Article
Engineering, Multidisciplinary
Yanhe Liu, Jianbo Zhou, Wansi Fu, Bin Zhang, Feihu Chang, Pengfei Jiang
Summary: This study optimized diamond cutting tools for bamboo cutting using response surface methodology and found that feed speed has a significant impact on surface roughness. The best cutting combination can achieve better surface quality.
Article
Engineering, Electrical & Electronic
Zhiyong Wang, Qi Zhou, Fengyi Guo, Aixia Tang, Xili Wang, Xi Chen
Summary: This article studied the relationships between contact resistance and surface roughness characteristics in the pantograph-catenary system. Through numerous experiments, four characteristic parameters were proposed to describe surface roughness, and a new mathematical model considering rough surface characteristics was established and verified. The study is of great significance for further understanding the current conduction mechanism and evaluating the electrical contact performance in the pantograph-catenary system.
IEEE TRANSACTIONS ON TRANSPORTATION ELECTRIFICATION
(2022)
Article
Plant Sciences
Hui Lyu, Dusan Lazar
Summary: The transthylakoid membrane potential plays a crucial role in driving ATP synthesis and regulating photosynthesis under environmental stresses, with cation binding influencing the electric potentials adjustment. However, a comprehensive understanding of the impact of altered cationic binding on the membrane surface is still lacking.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Automation & Control Systems
Gopal Gote, Pushkar Kamble, Rajendra Hodgir, Yash Mittal, K. P. Karunakaran
Summary: This article investigates the surface roughness of expanded polystyrene foam machining and proposes a new theory for foam machining. A mathematical model is developed and validated, showing that bead removal contributes significantly more to surface roughness and that it can be improved by minimizing or avoiding bead removal.
INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY
(2022)
Article
Geochemistry & Geophysics
Jiandong Huang, Jia Zhang, Yuan Gao
Summary: This study aimed to predict rock joint shear strength using a combination of SVR and FA algorithms, showing that the FA algorithm effectively adjusts hyperparameters to optimize the SVR model for accurate prediction.
Article
Plant Sciences
Hui Lyu, Dusan Lazar
Summary: The light-induced transthylakoid membrane potential (Delta psi) plays a crucial role in ATP synthesis and in the acclimation of photosynthesis to changing light conditions. However, the mechanisms underlying ion fluxes and their impact on Delta psi regulation remain unclear.
PLANT PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Yajing Wang, Juan Li, Xiangdong Yang
Summary: This study established a new diffusion model of nutrient release, considering the mathematical relationship between the rate of nutrient release and the pore size. The model showed that the cumulative percentage of urea release was positively correlated with the membrane pore area and release time, while negatively correlated with the membrane thickness and particle mass. Experimental verification demonstrated that the model accurately reproduced the urea diffusion through membrane pores. Therefore, accurately controlling the pore size of CRF membrane based on this model is crucial for understanding the nutrient release of CRF.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2022)
Article
Chemistry, Medicinal
Johannes M. Nitsche, Gerald B. Kasting
Summary: This study analyzes and discusses experiments involving the binding of transient solutes to isolated keratin substrates, and their impact on the transient permeation of compounds applied topically through the human stratum corneum. The analysis expands upon a previous model by adding a second level of homogenization and provides insights into the effects of solute lipophilicity on binding kinetics. The findings have implications for understanding and quantifying the reservoir function of the stratum corneum.
JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Energy & Fuels
Peng Xu, Jin Meng, Jialiang Wang, Boming Yu, Shuxia Qiu
Summary: A novel pore-scale physical model for effective thermal conductivity (ETC) of multiscale unsaturated porous media is developed, which shows acceptable agreement with experimental results. It is found that increasing tortuosity leads to higher thermal resistance and reduced ETC, while rough surfaces and Knudsen effect enhance and reduce ETC, respectively.
Article
Geochemistry & Geophysics
Zheng Li, Jie Liu, Qian Shi, Kun Mao, Zhao Li, Hongyu Tang, Tianlong Wang
Summary: This research focused on studying the seepage characteristics of rough fractured rock masses and the distribution of flow fields for grouting to stop leakage. By developing a visual fracture seepage test device, the study visualized and analyzed the seepage characteristics of fractures under different stress paths, providing theoretical guidance for solving key scientific problems in grouting engineering.
