay, Orit Soffer, Shmuel Arnon, Arieh Riskin, Gil Dinur, Karen Lavie-Nevo, Ayala Gover, Amir Kugelman, Ori Hochwald
Summary: Extremely low birth weight (ELBW) premature infants are at risk of hypocarbia and hypercarbia. This study evaluates the correlation between transcutaneous CO2 (TcCO2) monitoring and blood gas CO2 (bgCO2) measurements in ELBW infants. The results show a moderate correlation and good agreement between TcCO2 and bgCO2 values in the 25-70 mmHg TcCO2 range. TcCO2 can be used as a complementary tool to assess CO2 levels and trends in premature infants, but blood gas sampling is still necessary.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Pediatrics
Nadege Bourgeois-Nicolaos, Alexandre Raynor, Shivani Shankar-Aguilera, Eden Schwartz, Florence Doucet-Populaire, Daniele De Luca
Summary: Oral care with breast milk significantly increases local immune defense markers in extremely preterm infants, but has no effect on colonization of bacteria responsible for VAP.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)
Article
Pediatrics
Ji Hyun Kim, Juyoung Lee, Dong Hyun Kim, Ji Young Park, Hyunju Lee, Hee Gyung Kang, Yo Han Ahn
Summary: About one-fourth of infantile UTI cases were ESBL-positive. Prenatal antibiotic exposure of mothers and Klebsiella species were associated with community-acquired UTI caused by ESBL-positive bacteria.
PEDIATRIC NEPHROLOGY
(2022)
Article
Pediatrics
Juyoung Lee, Vilhelmiina Parikka, Liisa Lehtonen, Hanna Soukka
Summary: The study showed that skin-to-skin contact stabilized and improved respiratory physiology in mechanically ventilated preterm infants, reducing the work of breathing and the need for backup ventilation during neurally adjusted ventilatory assist.
PEDIATRIC RESEARCH
(2022)
Letter
Pediatrics
Ju Sun Heo, Ee-Kyung Kim, Sae Yun Kim, In Gyu Song, Young Mi Yoon, Hannah Cho, Eun Sun Lee, Seung Han Shin, Byung-Mo Oh, Hyung Ik Shin, Han-Suk Kim
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION
(2023)
Article
Nutrition & Dietetics
Ji Young Lee, Hyun Jung Shin, Hye Jung Bae, Yun Hee Jo, Yoon Sook Cho, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim
Summary: Selenium deficiency is common in neonates and infants receiving long-term PN, with about 53.9% of them being deficient. The increase in serum selenium concentration is proportional to the dose of IV selenium administered, suggesting the importance of supplying an appropriate dose of IV selenium based on the degree of selenium deficiency.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION
(2022)
Article
Pediatrics
Seong Phil Bae, Ee-Kyung Kim, Jungha Yun, Young Mi Yoon, Seung Han Shin, Su Yeon Park
Summary: This study investigated whether ROP requiring treatment is associated with postnatal growth failure in VLBW infants. The results showed that ROP requiring treatment was associated with poor head circumference growth, but not with weight and length.
Article
Multidisciplinary Sciences
In Gyu Song, Han-Suk Kim, Yoon-Min Cho, You-na Lim, Duk-Soo Moon, Seung Han Shin, Ee-Kyung Kim, Joonsik Park, Jeong Eun Shin, Jungho Han, Ho Seon Eun
Summary: Low birth weight (LBW) infants have an increased risk of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), regardless of perinatal history.
SCIENTIFIC REPORTS
(2022)
Article
Pediatrics
Seung Han Shin, Seung Hyun Shin, Seh Hyun Kim, In Gyu Song, Young Hwa Jung, Ee-Kyung Kim, Han-Suk Kim
Summary: NIV-NAVA was more effective than NCPAP in preventing extubation failure in preterm infants.
JOURNAL OF PEDIATRICS
(2022)
Article
Pediatrics
Seung Hyun Shin, Jin A. Sohn, Ee-Kyung Kim, Seung Han Shin, Han-Suk Kim, Jin A. Lee
Summary: This retrospective cohort study aimed to identify factors associated with compliance to follow-up appointments among infants discharged from the neonatal intensive care unit (NICU). The study found that factors such as assisted reproductive technology usage, gestational age, birth weight, height, head circumference, and the number of siblings were associated with non-compliance. Additionally, Apgar scores, residential location, and certain complications were also found to be related to compliance. The study highlights the importance of these factors in determining follow-up compliance rates for infants.
