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Synthesis of mesoporous structured hydroxyapatite particles using yeast cells as the template

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SPRINGER
DOI: 10.1007/s10856-009-3865-3

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  1. National Key Basic Research 973 Program of China [2005CB623902]
  2. National Natural Science Foundation of China [50572029]
  3. Natural Science Foundation Team Project of Guangdong [04205786]

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In this study, hydroxyapatite (HAp) particles with mesoporous structure have been synthesized from calcium hydroxide and di-ammonium hydrogen phosphate using yeast cells as the template. The characterization methods such as X-ray diffraction (XRD), Fourier transform infrared spectrograph (FTIR), N-2 adsorption-desorption isotherms (NADI), transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) were used for determination of the particles structure (particle size, structural evolution and morphology). The results show that HAp particles with mesoporous structure could be produced. The size of HAp particles was approximately hundreds of nanometer. The pore width of HAp particles was in the range of 2.0-40 nm and the maximum centered around 4.5 nm.

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