Article
Geochemistry & Geophysics
Chen Wang, Lujie Zhou, Yujing Jiang, Xuepeng Zhang, Jiankang Liu
Summary: Appropriate understanding of the hydraulic characteristics of two-phase flow in rock fracture networks is crucial in many engineering applications. This study conducted a gas-water two-phase flow experiment in a smooth 3D model with intersecting fractures to investigate the two-phase flow characteristics. The results showed that the flow structures in intersecting fractures resembled stratified wavy flow in pipes. Considering the nonlinearity induced by inertial force and turbulence in intersecting fractures is important in two-phase flow, and the Martinelli-Lockhart model was found to be effective in this study.
Article
Materials Science, Multidisciplinary
Hu Qiao, Sibo Hu, Ying Xiang, Shanshan Liu, Li Zhang
Summary: Titanium alloys, as high-performance and difficult-to-machine materials, are increasingly used in high-end manufacturing industries such as aerospace. However, the choice of blade grinding parameters still relies on traditional trial and error methods, resulting in low processing efficiency and uncertain processing quality. In order to achieve high precision and low surface roughness, this paper proposes a theoretical prediction model for surface roughness during abrasive belt grinding of titanium alloy, and analyzes the influence of main process parameters through experiments. The developed model shows certain accuracy and reliability, providing guidance for high-precision prediction of surface roughness and having practical significance in engineering.
Article
Polymer Science
Shizhao Lu, Arthi Jayaraman
Summary: Nanorod roughness has a significant impact on aggregation, dispersion, and percolation of nanorods in polymer nanocomposites, hindering aggregation and promoting percolation with increasing roughness.
Article
Engineering, Chemical
Mohammed Abdul Azeem, Dahiru Umar Lawal, Hasan Al Abdulgader, Turki N. Baroud
Summary: In this study, a simple and cost-effective method for fabricating a superhydrophobic PVDF membrane was reported. The PVDF membrane with sandpaper-like texture was successfully developed using different casting substrates and a non-solvent induced phase separation process. The PDMS-based textured membrane showed excellent membrane distillation performance.
Article
Biochemistry & Molecular Biology
Denis Davydov, Elena Nosova, Sergey Loza, Aslan Achoh, Alexander Korzhov, Mikhail Sharafan, Stanislav Melnikov
Summary: The study demonstrates the potential of using a microheterogeneous model to estimate the transport numbers of counterions through ion-exchange membranes and calculating the open-circuit potential and power density of a reverse electrodialyzer. Different batches of Ralex membranes exhibit similar characteristics, while significant variations are found in the characteristics of MK-40 and MA-41 membranes in concentrated solutions.
Article
Engineering, Chemical
Randolph M. Pfeiffer, Annette L. Bunge
SEPARATION AND PURIFICATION TECHNOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Randolph M. Pfeiffer, Annette L. Bunge
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2020)
Review
Medicine, Legal
N. B. Hopf, C. Champmartin, L. Schenk, A. Berthet, L. Chedik, J. L. Du Plessis, A. Franken, F. Frasch, S. Gaskin, G. Johanson, A. Julander, G. Kasting, S. Kilo, F. Larese Filon, F. Marquet, K. Midander, E. Reale, A. L. Bunge
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2020)
Article
Pharmacology & Pharmacy
M. Hoppel, M. A. M. Tabosa, A. L. Bunge, M. B. Delgado-Charro, R. H. Guy
Summary: This study successfully tested the input rates of nicotine and lidocaine into healthy human skin using tape-stripping method, revealing differences in drug delivery between transdermal patches and creams. The experimental approach was validated and confirmed using in vitro diffusion cells with pig skin samples.
