Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis

标题
Acyl Guanidine Inhibitors of β-Secretase (BACE-1): Optimization of a Micromolar Hit to a Nanomolar Lead via Iterative Solid- and Solution-Phase Library Synthesis
作者
关键词
-
出版物
JOURNAL OF MEDICINAL CHEMISTRY
Volume 55, Issue 21, Pages 9208-9223
出版商
American Chemical Society (ACS)
发表日期
2012-09-05
DOI
10.1021/jm300931y

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