Article
Chemistry, Multidisciplinary
Jae Hyung Kim, Dongyup Shin, Jinjong Kim, June Sung Lim, Vinod K. Paidi, Tae Joo Shin, Hu Young Jeong, Kug-Seung Lee, Hyungjun Kim, Sang Hoon Joo
Summary: Reversible control of the coordination structure in atomically dispersed electrocatalysts can be achieved via ligand exchange reactions to modulate their reactivity for oxygen reduction reaction. The CO-ligated Rh catalyst shows higher ORR activity, while the NHx-ligated catalyst exhibits higher H2O2 selectivity. This reversible ligand exchange strategy is applicable to Ir- and Pt-based catalysts as well.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Chemistry, Multidisciplinary
Meihui Yi, Weiyi Tan, Jiaqi Guo, Bing Xu
Summary: Enzymatic noncovalent synthesis allows for the control of multimolecular crowding in cells, offering opportunities for modulating cellular functions and various biomedical applications.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Nan Yan, Nan Xia, Zhikun Wu
Summary: Ligand exchange reactions in metal nanoparticles, especially metal nanoclusters, have attracted significant interest for tailoring their properties. The intrinsic stability plays a key role in determining the direction of ligand exchange, as revealed by single crystal X-ray crystallography. The reversal of surface ligand configuration after exchange provides evidence for a unimolecular nucleophilic substitution mechanism.
Article
Nanoscience & Nanotechnology
Niki Karouta, Yannis V. Simos, Georgia Basina, Konstantinos Spyrou, Mohammed Subrati, Alexandra V. Chatzikonstantinou, Mohamed Amen Hammami, Vasileios Tzitzios, Saeed M. Alhassan, Yasser Al Wahedi, Alexios P. Douvalis, George C. Hadjipanayis, Konstantinos Tsamis, Evangelia Dounousi, Georgios S. Markopoulos, Sofia Bellou, Vasilios Georgakilas, Dimitrios Peschos, Zili Sideratou, Haralambos Stamatis, Dimitrios P. Gournis, Emmanuel P. Giannelis
Summary: This study presents a new strategy for designing highly hydrophilic and functional nanoparticles through a haircut reaction. The as-synthesized SPIONs, modified by oleylamine molecules, exhibit high hydrophilicity, dispersibility in water, and functionality. These functional nanoparticles show selective cytotoxic effects against cancer cells and have the potential to be developed into a new generation of nanomaterials for biomedical applications.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Leon Escomel, Daniel F. Abbott, Victor Mougel, Laurent Veyre, Chloe Thieuleux, Clement Camp
Summary: Iridium-aluminium nanoparticles grafted onto silica show enhanced catalytic performances in methane H/D exchange, compared to monometallic iridium nanoparticles. The catalyst exhibits high TON values and remains active after exposure to air, indicating good robustness.
CHEMICAL COMMUNICATIONS
(2022)
Review
Biochemistry & Molecular Biology
Sagrario Yadira Gutierrez de la Rosa, Ramiro Muniz Diaz, Paola Trinidad Villalobos Gutierrez, Rita Patakfalvi, Oscar Gutierrez Coronado
Summary: Functionalized platinum nanoparticles have attracted considerable research interest as therapeutic agents due to their properties and applications. By functionalizing the nanoparticle surfaces, selectivity can be increased and the side effects of conventional drugs can be reduced. With the development of nanotechnology in the biomedical field, functionalized platinum nanoparticles have been utilized for the diagnosis and treatment of diseases such as cancer and infections. This review discusses the physical, chemical, and biological methods of obtaining platinum nanoparticles and explores the advantages and disadvantages of their synthesis. Furthermore, it explores the applications in the biomedical field that can be achieved by functionalizing the nanoparticle surfaces with different bioactive molecules, including antibodies, biodegradable polymers, and biomolecules.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nanoscience & Nanotechnology
Li Zhang, Hongcen Zheng, Yonghai Gan, Bingdang Wu, Zhihao Chen, Shuangshuang Wei, Guoyang Zhang, Shujuan Zhang, Bingcai Pan, Chuncheng Chen
Summary: This article introduces a novel method for the synthesis and functionalization of gold nanoparticles using acetylacetone. The size of the nanoparticles can be controlled by adjusting light intensity and acetylacetone dosage. The capping role of acetylacetone allows for stable dispersion in water without changes in morphology and photochemical properties. Additionally, the nanoparticles can be used as imaging probes through reactions with other substances.
Article
Chemistry, Multidisciplinary
Jianing Guo, Bingjie Li, Qiyu Zhang, Qingtao Liu, Zelin Wang, Yufei Zhao, Jianglan Shui, Zhonghua Xiang
Summary: The study introduces a facile method for synthesizing atomically dispersed Fe-N-x species on hierarchically porous carbon nanostructures as an efficient and stable catalyst for oxygen reduction in acidic media for proton exchange membrane fuel cells. The designed hierarchical pore structure facilitates mass transport and utilization of active sites, leading to higher power density in devices.