Article
Medicine, Research & Experimental
Andrea Pensado, Laura Hattam, K. A. Jane White, Anita McGrogan, Annette L. Bunge, Richard H. Guy, M. Begona Delgado-Charro
Summary: Prediction of skin absorption and local bioavailability from topical formulations remains a challenging task, with current research focusing on developing a physiologically based pharmacokinetic model to predict distribution and absorption of complex dermatological products. In vitro experimental results were consistent with commercial product performance and new skin sampling data demonstrated the input rate and drug delivery requirements of the Scopoderm patch.
MOLECULAR PHARMACEUTICS
(2021)
Article
Pharmacology & Pharmacy
M. Alice Maciel Tabosa, Sarah F. Cordery, K. A. Jane White, Annette L. Bunge, Richard H. Guy, M. Begona Delgado-Charro
Summary: The role of excipients in the partitioning and diffusion of drugs in the skin is crucial in the development of dermatological drug products. This study correlated the skin pharmacokinetics of diclofenac and the co-uptake of two key excipients, propylene glycol and butylene glycol, in human subjects. The results highlight the importance of considering the disposition of excipients in the optimization of drug delivery from topical formulations.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2022)
Article
Instruments & Instrumentation
Andrea Pensado, Anita McGrogan, K. A. Jane White, Annette L. Bunge, Richard H. Guy, M. Begona Delgado-Charro
Summary: Predicting the dermal bioavailability of topically delivered drugs is challenging. The study found that the uptake of betamethasone valerate into the stratum corneum was significantly higher at a dose of 5 mg/cm² compared to doses of 2 and 10 mg/cm². Skin blanching responses varied widely and were not sensitive to the dose of cream applied. The tape-stripping method was able to detect differences between applied doses, providing quantitative metrics for corticosteroid delivery.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2022)
Correction
Medicine, Research & Experimental
Andrea Pensado, Laura Hattam, K. A. Jane White, Anita McGrogan, Annette L. Bunge, Richard H. Guy, M. Begon Delgado-Charro
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Multidisciplinary
Sagar Shukla, Annette L. Bunge, Hazem E. Hassan, Audra L. Stinchcomb
Summary: The study evaluated the impact of different investigators in studies using a tape stripping protocol to minimize investigator variability. The results showed that the measurements of different investigators are reproducible within the limitations of measurement variability, which can be managed by increasing volunteer numbers.
PHARMACEUTICAL RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Parashara Shamaprasad, Timothy C. Moore, Donna Xia, Christopher R. Iacovella, Annette L. Bunge, Clare McCabe
Summary: Molecular dynamics simulations were used to study the structure of lipids in the stratum corneum layer of skin, revealing the role of cholesterol in membrane fluidity and thickness regulation. Combining coarse-grained force fields with atomistic simulations allowed for more accurate modeling of multilayer structures and better comparisons with experimental data.
Review
Biochemistry & Molecular Biology
Parashara Shamaprasad, Chloe O. Frame, Timothy C. Moore, Alexander Yang, Christopher R. Iacovella, Joke A. Bouwstra, Annette L. Bunge, Clare McCabe
Summary: The skin's outermost layer, the stratum corneum (SC), plays a crucial role in acting as a barrier against water and chemicals. The lipid composition of the SC, consisting of ceramides, cholesterol, and free fatty acids, contributes to its protective function. Molecular simulation has emerged as a valuable tool for studying SC lipid systems and this review aims to provide insights and guidance for both experimentalists and simulation experts in the field. It critically examines the methodology and results of atomistic and coarse-grained models.
PROGRESS IN LIPID RESEARCH
(2022)
Article
Medicine, Research & Experimental
M. Alice Maciel Tabosa, Pauline Vitry, Panagiota Zarmpi, Annette L. Bunge, Natalie A. Belsey, Dimitrios Tsikritsis, Timothy J. Woodman, K. A. Jane White, M. Begona Delgado-Charro, Richard H. Guy
Summary: The evaluation of drug bioavailability in the skin requires quantitative and non-invasive experimental tools. In this study, infrared and Raman spectroscopies were used to assess the uptake of a chemical into the stratum corneum. Experiments on excised porcine skin showed good correlations between spectroscopic results and chemical quantification using the tape-stripping method. The spectroscopic approach can potentially be used to investigate chemical disposition deeper in the skin.
