Article
Cell Biology
Timothy Kudinha, Fanrong Kong
Summary: The study found that the papGII gene is more closely associated with other VF genes compared to the papGIII gene in E. coli causing urinary tract infections, explaining the abundance of these genes in pyelonephritis and cystitis isolates.
JOURNAL OF BIOMEDICAL SCIENCE
(2022)
Article
Microbiology
Ulrik Engelsoy, Maria A. A. Svensson, Isak Demirel
Summary: In this study, it was found that estradiol exposure increased UPEC growth and biofilm formation, as well as colonization and invasion of bladder epithelial cells. Additionally, estradiol altered the expression of genes associated with iron acquisition system and metabolic pathways in UPEC.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Lorina Badger-Emeka, Naheed Kausar, Edric Estrella, Glenda Belgira Angeles
Summary: Uropathogenic Escherichia coli is the most common cause of urinary tract infections, and it has multidrug resistance and extended-spectrum beta-lactamase (ESBL) characteristics. This study investigated the antimicrobial susceptibility patterns and associated virulence determinants of UPEC isolates and found that phylogroups B2 and D carried the most virulence genes.
Article
Microbiology
Juraj Bosak, Darina Kohoutova, Matej Hrala, Jitka Krenova, Paula Moravkova, Stanislav Rejchrt, Jan Bures, David Smajs
Summary: This study aimed to characterize mucosal E. coli isolates from patients with colorectal neoplasia and healthy controls. Results showed that E. coli isolated from neoplasia patients carried a higher prevalence of virulence determinants compared to the control group. These findings suggest that E. coli strains isolated from patients with colorectal neoplasia possess several virulence factors, which could contribute to the development of neoplastic processes.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Ningning Song, Henri De Greve, Quanjun Wang, Jean-Pierre Hernalsteens, Zhaoli Li
Summary: This study suggests that the parB gene of the endogenous plasmid pUTI89 in UPEC strains plays a crucial role in biofilm formation and gene expression, and can affect the virulence of the pathogen by influencing bacterial colonization in the bladder and kidneys.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2022)
Article
Microbiology
Arwen E. Frick-Cheng, Anna Sintsova, Sara N. Smith, Ali Pirani, Evan S. Snitkin, Harry L. T. Mobley
Summary: More than half of women will experience a urinary tract infection (UTI), with uropathogenic Escherichia coli (UPEC) causing the majority of cases. Iron acquisition systems play a crucial role in UPEC pathogenesis, and this study reveals the importance of the ferric citrate uptake system as an alternative iron source when other siderophores are limited. Understanding these iron acquisition mechanisms is important for developing new strategies to combat UTI.
Article
Agriculture, Dairy & Animal Science
Toshiyuki Murase, Hiroichi Ozaki
Summary: This study showed that the prevalence of phylogroup F was higher in colibacillosis-related isolates compared to healthy chicken-related isolates, while phylogroups A and B1 were more commonly found in the latter. APEC strains with virulence-associated genes were more prevalent in colibacillosis-related isolates, indicating that phylogroup F can predict colibacillosis in E. coli strains.
Review
Immunology
Mehrdad Halaji, Amirhossein Fayyazi, Mehdi Rajabnia, Donya Zare, Abazar Pournajaf, Reza Ranjbar
Summary: The phylogenetic classification of Escherichia coli isolates in Iran, especially uropathogenic strains, was investigated in this study. The prevalence of different phylogroups, antibiotic susceptibility patterns, and virulence genes were analyzed through a systematic review and meta-analysis. The results showed that phylogroups B-2 and D were the most predominant groups in UPEC isolates from different regions of Iran. Certain phylogroups exhibited higher antibiotic resistance. Comprehensive infection control measures should be implemented to control the spread of virulent phylogroups B-2 and D, and strategies for monitoring antibiotic therapy should be developed.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Infectious Diseases
Seyedeh Elham Rezatofighi, Mahsa Mirzarazi, Mansour Salehi
Summary: UTI, caused by UPEC, is a common bacterial infectious disease with significant morbidity. The genetic structure and virulence factors of UPEC vary between clinical and commensal isolates, with B2 and D phylogenetic groups strongly associated with UPEC. Understanding the epidemiology and characteristics of UPEC isolates in different regions is crucial for controlling UTI. Interfering with intestinal colonization, particularly in pathogenic clonal lineages like B2, may help reduce the burden of UTI.