Article
Chemistry, Physical
Munusamy Kesava, Kannaiyan Dinakaran
Summary: A new poly (arylene ether sulfone) (CPAEs) polymer carboxylated through a Thiol Ene reaction was synthesized and characterized, along with SnO2 nanoparticles, using various analytical techniques. The properties of CPAEs/SnO2 nanocomposite membranes with different SnO2 loading levels were evaluated, showing that the 3% SnO2 NPs loaded membrane exhibited excellent ion exchange capacity and proton conductivity.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2021)
Article
Chemistry, Physical
Xingru Yan, Shuo Huang, Fan Yang, Siyuan Sun, Ge Zhang, Bo Jiang, Bing Zhang, Sai Che, Wang Yang, Yongfeng Li
Summary: A high-performance and non-noble metal hydrogen evolution reaction (HER) electrocatalyst (Ni2P/PC) was developed using a facile hydrothermal synthesis, demonstrating excellent electrocatalytic activity. The PC substrate successfully adjusted the electron density of Ni2P, leading to improved catalyst performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Review
Engineering, Environmental
Fanchi Meng, Pengbo Zhu, Lini Yang, Lixin Xia, Hongyang Liu
Summary: Nanozymes, with their great enzyme-like catalytic performance and biological characteristics, have become a research hotspot in the biomedical field. The discovery of nanozymes with atomically dispersed metal centers has brought research to the atomic level, leading to higher atomic utilization rate and stronger catalytic performance. Atomically dispersed active centers are beneficial for the regulation of catalytic performance and the study of structure-activity relationships. Currently, nanozymes with atomically dispersed metal centers have shown significant application value in the biomedical field.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Jiali Chai, Ke Wang, Qingmeng Li, Jiakai Du, Lei Jiang, Ning Han, Wei Zhang, Bohejin Tang, Yichuan Rui
Summary: In this study, a novel lithium-ion battery anode material, ZIF-4@CuO, is proposed. Highly dispersed CuO nanoparticles were prepared by hydrogen extraction reaction and precursor decomposition, which were combined with the ZIF-4 framework to strongly promote the reaction kinetics of the electrode. ZIF-4@CuO exhibited excellent electrochemical performance in LIBs.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Jing Jin, Junjie Mao, Wenjie Wu, Ying Jiang, Wenjie Ma, Ping Yu, Lanqun Mao
Summary: This study reports a biomimetic catalyst based on single-iron atoms for efficient and controlled NO generation, showing great potential for biomedical applications.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
George S. Biggs, Oskar James Klein, Sarah L. Maslen, J. Mark Skehel, Trevor J. Rutherford, Stefan M. V. Freund, Florian Hollfelder, Sally R. Boss, Paul D. Barker
Summary: The study focuses on generating artificial metalloenzymes through ligand exchange, with a fast and robust procedure developed using Ru-II(eta(6)-arene)(bipyridine) complexes. By successfully introducing metal cofactors into proteins to generate catalysts, the research demonstrates a significant increase in catalytic activity.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Yuan Dong, Jie Ying, Yu-Xuan Xiao, Jiang-Bo Chen, Xiao-Yu Yang
Summary: A novel strategy was presented to synthesize highly dispersed Pt nanoparticles embedded in N-doped porous carbon, exhibiting superior activity and durability in the hydrogen evolution reaction compared to commercial Pt/C catalyst. The excellent performance can be attributed to the combined features of catalyst and support material, including Pt dispersion, surface area and nitrogen doping of carbon, and strong metal-support interaction.