MOLECULAR PHARMACEUTICS
(2023)
Article
Medicine, Research & Experimental
Panagiota Zarmpi, M. Alice Maciel Tabosa, Pauline Vitry, Annette L. Bunge, Natalie A. Belsey, Dimitrios Tsikritsis, Timothy J. Woodman, M. Begona Delgado-Charro, Richard H. Guy
Summary: Confocal Raman spectroscopy is a promising tool for quantifying drug uptake and clearance in the skin, providing valuable insights into local bioavailability. This research confirmed that Raman signals can be used to correct for signal attenuation and detect drug disposition, as well as distinguish between different formulations.
MOLECULAR PHARMACEUTICS
(2023)
Correction
Medicine, Research & Experimental
Andrea Pensado, Laura Hattam, K. A. . Jane White, Anita McGrogan, Annette L. Bunge, Richard H. Guy, M. Begona Delgado-Charro
MOLECULAR PHARMACEUTICS
(2022)
Article
Instruments & Instrumentation
Maria Alice Maciel Tabosa, Magdalena Hoppel, Annette L. Bunge, Richard H. Guy, M. Begona Delgado-Charro
Summary: The study shows that drug clearance from the difficult-to-access compartment in the skin can be inferred from systemic pharmacokinetic data, and is closely related to key physical chemical properties of the drug. A multiple regression analysis was used to determine this relationship and demonstrated that the model predictions correlated well with in vitro skin experiments.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2021)
Article
Engineering, Chemical
Jiawei Hou, Shixuan Guo, Nigel Graham, Wenzheng Yu, Kening Sun, Ting Liu
Summary: A novel 2D composite membrane based on r-HGO and MXene materials was developed, demonstrating exceptional performance for water treatment in terms of permeability, pollutant rejection, and physical stability. The optimization of preparation conditions and material proportions can result in high water flux and efficient removal of pollutants.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Retraction
Engineering, Chemical
Chang Liu, Jinghong Liu, Liang Zhu, Shanfu Tang, Huixin Xiong
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Rui Gao, Caihong Liu, Andreia F. Faria, Qiang He, Chun Yang, Jun Ma
Summary: A novel copolymer architecture has been developed to address biofouling concerns in thin-film composite (TFC) membranes by integrating anti-fouling, bactericidal, and fouling-release functions. The multifunctional membrane demonstrates promising anti-adhesive properties, self-cleaning ability, and high flux recovery rate.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Alexander T. Bridge, Noah P. Wamble, Matthew S. Santoso, Joan F. Brennecke, Benny D. Freeman
Summary: This study demonstrates the reproducible preparation of high-flux defect-free asymmetric gas separation membranes using Cyrene(TM) as a majority dope formulation component. By adjusting the volume ratios of Cyrene(TM) and THF, as well as the concentrations of Matrimid(R) and the dry step time, optimal membrane performance is achieved.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Alessandra Imbrogno, Han Ya Lin, Babak Minofar, Andrea Iris Schaefer
Summary: In this study, a composite nanofiber membrane containing cross-linked beta-cyclodextrin-epichlorohydrin was prepared and evaluated for the removal of steroid hormones. The results showed that the membrane had high adsorption capacity and the ability to form a specific inclusion complex interaction with the hormones, indicating its potential application in hormone removal.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Bora Shin, Jaewon Shin, Yanuar Chandra Wirasembada, Ki Young Park, Jinwoo Cho
Summary: This study develops a mathematical model to estimate the initial flux of volatile fatty acids in the direct contact membrane distillation process. It identifies the parameters affecting the flux and their relationship with pH.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Yi-Jui Yeh, Jr Rong Liou, Wei Lin, Kuo-Lun Tung, Wei-Hung Chiang
Summary: This study demonstrates an effective plasma engineering method to create nitrogen-doped graphene quantum dot (NGQD)-inorganic nanocomposites for tunable molecular separation. The composite materials show high separation efficiency and controllable nanopore structures, making them potentially valuable for various applications.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Horacio Lopez-Marques, Kristofer L. Gleason, Manuel Aguilar-Vega, Rita Sulub-Sulub, J. Ehren Eichler, Hyeonji Oh, C. Buddie Mullins, Benny D. Freeman, Manish Kumar