BMC INFECTIOUS DISEASES
(2021)
Article
Biochemistry & Molecular Biology
Xinyang Zhang, Dongyan Huang, Zihui Zhao, Xuwang Cai, Wentong Cai, Ganwu Li
Summary: Research has found that the biosynthesis of bis-molybdopterin guanine dinucleotide (bis-MGD) plays a crucial role in modulating the expression of hemolysin in uropathogenic Escherichia coli (UPEC), especially under anaerobic conditions. Further studies revealed that NtrC acts as a direct repressor of c3566-c3568-hlyCABD expression, and intact bis-MGD biosynthesis downregulates ntrC expression, partially explaining the positive role of bis-MGD in modulating hemolysin expression.
MOLECULAR MICROBIOLOGY
(2021)
Article
Infectious Diseases
Sofia Alejandra Fonseca-Martinez, Ruth Arali Martinez-Vega, Ana Elvira Farfan-Garcia, Clara Isabel Gonzalez Rugeles, Libeth Yajaira Criado-Guerrero
Summary: The aim of this study was to determine the association of nine UPEC virulence genes with UTI severity and antibiotic resistance. The results showed that these genes were not associated with UTI severity, but three of them were associated with resistance to at least one antibiotic family. The significance of this study lies in the continued research on the bacterial genetic characteristics that cause the generation of pathogenic and multidrug-resistant phenotypes of UPEC strains.
INFECTION AND DRUG RESISTANCE
(2023)
Article
Immunology
Shujie Li, Yu Pang, Si Zhang, Qing Li, Qian Wang, Lei Wang, Lu Feng
Summary: This study provides the first comprehensive analysis of the transcriptome profile of UPEC during its intra-BECs life, revealing a new virulence-associated gene and its regulatory mechanism.
MICROBIAL PATHOGENESIS
(2021)
Article
Microbiology
Julia Ittensohn, Jacqueline Hemberger, Hannah Griffiths, Maren Keller, Simone Albrecht, Thomas Miethke
Summary: The study demonstrates that the uropathogenic Escherichia coli strain CFT073 causes kidney abscesses in mice through the TcpC gene, which is present in around 40% of E. coli isolates of pyelonephritis patients. TcpC impairs host immune response by affecting the TLR signaling chain and NLRP3 inflammasome.
Article
Agriculture, Dairy & Animal Science
Fabrizio Bertelloni, Giulia Cagnoli, Fabrizio Biagini, Alessandro Poli, Carlo Bibbiani, Valentina Virginia Ebani
Summary: Escherichia coli is a commensal of the human and animal intestinal tract, but certain pathogenic strains can cause severe infections. Wildlife may carry and transmit these pathogenic strains, posing a potential source of infection for humans and domestic animals. Red foxes, in particular, seem to play a role in the epidemiology of these infections, especially when they invade human settlements in rural and urban areas.
Article
Biotechnology & Applied Microbiology
Mohammed Allami, Masoumeh Bahreini, Mohammad Reza Sharifmoghadam
Summary: This study investigated the virulence factors, antibiotic resistance, and phylogenetic groups of UPEC strains isolated from UTI patients in southern Iraq. The majority of isolates belonged to phylogenetic groups B2 and C, and the most prevalent virulence factor was fimH. There was a direct relationship between virulence factors, gene diversity, phylogenetic background, and antimicrobial resistance in the UPEC isolates.