PEDIATRICS AND NEONATOLOGY
(2022)
Article
Multidisciplinary Sciences
Hyun Iee Shin, Hyung-Ik Shin, Moon Suk Bang, Don-Kyu Kim, Seung Han Shin, Ee-Kyung Kim, Yoo-Jin Kim, Eun Sun Lee, Seul Gi Park, Hye Min Ji, Woo Hyung Lee
Summary: This study aimed to develop a quantitative assessment method for spontaneous movements in preterm infants using a deep learning algorithm. The complexity and similarity indices of joint angles and angular velocities were compared between infants with different Hammersmith Infant Neurological Examination (HINE) scores. The results showed that complexity indices of joint movements were positively correlated with HINE scores, suggesting their potential as indicators of developmental outcomes in preterm infants.
SCIENTIFIC REPORTS
(2022)
Article
Rehabilitation
Yoo Jinie Kim, Ee-Kyung Kim, Jung-Eun Cheon, Huijin Song, Moon Suk Bang, Hyung-Ik Shin, Seung Han Shin, Han-Suk Kim
Summary: In this study, brain imaging findings and neurodevelopmental outcomes of preterm infants diagnosed with cerebral palsy were analyzed. The study found that high-grade cerebellar hemorrhage and/or atrophy accounted for 25% of cerebellar injuries in patients with supratentorial lesions. Patients with cerebellar injury showed lower scores in various domains of neurodevelopmental assessment and had a higher proportion of patients below the cutoff value. Poor neurodevelopmental outcomes, other than motor function, were associated with cerebellar injury, indicating the importance of evaluating the cerebellum in predicting functional outcomes of cerebral palsy patients.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Multidisciplinary Sciences
Yoo Jinie Kim, Seung Han Shin, Hye Won Park, Ee-Kyung Kim, Han-Suk Kim
Summary: The aim of this meta-analysis was to determine the incidence and risk factors of early pulmonary hypertension (PHT) in preterm infants and evaluate its association with morbidities such as bronchopulmonary dysplasia (BPD), late PHT, and in-hospital mortality. The study found that early PHT is significantly associated with BPD, in-hospital mortality, and late PHT in preterm infants. Oligohydramnios and small-for-gestational-age are potential risk factors for early PHT in preterm infants.
SCIENTIFIC REPORTS
(2022)
Article
Clinical Neurology
Seh Hyun Kim, Seung Han Shin, Hyo Ju Yang, Seul Gi Park, Soo Yeon Lim, Young Hun Choi, Ee-Kyung Kim, Han-Suk Kim
Summary: Isolated cerebellar hemorrhage (CBH) is associated with abnormal motor development in preterm infants, and this study found it to be related to PCO2 fluctuation within 72 hours after birth. Isolated CBH accompanied by adverse neurodevelopmental outcomes is associated with a smaller ventral diencephalon and midbrain.
FRONTIERS IN NEUROLOGY
(2022)
Article
Pediatrics
Gayoung Lee, Juyoung Lee, Ga Won Jeon, Yong Hoon Jun
Summary: This study aimed to investigate the effects of a commercial thickened formula on oxygen saturation and heart rate stabilization during oral feeding in preterm infants. The results showed that TF feeding significantly reduces the frequency of desaturation and bradycardia during oral feeding, without causing diarrhea or electrolyte abnormalities.
CLINICAL AND EXPERIMENTAL PEDIATRICS
(2023)
Article
Pediatrics
Eun Sun Lee, Ee-Kyung Kim, Seung Han Shin, Young Hwa Jung, In-Gyu Song, Yoo-Jin Kim, Hyun Young Kim, Young-Hun Choi, Kyung Chul Moon, Bohyun Kim
Summary: This study aimed to evaluate the safety and benefits of mucous fistula refeeding (MFR) for growth and intestinal adaptation in preterm infants with enterostomies. The results showed that MFR significantly improved growth and intestinal adaptation in preterm infants, but further investigation is needed on infectious complications.
Article
Pediatrics
Jae Kyoon Hwang, Seung Han Shin, Ee-Kyung Kim, Seh Hyun Kim, Han-Suk Kim
Summary: This study evaluated the association between different definitions of bronchopulmonary dysplasia (BPD) and the occurrence of pulmonary hypertension (PHN) and long-term outcomes. The severity of BPD based on the 2019 NICHD definition was found to be associated with long-term outcomes and PHN at a postmenstrual age of 36 weeks in preterm infants.
FRONTIERS IN PEDIATRICS
(2023)