Summary: In this study, water transport properties in Carbon Molecular Sieve (CMS) membranes were investigated. It was found that membranes synthesized at different pyrolysis temperatures exhibited varying water permeabilities. Compared to other polymeric materials, CMS membranes showed high water permeability, indicating potential for dehydration applications.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Dmitry A. Alentiev, Roman Yu. Nikiforov, Marina A. Rudakova, Danil P. Zarezin, Maxim A. Topchiy, Andrey F. Asachenko, Nikolay A. Belov, Maxim Bermeshev
Summary: A series of new norbornene-type monomers containing linear and branched substituents were synthesized, and robust thin membranes were prepared by vinyl-addition polymerization. Gas separation performance for the synthesized polymers was evaluated, and the structure of substituent side chains was found to significantly affect gas permeability and CO2 facilitated transport.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Lei Yan, Qi Zhang, Ze Zhang, Gui-Jie Li, Yi Jin, Xin-Lin Zhang, Yan-Yun Sun
Summary: In this study, a continuous, stable and fast ion transport channel was established through in-situ guided cross-linking of zinc alginate hydrogels on a porous membrane, overcoming the negative pore effect and effectively inhibiting the dendrite growth of zinc anodes and interfacial side reactions.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Yuqing Zhang, Ailing Zhang, Huiyang He, Yuting Fan, Yongjiang Li, Song Wang, Sanxi Li
Summary: The Langmuir-Blodgett self-assembly process is used to create an ordered SPEEK membrane, which enhances the proton conductivity by three times compared to conventional solution casting method.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Hasan Ismaeel, David Gibson, Eleonora Ricci, Maria Grazia De Angelis
Summary: In this study, a machine learning-based group contribution method (ML-GC) was developed to predict pure polymer parameters and successfully applied to predict gas solubility and gas solubility isotherms in glassy polymeric membranes. The model showed satisfactory performance on a small dataset, but has the potential to provide more accurate predictions for a wider range of polymers as more data becomes available.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Yi Ji, Yu Sun, Huilin Li, Qiang Fu, Yan Zhang
Summary: Previous studies have shown that vibration- or rotation-based techniques can effectively mitigate fouling during membrane filtration. However, it is difficult to incorporate these techniques with spiral wound modules (SWMs) widely used in water and wastewater treatment. This study developed a prototype membrane system to accommodate angular vibrations with a modified SWM, and experimental results showed that applying angular vibrations can effectively control algal fouling in an SWM with lower energy consumption compared to traditional methods.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Lakshmeesha Upadhayaya, Abaynesh Yihdego Gebreyohannes, Muhammad Wakil Shahzad, Usman T. Syed, Sandra L. Aristizabal, Radoslaw Gorecki, Suzana P. Nunes
Summary: Increasing temperatures worldwide pose a significant health risk, exacerbated by high humidity. Conventional air conditioners contribute heavily to carbon dioxide emissions, with dehumidification being a major factor. Membrane-based dehumidification system offers energy efficiency and non-toxic water vapor removal. This study demonstrates a membrane dehumidification system with polymeric hollow fibers coated with a green polyphenol coating, showing remarkable water vapor transport rate and selectivity. Long-term testing reveals minimal decline in vapor transport and a 4-5 times higher coefficient of performance (COP) compared to conventional dehumidifiers, making it a highly competitive, energy-saving device with reduced emissions and a smaller footprint.
JOURNAL OF MEMBRANE SCIENCE
(2024)
Article
Engineering, Chemical
Zhengzhong Zhou, Xue Zhu, Yi Yuan, Shaoqiang Wang, Xiaoshan Meng, Taoli Huhe, Qian Wang
Summary: In this study, lignin, a biomass material, was chemically modified and utilized in the interfacial polymerization process to improve the performance of nanofiltration membranes. The modified membranes showed enhanced hydrophilicity and anti-fouling properties, and the optimization of membrane pore size increased permeability. The study also demonstrated the potential application of the membranes in biogas slurry valorization.
JOURNAL OF MEMBRANE SCIENCE
(2024)