JOURNAL OF APPLIED GENETICS
(2022)
Article
Green & Sustainable Science & Technology
Joanne Millar, Wayne Robinson, Lee Baumgartner, Khampheng Homsombath, Malavanh Chittavong, Thonglome Phommavong, Douangkham Singhanouvong
ENVIRONMENT DEVELOPMENT AND SUSTAINABILITY
(2019)
Article
Agriculture, Multidisciplinary
Matthew W. Herring, Wayne Robinson, Kerstin K. Zander, Stephen T. Garnett
AGRICULTURE ECOSYSTEMS & ENVIRONMENT
(2019)
Article
Environmental Sciences
Lee J. Baumgartner, Craig Boys, Tim Marsden, Jarrod McPherson, Nathan Ning, Oudom Phonekhampheng, Wayne Robinson, Douangkham Singhanouvong, Ivor G. Stuart, Garry Thorncraft
Article
Agronomy
Jane E. Kelly, Allison J. Chambers, Paul A. Weston, William B. Brown, Wayne A. Robinson, John C. Broster, Leslie A. Weston
Article
Entomology
Z. Palfi, W. Robinson, P. G. Spooner
Article
Environmental Sciences
Katherine E. Doyle, Nathan Ning, Luiz G. M. Silva, Eduardo M. Brambilla, Craig A. Boys, Z. Daniel Deng, Tao Fu, Jan A. du Preez, Wayne Robinson, Lee J. Baumgartner
FRONTIERS IN ENVIRONMENTAL SCIENCE
(2020)
Article
Agriculture, Multidisciplinary
Matthew W. Herring, Wayne A. Robinson, Kerstin K. Zander, Stephen T. Garnett
Summary: Many species have adapted to traditional agricultural environments, but as production systems intensify, their adaptation is being limited. Water-saving irrigation methods in rice fields have compromised the habitat value of the globally endangered Australasian Bittern, as the ponding period is too short for successful breeding.
AGRICULTURE ECOSYSTEMS & ENVIRONMENT
(2021)
Article
Biodiversity Conservation
Maria Joao Feio, Robert M. Hughes, Sonia R. Q. Serra, Susan J. Nichols, Ben J. Kefford, Mark Lintermans, Wayne Robinson, Oghenekaro N. Odume, Marcos Callisto, Diego R. Macedo, Jon S. Harding, Adam G. Yates, Wendy Monk, Keigo Nakamura, Terutaka Mori, Masanao Sueyoshi, Norman Mercado-Silva, Kai Chen, Min Jeong Baek, Yeon Jae Bae, Ram Devi Tachamo-Shah, Deep Narayan Shah, Ian Campbell, Nabor Moya, Francis O. Arimoro, Unique N. Keke, Renato T. Martins, Carlos B. M. Alves, Paulo S. Pompeu, Subodh Sharma
Summary: This study evaluated the biological condition of rivers globally and provided recommendations for river ecosystem conservation. The results showed that good biological conditions were associated with good water quality and increased forested areas, while severely impaired conditions were associated with higher human development index scores, poorer water quality, and fewer protected freshwater areas. The study highlights the importance of implementing statutory bioassessment programs in Asian, African, and South American countries.
GLOBAL CHANGE BIOLOGY
(2023)
Article
Fisheries
John Conallin, Nyi Nyi Tun, Aye Myint Swe, Lee J. Baumgartner, Zau Lunn, Martin Mallen-Cooper, Tim Marsden, Nathan Ning, Wayne Robinson, Lalantha Senevirathna, Peter Thew
Summary: The construction of dams and other river infrastructures is threatening the population of migratory fish species by reducing river-floodplain connectivity. Fishways are important tools for restoring river connectivity for these fishes, but their effectiveness is often limited by a lack of biological information on the target species, especially in developing countries. This study aimed to inform the design of a vertical-slot fishway for migratory fishes in Myanmar. The results showed that the ability of fish to pass through the flume was influenced by hydraulic conditions and fish size. Obtaining baseline biological information on the target species is crucial for optimizing the effectiveness of planned fishways.
