Increased soluble phagocytic receptors sMer, sTyro3 and sAxl and reduced phagocytosis in Juvenile-onset Systemic Lupus Erythematosus

Major infections in a cohort of 120 patients with juvenile-onset systemic lupus erythematosus

(2013) Patrícia Costa-Reis et al.   CLINICAL IMMUNOLOGY

Th1/Th2 cytokine profile in childhood-onset systemic lupus erythematosus

(2013) Mariana Postal et al.   CYTOKINE

Prolonged Apoptotic Cell Accumulation in Germinal Centers of Mer-Deficient Mice Causes Elevated B Cell and CD4+ Th Cell Responses Leading to Autoantibody Production

(2013) T. N. Khan et al.   JOURNAL OF IMMUNOLOGY

Impaired phagocytosis and susceptibility to infection in pediatric-onset systemic lupus erythematosus

(2013) S-A Wu et al.   LUPUS

Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity

(2013) Pedro Recarte-Pelz et al.   ARTHRITIS RESEARCH & THERAPY

Disease activity, severity, and damage in the UK juvenile-onset systemic lupus erythematosus cohort

(2012) Louise Watson et al.   ARTHRITIS AND RHEUMATISM

Efficient Clearance of Early Apoptotic Cells by Human Macrophages Requires M2c Polarization and MerTK Induction

(2012) G. Zizzo et al.   JOURNAL OF IMMUNOLOGY

Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-κB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury

(2012) Ye-Ji Lee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Preventing cleavage of Mer promotes efferocytosis and suppresses acute lung injury in bleomycin treated mice

(2012) Ye-Ji Lee et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genes, epigenetic regulation and environmental factors: Which is the most relevant in developing autoimmune diseases?

(2011) Karen H. Costenbader et al.   AUTOIMMUNITY REVIEWS

Shedding of the Mer Tyrosine Kinase Receptor Is Mediated by ADAM17 Protein through a Pathway Involving Reactive Oxygen Species, Protein Kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)

(2011) Edward Thorp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines

(2011) A. Kuznik et al.   JOURNAL OF IMMUNOLOGY

The glucocorticoid dexamethasone programs human dendritic cells for enhanced phagocytosis of apoptotic neutrophils and inflammatory response

(2011) Judit Hodrea et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The innate immune system and the clearance of apoptotic cells

(2011) Andrew Devitt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cellular localization of nuclear antigen during neutrophil apoptosis: mechanism for autoantigen exposure?

(2011) A Midgley et al.   LUPUS

Differentiation and Glucocorticoid Regulated Apopto-Phagocytic Gene Expression Patterns in Human Macrophages. Role of Mertk in Enhanced Phagocytosis

(2011) Gábor Zahuczky et al.   PLoS One

Increased plasma levels of the soluble Mer tyrosine kinase receptor in systemic lupus erythematosus relate to disease activity and nephritis

(2011) Jun Wu et al.   ARTHRITIS RESEARCH & THERAPY

TAM receptor signaling and autoimmune disease

(2010) Carla V Rothlin et al.   CURRENT OPINION IN IMMUNOLOGY

Lipopolysaccharide inhibits macrophage phagocytosis of apoptotic neutrophils by regulating the production of tumour necrosis factor α and growth arrest-specific gene 6

(2010) Xueying Feng et al.   IMMUNOLOGY

TNF-α, IL-6, and IL-1 expression is inhibited by GAS6 in monocytes/macrophages

(2010) Federica Alciato et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The role of neutrophil apoptosis in juvenile-onset systemic lupus erythematosus

(2009) Angela Midgley et al.   ARTHRITIS AND RHEUMATISM

TAM receptors are dispensable in the phagocytosis and killing of bacteria

(2009) By Julie C. Williams et al.   CELLULAR IMMUNOLOGY

Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages

(2009) A. McColl et al.   JOURNAL OF IMMUNOLOGY

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus

(2008) I E A Hoffman et al.   ANNALS OF THE RHEUMATIC DISEASES

Difference in disease features between childhood-onset and adult-onset systemic lupus erythematosus

(2008) Hermine I. Brunner et al.   ARTHRITIS AND RHEUMATISM