CHEMISTRY-AN ASIAN JOURNAL
(2021)
Article
Oncology
Shuntaro Mukai, Shota Moriya, Masaki Hiramoto, Hiromi Kazama, Hiroko Kokuba, Xiao-Fang Che, Tomohisa Yokoyama, Satoshi Sakamoto, Akihiro Sugawara, Toshiaki Sunazuka, Satoshi Omura, Hiroshi Handa, Takao Itoi, Keisuke Miyazawa
INTERNATIONAL JOURNAL OF ONCOLOGY
(2016)
Article
Chemistry, Medicinal
Marco Boccitto, Nayoung Lee, Satoshi Sakamoto, Lynn A. Spruce, Hiroshi Handa, Jon Clardy, Steven H. Seeholzer, Robert G. Kalb
Article
Medical Laboratory Technology
Yasuaki Kabe, Makoto Suematsu, Satoshi Sakamoto, Miwa Hirai, Ikko Koike, Takako Hishiki, Atsushi Matsuda, Yuichi Hasegawa, Koji Tsujita, Masayuki Ono, Naoko Minegishi, Atsushi Hozawa, Yoshinori Murakami, Michiaki Kubo, Makoto Itonaga, Hiroshi Handa
CLINICAL CHEMISTRY
(2018)
Article
Multidisciplinary Sciences
Tomoyuki Mori, Takumi Ito, Shujie Liu, Hideki Ando, Satoshi Sakamoto, Yuki Yamaguchi, Etsuko Tokunaga, Norio Shibata, Hiroshi Handa, Toshio Hakoshima
SCIENTIFIC REPORTS
(2018)
Article
Nanoscience & Nanotechnology
Miki Kaneko, Shinichi Chikaki, Sachiko Matsuda, Akihiro Kuwahata, Masayuki Namita, Itsuro Saito, Satoshi Sakamoto, Moriaki Kusakabe, Masaki Sekino
Article
Chemistry, Multidisciplinary
Alba Perez-Perarnau, Sara Preciado, Claudia Mariela Palmeri, Cristina Moncunill-Massaguer, Daniel Iglesias-Serret, Diana M. Gonzalez-Girones, Miriam Miguel, Satoki Karasawa, Satoshi Sakamoto, Ana M. Cosialls, Camila Rubio-Patino, Jose Saura-Esteller, Rosario Ramon, Laia Caja, Isabel Fabregat, Gabriel Pons, Hiroshi Handa, Fernando Albericio, Joan Gil, Rodolfo Lavilla
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2014)
Review
Biochemical Research Methods
Yasuaki Kabe, Satoshi Sakamoto, Mamoru Hatakeyama, Yuki Yamaguchi, Makoto Suematsu, Makoto Itonaga, Hiroshi Handa
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2019)
Article
Cell Biology
Tatsuya Onishi, Sachiko Matsuda, Yuki Nakamura, Junko Kuramoto, Akinori Tsuruma, Satoshi Sakamoto, Shunichi Suzuki, Daiichiro Fuchimoto, Akira Onishi, Shinichi Chikaki, Miki Kaneko, Akihiro Kuwahata, Masaki Sekino, Hiroshi Yasuno, Naohiro Hanyu, Tomoko Kurita, Hiroyuki Takei, Takashi Sakatani, Kanae Taruno, Seigo Nakamura, Tetsu Hayashida, Hiromitsu Jinno, Moriaki Kusakabe, Hiroshi Handa, Kaori Kameyama, Yuko Kitagawa
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
(2019)
Correction
Nanoscience & Nanotechnology
Miki Kaneko, Shinichi Chikaki, Sachiko Matsuda, Akihiro Kuwahata, Masayuki Namita, Itsuro Saito, Satoshi Sakamoto, Hiroshi Handa, Moriaki Kusakabe, Masaki Sekino
Article
Multidisciplinary Sciences
Shumpei Tateno, Midori Iida, Satoshi Fujii, Tetsufumi Suwa, Miki Katayama, Haruka Tokuyama, Junichi Yamamoto, Takumi Ito, Satoshi Sakamoto, Hiroshi Handa, Yuki Yamaguchi
SCIENTIFIC REPORTS
(2020)
Article
Nanoscience & Nanotechnology
Masaki Sekino, Akihiro Kuwahata, Shunsuke Fujita, Sachiko Matsuda, Miki Kaneko, Shinichi Chikaki, Satoshi Sakamoto, Itsuro Saito, Hiroshi Handa, Moriaki Kusakabe
Article
Nanoscience & Nanotechnology
Masaki Sekino, Akihiro Kuwahata, Akinobu Yoshibe, Kiyotaka Imai, Miki Kaneko, Shinichi Chikaki, Itsuro Saito, Akinori Tsuruma, Satoshi Sakamoto, Hiroshi Handa, Sachiko Matsuda, Moriaki Kusakabe
Article
Biochemistry & Molecular Biology
Jaeyong Cho, Masaki Hiramoto, Yuka Masaike, Satoshi Sakamoto, Yoichi Imai, Yumi Imai, Hiroshi Handa, Takeshi Imai
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2020)
Review
Oncology
Tatsuya Onishi, Kisyo Mihara, Sachiko Matsuda, Satoshi Sakamoto, Akihiro Kuwahata, Masaki Sekino, Moriaki Kusakabe, Hiroshi Handa, Yuko Kitagawa
Summary: Screening, monitoring, and diagnostic methods in oncology are critical for treatment. Current clinical methods have limitations in terms of time, cost, and special facilities required for radioisotope-based techniques. Magnetic nanoparticles provide an alternative approach that offers faster analyses with safer materials for various oncological applications.
Article
Multidisciplinary Sciences
Hideki Ando, Tomomi Sato, Takumi Ito, Junichi Yamamoto, Satoshi Sakamoto, Nobuhiro Nitta, Tomoko Asatsuma-Okumura, Nobuyuki Shimizu, Ryota Mizushima, Ichio Aoki, Takeshi Imai, Yuki Yamaguchi, Arnold J. Berk, Hiroshi Handa