FISHERIES RESEARCH
(2023)
Article
Environmental Sciences
Dana Lee, Jackman C. Eschenroeder, Lee J. Baumgartner, Bunyeth Chan, Sudeep Chandra, Seila Chea, Sothearoth Chea, Chheana Chhut, Elizabeth Everest, Radong Hom, Kong Heng, Stefan Lovgren, Sinsamout Ounboundisane, Wayne Robinson, Lykheang Seat, Sobot Soth, Zeb S. Hogan
Summary: The Mekong River supports a diverse range of fish species and the livelihoods of millions of people. However, little is known about the spatial dynamics and population status of many Mekong fish species, especially megafishes. This study presents initial findings from acoustic telemetry monitoring, which provide important insights into the potential impacts that hydropower dams would have on ecologically and economically important fish species.
Article
Environmental Sciences
An V. Vu, Lee J. Baumgartner, Martin Mallen-Cooper, Julia A. Howitt, Wayne A. Robinson, Nam So, Ian G. Cowx
Summary: Diadromous fish migration is vulnerable to river infrastructural development, and the Lower Mekong Basin is experiencing a boom in river development. However, there is limited information on diadromous fish migration in the basin. This study found that diadromy is more common in the basin than previously assumed, and these fish species contribute to the total catch and include economically valuable endemic species.
JOURNAL OF ECOHYDRAULICS
(2023)
Article
Infectious Diseases
Dylan John Astley, Labolina Spang, Fatemeh Parnian, Tara Vollmerhausen, Huseyin Kilic, Mehmet Hora, Aycan Gundogdu, Mohammad Katouli
Summary: This study investigated the clonal composition and virulence characteristics of UPEC isolated from Australian and Turkish UTI patients. Australian UPEC strains showed higher clonal diversity and higher virulence potential compared to Turkish strains, carrying more genes associated with adhesion, iron acquisition, and capsule biosynthesis.
Article
Biodiversity Conservation
Katherine E. Doyle, Nathan Ning, Luiz G. M. Silva, Eduardo M. Brambilla, Z. Daniel Deng, Tao Fu, Craig Boys, Wayne Robinson, Jan A. du Preez, Lee J. Baumgartner
Summary: The global prevalence of pumped-storage hydropower (PSH) is expected to grow exponentially as countries transition to renewable energy sources. Little is known about the impact of PSH on aquatic biota compared to conventional hydropower. This study simulated the passage of European perch through a PSH facility and found that the species could survive the stressors expected within the facility, although survival varied among different life stages.
CONSERVATION PHYSIOLOGY
(2022)
Review
Geosciences, Multidisciplinary
John Conallin, Nathan Ning, Jennifer Bond, Nicholas Pawsey, Lee J. Baumgartner, Dwi Atminarso, Hannah McPherson, Wayne Robinson, Garry Thorncraft
Summary: The MOTA framework addresses the gap in proactive approaches for analysing implementation issues during the planning stage of water resource plans and policies. By focusing on the motivations and abilities of stakeholders, it has been successful in identifying strategies needed for effective implementation in various institutional implementation and social adoptability contexts. The addition of complementary applications and more nuanced scoring approaches could further enhance the MOTA framework's potential for optimizing implementation success in water planning and policymaking contexts.
HYDROLOGY AND EARTH SYSTEM SCIENCES
(2022)
Article
Fisheries
Jamin P. Forbes, Charles R. Todd, Lee J. Baumgartner, Robyn J. Watts, Wayne A. Robinson, Aldo S. Steffe, Jeff J. Murphy, Martin W. Asmus, Jason D. Thiem
MARINE AND FRESHWATER RESEARCH
(2020)