A novel surfactant protein C L55F mutation associated with interstitial lung disease alters subcellular localization of proSP-C in A549 cells

A non-BRICHOS SFTPC mutant (SP-CI73T) linked to interstitial lung disease promotes a late block in macroautophagy disrupting cellular proteostasis and mitophagy

(2015) Arie Hawkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Genetic testing in children with surfactant dysfunction

(2013) S. Turcu et al.   ARCHIVES OF DISEASE IN CHILDHOOD

SFTPCmutations cause SP-C degradation and aggregate formation without increasing ER stress

(2013) Tobias Thurm et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

High-resolution structure of a BRICHOS domain and its implications for anti-amyloid chaperone activity on lung surfactant protein C

(2012) H. Willander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The surfactant protein C mutation A116D alters cellular processing, stress tolerance, surfactant lipid composition, and immune cell activation

(2012) Ralf Zarbock et al.   BMC Pulmonary Medicine

Delayed Chest Closure Assessed by Transesophageal Echocardiogram in Single-Lobe Lung Transplantation

(2011) Fengshi Chen et al.   ANNALS OF THORACIC SURGERY

Multiple ways to die: Delineation of the unfolded protein response and apoptosis induced by Surfactant Protein C BRICHOS mutants

(2011) Jean Ann Maguire et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Nonaggregating Surfactant Protein C Mutant Is Misdirected to Early Endosomes and Disrupts Phospholipid Recycling

(2011) Michael F. Beers et al.   TRAFFIC

A non-BRICHOS surfactant protein c mutation disrupts epithelial cell function and intercellular signaling

(2010) Markus Woischnik et al.   BMC CELL BIOLOGY

New surfactant protein C gene mutations associated with diffuse lung disease

(2009) L Guillot et al.   JOURNAL OF MEDICAL GENETICS

Familial interstitial disease with I73T mutation: A mid- and long-term study

(2009) Rola Abou Taam et al.   PEDIATRIC PULMONOLOGY

Two novel mutations in surfactant protein-C, lung function and obstructive lung disease

(2009) Marie Bækvad-Hansen et al.   RESPIRATORY MEDICINE

Mutations linked to interstitial lung disease can abrogate anti-amyloid function of prosurfactant protein C

(2008) Charlotte Nerelius et al.   BIOCHEMICAL JOURNAL