Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

标题
Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities
作者
关键词
-
出版物
JOURNAL OF MEDICINAL CHEMISTRY
Volume 57, Issue 20, Pages 8657-8663
出版商
American Chemical Society (ACS)
发表日期
2014-08-29
DOI
10.1021/jm5011258

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